PMID- 34307584 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210727 IS - 2307-8960 (Print) IS - 2307-8960 (Electronic) IS - 2307-8960 (Linking) VI - 9 IP - 19 DP - 2021 Jul 6 TI - Four-year-old anti-N-methyl-D-aspartate receptor encephalitis patient with ovarian teratoma: A case report. PG - 5319-5324 LID - 10.12998/wjcc.v9.i19.5319 [doi] AB - BACKGROUND: A population-based comparative study in United States shows that the prevalence and incidence of autoimmune encephalitis are comparable to those of infectious encephalitis and its detection is increasing over time. Some patients are complicated with ovarian teratoma. The younger the patient is, the less likely a tumor will be present. CASE SUMMARY: This case report describes the successful treatment of anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis by early laparoscopic ovarian cystectomy and immunotherapy in a 4-year-old female child. And to the best of our knowledge, this detailed case report describes the youngest patient to date with anti-NMDAR encephalitis who underwent laparoscopic ovarian cystectomy. CONCLUSION: Although the younger the patient is, the less likely a tumor will be detected, we still emphasize that all patients with suspected or confirmed anti-NMDAR encephalitis should be screened for ovarian tumors if possible. Prompt initiation of immunotherapy and tumor removal are crucial for good outcomes. CI - (c)The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. FAU - Xue, Cong-Ying AU - Xue CY AD - Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China. FAU - Dong, Hui AU - Dong H AD - Department of Pediatrics, Peking University First Hospital, Beijing 100034, China. FAU - Yang, Hui-Xia AU - Yang HX AD - Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China. FAU - Jiang, Yu-Wu AU - Jiang YW AD - Department of Pediatrics, Peking University First Hospital, Beijing 100034, China. FAU - Yin, Ling AU - Yin L AD - Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China. yinling6565@sina.com. LA - eng PT - Case Reports PL - United States TA - World J Clin Cases JT - World journal of clinical cases JID - 101618806 PMC - PMC8283584 OTO - NOTNLM OT - Anti-N-methyl-D-aspartate receptor encephalitis OT - Case report OT - Childhood OT - Laparoscopic surgery OT - Ovarian teratoma COIS- Conflict-of-interest statement: The authors claim no conflict of interest related to this manuscript. EDAT- 2021/07/27 06:00 MHDA- 2021/07/27 06:01 PMCR- 2021/07/06 CRDT- 2021/07/26 06:39 PHST- 2021/02/27 00:00 [received] PHST- 2021/04/25 00:00 [revised] PHST- 2021/05/07 00:00 [accepted] PHST- 2021/07/26 06:39 [entrez] PHST- 2021/07/27 06:00 [pubmed] PHST- 2021/07/27 06:01 [medline] PHST- 2021/07/06 00:00 [pmc-release] AID - 10.12998/wjcc.v9.i19.5319 [doi] PST - ppublish SO - World J Clin Cases. 2021 Jul 6;9(19):5319-5324. doi: 10.12998/wjcc.v9.i19.5319.