PMID- 34315609 OWN - NLM STAT- MEDLINE DCOM- 20220317 LR - 20220317 IS - 1879-1476 (Electronic) IS - 0385-8146 (Linking) VI - 49 IP - 2 DP - 2022 Apr TI - Establishment of a non-squamous cell carcinoma of the larynx nomogram prognostic model and prognosis analysis. PG - 240-247 LID - S0385-8146(21)00199-1 [pii] LID - 10.1016/j.anl.2021.07.008 [doi] AB - OBJECTIVE: We aimed to compare the prognosis of laryngeal squamous cell carcinoma (LSCC) and nSCCs of the larynx.Then we established a nomogram for nSCCs of the larynx. METHODS: Prognosis between the 529 pairs nSCCs of the larynx patients and LSCC patients were compared after propensity score matching (PSM). 591 nSCCs of the larynx patients were divided into the modeling and validation groups. Univariate and multivariate Cox analyses obtain independent prognostic factors, which were then included in the nomogram to predict the 3 and 5 year survival. Prognostic accuracy of the nomogram was evaluated using the consistency index (C-index) and the calibration curve. RESULTS: Prognosis of nSCCs of the larynx was poorer than LSCC. Age, race, tumor location, tumor-node-metastasis stage, and method were independent prognostic factors of nSCCs of the larynx (P < 0.05). Internal and external validation proves the nomogram reliable CONCLUSION: The nomogram showed good prognostic accuracy and would assist clinicians in making more accurate evaluations for patients. CI - Copyright (c) 2021. Published by Elsevier B.V. FAU - Fan, Lin AU - Fan L AD - Department of Otolaryngology-Head and Neck Surgery,The Second Affiliated Hospital of Harbin Medical University, Haerbin,China. FAU - Zhao, Rui AU - Zhao R AD - Department of Otolaryngology-Head and Neck Surgery,The Second Affiliated Hospital of Harbin Medical University, Haerbin,China. FAU - Chen, Xiumei AU - Chen X AD - Department of Otolaryngology-Head and Neck Surgery,Yantai Yuhuangding Hospital,Yantai,China. FAU - Liu, Yaohui AU - Liu Y AD - Department of Otolaryngology-Head and Neck Surgery,The Second Affiliated Hospital of Harbin Medical University, Haerbin,China. FAU - Tian, Linli AU - Tian L AD - Department of Otolaryngology-Head and Neck Surgery,The Second Affiliated Hospital of Harbin Medical University, Haerbin,China. Electronic address: tianlinli78@163.com. FAU - Liu, Ming AU - Liu M AD - Department of Otolaryngology-Head and Neck Surgery,The Second Affiliated Hospital of Harbin Medical University, Haerbin,China. Electronic address: liumingorl@qq.com. LA - eng PT - Journal Article DEP - 20210725 PL - Netherlands TA - Auris Nasus Larynx JT - Auris, nasus, larynx JID - 7708170 SB - IM MH - *Head and Neck Neoplasms MH - Humans MH - *Laryngeal Neoplasms/pathology MH - *Larynx MH - Nomograms MH - Prognosis OTO - NOTNLM OT - Laryngeal cancer OT - Nomogram OT - PSM analysis OT - Prognosis COIS- Declaration of Competing Interest The authors declare that they have no conflicts of interest EDAT- 2021/07/29 06:00 MHDA- 2022/03/18 06:00 CRDT- 2021/07/28 05:41 PHST- 2021/05/25 00:00 [received] PHST- 2021/06/27 00:00 [revised] PHST- 2021/07/07 00:00 [accepted] PHST- 2021/07/29 06:00 [pubmed] PHST- 2022/03/18 06:00 [medline] PHST- 2021/07/28 05:41 [entrez] AID - S0385-8146(21)00199-1 [pii] AID - 10.1016/j.anl.2021.07.008 [doi] PST - ppublish SO - Auris Nasus Larynx. 2022 Apr;49(2):240-247. doi: 10.1016/j.anl.2021.07.008. Epub 2021 Jul 25.