PMID- 34327096 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240402 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 13 IP - 6 DP - 2021 Jun TI - A Case of Spontaneous Pneumomediastinum Following Ecstasy and Marijuana Use. PG - e15871 LID - 10.7759/cureus.15871 [doi] LID - e15871 AB - Spontaneous pneumomediastinum (SPM) is a benign and self-limiting condition more commonly seen in young adults. Radiology imaging of the chest, including X-ray or CT scan, is the gold standard for diagnosis. Ecstasy, also known as 3,4-methylenedioxymethamphetamine (MDMA) is a synthetic amphetamine derivative widely abused for an increased sense of well-being and euphoria. Marijuana is also abused for recreational purposes. SPM has been reported after both Ecstasy and marijuana use. SPM after these illicit drugs abuse usually has a benign and self-limiting course with supportive management. However, it is always important to rule out serious associated conditions like esophageal perforation. Here, we present a 22-year-old male who developed SPM after Ecstasy ingestion and marijuana inhalation. CI - Copyright (c) 2021, Paul et al. FAU - Paul, Mishouri AU - Paul M AD - Medicine, Interfaith Medical Center, New York City, USA. FAU - Paul, Prodip AU - Paul P AD - Internal Medicine, Geisinger Community Medical Center, Scranton, USA. FAU - Dey, Dipon AU - Dey D AD - Epidemiology and Public Health, ZWH Medical Care PC, Queens, USA. FAU - Bhardwaj, Amit AU - Bhardwaj A AD - Internal Medicine, Geisinger Community Medical Center, Scranton, USA. FAU - Paul, Koushik AU - Paul K AD - Clinical Pathology, Community Based Medical College Hospital, Mymensingh, BGD. LA - eng PT - Case Reports DEP - 20210623 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC8302393 OTO - NOTNLM OT - boerhaave's syndrome OT - ecstasy OT - marijuana OT - pneumomediastinum OT - subcutaneous emphysema COIS- The authors have declared that no competing interests exist. EDAT- 2021/07/31 06:00 MHDA- 2021/07/31 06:01 PMCR- 2021/06/23 CRDT- 2021/07/30 06:47 PHST- 2021/06/20 00:00 [accepted] PHST- 2021/07/30 06:47 [entrez] PHST- 2021/07/31 06:00 [pubmed] PHST- 2021/07/31 06:01 [medline] PHST- 2021/06/23 00:00 [pmc-release] AID - 10.7759/cureus.15871 [doi] PST - epublish SO - Cureus. 2021 Jun 23;13(6):e15871. doi: 10.7759/cureus.15871. eCollection 2021 Jun.