PMID- 34327510
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210731
IS  - 2688-4844 (Electronic)
IS  - 2688-4844 (Linking)
VI  - 2
IP  - 1
DP  - 2021
TI  - Nonablative, Noncoagulative Multipolar Radiofrequency and Pulsed Electromagnetic 
      Field Treatment Improves Vaginal Laxity and Sexual Function.
PG  - 285-294
LID - 10.1089/whr.2021.0020 [doi]
AB  - Objective: This study investigated nonablative/noncoagulative multipolar 
      radiofrequency and pulsed electromagnetic field (RF/PEMF) treatment for vaginal 
      laxity (VL) and its impact on sexual function in parous women. Methods: This 
      prospective, open-label single-center study enrolled 34 female subjects, 23-59 
      years of age, with >/=1 vaginal delivery and self-reported VL. Three monthly 
      intravaginal treatments with RF/PEMF energy were performed. Treatment and 
      follow-up assessments included the vaginal health index (VHI), vaginal pH, female 
      sexual function index (FSFI), and VL/sexual satisfaction (SS) and subject 
      satisfaction scores. Mean score and percent improvement over baseline were 
      reported. Subject discomfort/pain was assessed after each treatment. Results: 
      Total and each individual domain scores of the VHI improved significantly, while 
      vaginal pH levels decreased from baseline to both 1 and 4 months (p < 0.01) after 
      the last treatment. FSFI (<0.001), VL (<0.001), and SS (<0.001), including 
      overall satisfaction scores (<0.01), improved post-treatment, with positive 
      effects further sustained until at least 4 months post-treatment. Pain/discomfort 
      post-treatment was reported as none to mild. No noticeable adverse events (AEs) 
      or unanticipated side effects were reported. Conclusions: 
      Nonablative/noncoagulative multipolar RF/PEMF is safe and is associated with 
      significant 1- and 4-month post-treatment improvements in symptoms associated 
      with VL and sexual dysfunction, as assessed by the VHI, vaginal pH, FSFI, and VL 
      subject satisfaction score. SS and overall satisfaction scores also improved. The 
      treatment was well tolerated with no or little pain, and no adverse events were 
      reported. Clinical Trial Registration number: NCT04607798.
CI  - (c) Yegor Kolodchenko 2021; Published by Mary Ann Liebert, Inc.
FAU - Kolodchenko, Yegor
AU  - Kolodchenko Y
AD  - Association of Laser Medicine and Cosmetology, Cogerent Laser Clinic, Kyiv, 
      Ukraine.
LA  - eng
SI  - ClinicalTrials.gov/NCT04607798
PT  - Journal Article
DEP - 20210727
PL  - United States
TA  - Womens Health Rep (New Rochelle)
JT  - Women's health reports (New Rochelle, N.Y.)
JID - 101768931
PMC - PMC8317596
OTO - NOTNLM
OT  - female sexual dysfunction
OT  - multi-polar radio frequency
OT  - pulsed electromagnetic field
OT  - vaginal laxity
COIS- Y.K. received funding for the study.
EDAT- 2021/07/31 06:00
MHDA- 2021/07/31 06:01
PMCR- 2021/07/27
CRDT- 2021/07/30 06:52
PHST- 2021/06/18 00:00 [accepted]
PHST- 2021/07/30 06:52 [entrez]
PHST- 2021/07/31 06:00 [pubmed]
PHST- 2021/07/31 06:01 [medline]
PHST- 2021/07/27 00:00 [pmc-release]
AID - 10.1089/whr.2021.0020 [pii]
AID - 10.1089/whr.2021.0020 [doi]
PST - epublish
SO  - Womens Health Rep (New Rochelle). 2021 Jul 27;2(1):285-294. doi: 
      10.1089/whr.2021.0020. eCollection 2021.