PMID- 34327634
OWN - NLM
STAT- MEDLINE
DCOM- 20220316
LR  - 20220318
IS  - 1573-2649 (Electronic)
IS  - 0962-9343 (Print)
IS  - 0962-9343 (Linking)
VI  - 31
IP  - 3
DP  - 2022 Mar
TI  - Assessing measurement invariance in the EORTC QLQ-C30.
PG  - 889-901
LID - 10.1007/s11136-021-02961-8 [doi]
AB  - PURPOSE: We aimed to investigate measurement invariance (MI) in the European 
      Organisation for research and treatment of cancer quality of life questionnaire 
      core 30 (EORTC QLQ-C30) in a heterogeneous sample of patients with cancer. 
      METHODS: Data from 12 studies within the PROFILES registry were used for 
      secondary analyses (n = 7007). We tested MI by successive restrictions on 
      thresholds, loadings, and intercepts across subgroups based on primary cancer 
      sites, age, sex, time since diagnosis, and life stage, using multigroup 
      confirmatory factor analysis (MGCFA) for ordered categorical measures. We also 
      evaluated the impact of potentially miss-specified parameter equality across 
      groups on latent factor means by releasing threshold and loading equality 
      constraints for each item at a time. RESULTS: Results showed that the highest 
      level of MI (invariance of thresholds, loadings, and intercepts) was found across 
      groups based on time since diagnosis and life stage and to a lesser extent across 
      groups based on sex, age, and primary tumor site. On item level, however, changes 
      in the item's associated factor means were relatively small and in most cases 
      canceled each other out to some extent. CONCLUSIONS: Given only a few instances 
      of non-invariance in our study, there is reason to be confident that valid 
      conclusions can be drawn from between-group comparisons of QLQ-C30 latent means 
      as operationalized in our study. Nonetheless, further research into MI between 
      other subgroups for the QLQ-C30 (i.e., treatment effects and ethnicity) is 
      warranted. We stress the importance of including MI evaluations in the 
      development and validation of measurement instruments.
CI  - (c) 2021. The Author(s).
FAU - van Roij, Janneke
AU  - van Roij J
AUID- ORCID: 0000-0003-0787-3018
AD  - The Netherlands Comprehensive Cancer Organisation, PO box 19079, Utrecht, 3501, 
      DB, The Netherlands. j.vanroij@iknl.nl.
AD  - Department of Medical and Clinical Psychology, Center of Research on Psychology 
      in Somatic Diseases (CoRPS), Tilburg University, Tilburg, the Netherlands. 
      j.vanroij@iknl.nl.
AD  - Netherlands Association for Palliative Care (PZNL), Utrecht, The Netherlands. 
      j.vanroij@iknl.nl.
FAU - Kieffer, Jacobien M
AU  - Kieffer JM
AD  - Division of Psychosocial Research and Epidemiology, The Netherlands Cancer 
      Institute, Amsterdam, The Netherlands.
FAU - van de Poll-Franse, Lonneke
AU  - van de Poll-Franse L
AD  - The Netherlands Comprehensive Cancer Organisation, PO box 19079, Utrecht, 3501, 
      DB, The Netherlands.
AD  - Department of Medical and Clinical Psychology, Center of Research on Psychology 
      in Somatic Diseases (CoRPS), Tilburg University, Tilburg, the Netherlands.
AD  - Division of Psychosocial Research and Epidemiology, The Netherlands Cancer 
      Institute, Amsterdam, The Netherlands.
FAU - Husson, Olga
AU  - Husson O
AD  - Division of Psychosocial Research and Epidemiology, The Netherlands Cancer 
      Institute, Amsterdam, The Netherlands.
AD  - The Institute of Cancer Research and the Royal Marsden NHS Foundation Trust, 
      London, UK.
FAU - Raijmakers, Natasja J H
AU  - Raijmakers NJH
AD  - The Netherlands Comprehensive Cancer Organisation, PO box 19079, Utrecht, 3501, 
      DB, The Netherlands.
AD  - Netherlands Association for Palliative Care (PZNL), Utrecht, The Netherlands.
FAU - Gelissen, John
AU  - Gelissen J
AD  - Department of Methodology and Statistics, Tilburg School of Social and Behavioral 
      Sciences, Tilburg University, Tilburg, The Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20210729
PL  - Netherlands
TA  - Qual Life Res
JT  - Quality of life research : an international journal of quality of life aspects of 
      treatment, care and rehabilitation
JID - 9210257
SB  - IM
MH  - Factor Analysis, Statistical
MH  - Humans
MH  - *Neoplasms/therapy
MH  - *Quality of Life/psychology
MH  - Surveys and Questionnaires
PMC - PMC8921013
OTO - NOTNLM
OT  - Measurement invariance
OT  - Medical oncology
OT  - Palliative care
OT  - Patient-reported outcomes
OT  - Quality of life
OT  - Validation studies
COIS- The authors declare that they have no conflict of interest.
EDAT- 2021/07/31 06:00
MHDA- 2022/03/17 06:00
PMCR- 2021/07/29
CRDT- 2021/07/30 06:57
PHST- 2021/07/24 00:00 [accepted]
PHST- 2021/07/31 06:00 [pubmed]
PHST- 2022/03/17 06:00 [medline]
PHST- 2021/07/30 06:57 [entrez]
PHST- 2021/07/29 00:00 [pmc-release]
AID - 10.1007/s11136-021-02961-8 [pii]
AID - 2961 [pii]
AID - 10.1007/s11136-021-02961-8 [doi]
PST - ppublish
SO  - Qual Life Res. 2022 Mar;31(3):889-901. doi: 10.1007/s11136-021-02961-8. Epub 2021 
      Jul 29.