PMID- 34327598
OWN - NLM
STAT- MEDLINE
DCOM- 20220113
LR  - 20220113
IS  - 1661-4917 (Electronic)
IS  - 0004-069X (Linking)
VI  - 69
IP  - 1
DP  - 2021 Jul 29
TI  - Stimulation of Innate and Adaptive Immune Cells with Graphene Oxide and Reduced 
      Graphene Oxide Affect Cancer Progression.
PG  - 20
LID - 10.1007/s00005-021-00625-6 [doi]
AB  - Sole nanomaterials or nanomaterials bound to specific biomolecules have been 
      proposed to regulate the immune system. These materials have now emerged as new 
      tools for eliciting immune-based therapies to treat various cancers. Graphene, 
      graphene oxide (GO) and reduced GO (rGO) are the latest nanomaterials among other 
      carbon nanotubes that have attracted wide interest among medical industry players 
      due to their extraordinary properties, inert-state, non-toxic and stable 
      dispersion in a various solvent. Currently, GO and rGO are utilized in various 
      biomedical application including cancer immunotherapy. This review will highlight 
      studies that have been carried out in elucidating the stimulation of GO and rGO 
      on selected innate and adaptive immune cells and their effect on cancer 
      progression to shed some insights for researchers in the development of various 
      GO- and rGO-based immune therapies against various cancers.
CI  - (c) 2021. L. Hirszfeld Institute of Immunology and Experimental Therapy, Wroclaw, 
      Poland.
FAU - Yunus, Muhammad Amir
AU  - Yunus MA
AD  - Infectomics Cluster, Advanced Medical and Dental Institute, Universiti Sains 
      Malaysia, Bertam, 13200, Kepala Batas, Pulau Pinang, Malaysia.
FAU - Ramli, Muhammad Mahyiddin
AU  - Ramli MM
AD  - Geopolymer and Green Technology, Centre of Excellence (CEGeoGTech), Universiti 
      Malaysia Perlis (UniMAP), Perlis, Malaysia.
AD  - Faculty of Electronic Engineering Technology, Universiti Malaysia Perlis 
      (UniMAP), Perlis, Malaysia.
FAU - Osman, Nurul Huda
AU  - Osman NH
AD  - Faculty of Science, Department of Physics, Applied Electromagnetic Laboratory 1, 
      Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
FAU - Mohamed, Rafeezul
AU  - Mohamed R
AD  - Regenerative Medicine Cluster, Advanced Medical and Dental Institute, Universit 
      Sains Malaysia, Bertam, 13200, Kepala Batas, Pulau Pinang, Malaysia. 
      rafeezul@usm.my.
LA  - eng
GR  - (1001/CIPPT/8012205)/Universiti Sains Malaysia/
PT  - Journal Article
PT  - Review
DEP - 20210729
PL  - Poland
TA  - Arch Immunol Ther Exp (Warsz)
JT  - Archivum immunologiae et therapiae experimentalis
JID - 0114365
RN  - 0 (Nanotubes, Carbon)
RN  - 0 (Oxides)
RN  - 0 (graphene oxide)
RN  - 7782-42-5 (Graphite)
SB  - IM
MH  - *Graphite
MH  - Humans
MH  - *Nanotubes, Carbon
MH  - *Neoplasms/therapy
MH  - Oxides
OTO - NOTNLM
OT  - Adaptive immune cells
OT  - Cancers
OT  - Graphene oxide
OT  - Innate immune cells
OT  - Reduced graphene oxide
EDAT- 2021/07/31 06:00
MHDA- 2022/01/14 06:00
CRDT- 2021/07/30 06:55
PHST- 2020/11/09 00:00 [received]
PHST- 2021/06/16 00:00 [accepted]
PHST- 2021/07/30 06:55 [entrez]
PHST- 2021/07/31 06:00 [pubmed]
PHST- 2022/01/14 06:00 [medline]
AID - 10.1007/s00005-021-00625-6 [pii]
AID - 10.1007/s00005-021-00625-6 [doi]
PST - epublish
SO  - Arch Immunol Ther Exp (Warsz). 2021 Jul 29;69(1):20. doi: 
      10.1007/s00005-021-00625-6.