PMID- 34313373
OWN - NLM
STAT- MEDLINE
DCOM- 20211115
LR  - 20211115
IS  - 1097-0029 (Electronic)
IS  - 1059-910X (Linking)
VI  - 84
IP  - 12
DP  - 2021 Dec
TI  - La(3+) and F(-) dual-doped multifunctional hydroxyapatite nanoparticles: 
      Synthesis and characterization.
PG  - 3211-3220
LID - 10.1002/jemt.23880 [doi]
AB  - Hydroxyapatite (HA) co-doped with La(3+) and F(-) ions were synthesized by the 
      precipitation method and sintered at 1,100 degrees C for 1 hr. Samples were characterized 
      by the standard experimental methods including the density, X-Ray Diffraction 
      (XRD), Fourier Transform Infrared Spectroscopy (FTIR), and Scanning Electron 
      Microscopy (SEM) to investigate their microstructure, phase formation, and 
      bonding characteristics in detail. Moreover, the materials produced were 
      identified using the microhardness tests. It was observed that in the most of 
      materials, the hydroxyapatite was found to be the main phase with a minor amount 
      of beta-tricalcium phosphate (beta-TCP). Furthermore, the presence of fluoride and 
      small amount of beta-TCP was verified with all the characteristic FTIR bands of 
      hydroxyapatite for the majority of samples studied. The result in SEM evaluation 
      is that the produced HA powders have less deformed, uniformly distributed, and 
      regularly shaped particles. Here, the material density has changed towards a less 
      dense state with the increasing rate of La doping, but statistically significant 
      difference was not obtained (p, .1942 > .05) with increase of the F doping. A 
      significant difference was obtained the microhardness values between La(3+) and 
      F(-) ions co-doped HA materials and pure HA (p [.0053] < .05). Accordingly, this 
      study confirmed that since the La(3+) and F(-) ions can potentially increase the 
      efficacy of HA. According to the spectral, mechanical, and microstructure 
      analysis result, this material can be as a good candidate product for use as an 
      occluding material for dental application.
CI  - (c) 2021 Wiley Periodicals LLC.
FAU - Erdem, Umit
AU  - Erdem U
AUID- ORCID: 0000-0002-0480-8176
AD  - Scientific and Technical Research Center, Kirikkale University, Kirikkale, 
      Turkey.
FAU - Turkoz, Mustafa B
AU  - Turkoz MB
AD  - Faculty of Engineering, Electric and Electronics Engineering, Karabuk University, 
      Karabuk, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20210727
PL  - United States
TA  - Microsc Res Tech
JT  - Microscopy research and technique
JID - 9203012
RN  - 91D9GV0Z28 (Durapatite)
RN  - Q80VPU408O (Fluorides)
SB  - IM
MH  - *Durapatite
MH  - Fluorides
MH  - *Nanoparticles
MH  - Spectroscopy, Fourier Transform Infrared
MH  - X-Ray Diffraction
OTO - NOTNLM
OT  - dual doping
OT  - fluoride
OT  - hydroxyapatite
OT  - lanthanum
OT  - microstructure
EDAT- 2021/07/28 06:00
MHDA- 2021/11/16 06:00
CRDT- 2021/07/27 08:52
PHST- 2021/07/06 00:00 [revised]
PHST- 2021/04/05 00:00 [received]
PHST- 2021/07/11 00:00 [accepted]
PHST- 2021/07/28 06:00 [pubmed]
PHST- 2021/11/16 06:00 [medline]
PHST- 2021/07/27 08:52 [entrez]
AID - 10.1002/jemt.23880 [doi]
PST - ppublish
SO  - Microsc Res Tech. 2021 Dec;84(12):3211-3220. doi: 10.1002/jemt.23880. Epub 2021 
      Jul 27.