PMID- 34331249
OWN - NLM
STAT- MEDLINE
DCOM- 20210816
LR  - 20210816
IS  - 1940-6029 (Electronic)
IS  - 1064-3745 (Linking)
VI  - 2319
DP  - 2021
TI  - Visualization of Retinal Blood Vessels.
PG  - 111-117
LID - 10.1007/978-1-0716-1480-8_13 [doi]
AB  - The retina offers a unique opportunity to directly visualize blood vessels in 
      vivo noninvasively. Over the past few decades, several new imaging techniques 
      have been adapted to study the retinal vasculature in the laboratory in animal 
      models and in the clinic in human subjects. High-contrast, finely detailed fundus 
      images can be acquired by confocal scanning laser ophthalmoscopy (cSLO). With 
      fluorescein angiography (FA), the retinal microcirculation can be visualized. 
      High-resolution spectral-domain optical coherence tomography (SD-OCT) is able to 
      acquire cross-section images resolving the microarchitecture of the retina, 
      similar to histology. The techniques and protocols for acquiring cSLO, FA, and 
      SD-OCT imaging of the retinal vasculature and morphology in the rodent are 
      described.
CI  - (c) 2021. Springer Science+Business Media, LLC, part of Springer Nature.
FAU - Xie, Wankun
AU  - Xie W
AD  - Department of Medical Physiology, College of Medicine, Texas A&M University Heath 
      Science Center, Bryan, TX, USA.
AD  - Department of Ophthalmology, Baylor Scott & White Eye Institute, Temple, TX, USA.
FAU - Zhao, Min
AU  - Zhao M
AD  - Department of Medical Physiology, College of Medicine, Texas A&M University Heath 
      Science Center, Bryan, TX, USA.
AD  - Department of Ophthalmology, Baylor Scott & White Eye Institute, Temple, TX, USA.
FAU - Hein, Travis W
AU  - Hein TW
AD  - Department of Medical Physiology, College of Medicine, Texas A&M University Heath 
      Science Center, Bryan, TX, USA.
AD  - Department of Ophthalmology, Baylor Scott & White Eye Institute, Temple, TX, USA.
FAU - Kuo, Lih
AU  - Kuo L
AD  - Department of Medical Physiology, College of Medicine, Texas A&M University Heath 
      Science Center, Bryan, TX, USA.
AD  - Department of Ophthalmology, Baylor Scott & White Eye Institute, Temple, TX, USA.
FAU - Rosa, Robert H Jr
AU  - Rosa RH Jr
AD  - Department of Medical Physiology, College of Medicine, Texas A&M University Heath 
      Science Center, Bryan, TX, USA. RRosa@TAMU.edu.
AD  - Department of Ophthalmology, Baylor Scott & White Eye Institute, Temple, TX, USA. 
      RRosa@TAMU.edu.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Methods Mol Biol
JT  - Methods in molecular biology (Clifton, N.J.)
JID - 9214969
SB  - IM
MH  - Animals
MH  - Fluorescein Angiography/instrumentation/*methods
MH  - Ophthalmoscopy/*methods
MH  - Retina/*diagnostic imaging/metabolism
MH  - Retinal Vessels/*diagnostic imaging/metabolism
MH  - Tomography, Optical Coherence/instrumentation/*methods
OTO - NOTNLM
OT  - Animal
OT  - Confocal scanning laser ophthalmoscopy (cSLO)
OT  - Fluorescein angiography (FA)
OT  - Protocol
OT  - Spectral-domain optical coherence tomography (SD-OCT)
EDAT- 2021/08/01 06:00
MHDA- 2021/08/17 06:00
CRDT- 2021/07/31 08:37
PHST- 2021/07/31 08:37 [entrez]
PHST- 2021/08/01 06:00 [pubmed]
PHST- 2021/08/17 06:00 [medline]
AID - 10.1007/978-1-0716-1480-8_13 [doi]
PST - ppublish
SO  - Methods Mol Biol. 2021;2319:111-117. doi: 10.1007/978-1-0716-1480-8_13.