PMID- 34338616
OWN - NLM
STAT- MEDLINE
DCOM- 20221115
LR  - 20221222
IS  - 2045-7723 (Electronic)
IS  - 1079-0268 (Print)
IS  - 1079-0268 (Linking)
VI  - 45
IP  - 6
DP  - 2022 Nov
TI  - Similar fat and carbohydrate oxidation in response to arm cycling exercise in 
      persons with spinal cord injury versus able-bodied.
PG  - 840-847
LID - 10.1080/10790268.2021.1952385 [doi]
AB  - CONTEXT: Persons with spinal cord injury (SCI) present with low fat oxidation 
      that is associated with poor cardiometabolic health. This study compared changes 
      in fat and carbohydrate (CHO) oxidation during moderate intensity continuous 
      exercise in persons with SCI and able-bodied adults (AB). DESIGN: Repeated 
      measures, within-subjects study. SETTING: University laboratory in San Diego, CA. 
      PARTICIPANTS: Nine men and women with SCI (age and time since injury = 32 +/- 11 yr 
      and 7 +/- 6 yr) and 10 AB adults (age = 25 +/- 8 yr). INTERVENTIONS: To assess peak 
      oxygen uptake (VO(2)peak) and peak power output (PPO), participants performed 
      progressive arm ergometry to volitional exhaustion. Subsequently, they completed 
      25 min of continuous exercise at 45%PPO. OUTCOME MEASURES: Respiratory exchange 
      ratio (RER), fat and CHO oxidation, and blood lactate concentration (BLa) were 
      assessed. RESULTS: Data showed a similar RER (P = 0.98) during exercise in SCI 
      (0.97 +/- 0.04) versus AB (0.97 +/- 0.03) reflecting high CHO use and no differences 
      in BLa (3.5 +/- 1.1 and 3.0 +/- 0.9 vs. mM, P = 0.56) or fat and CHO oxidation 
      between groups (P > 0.05). However, participants with SCI exercised at a higher 
      relative intensity (P < 0.01, 84 +/- 7 vs. 75 +/- 7%HRpeak) versus AB. CONCLUSION: 
      Data confirm high reliance on CHO during arm ergometry in persons with SCI. To 
      better compare substrate utilization to AB adults, we recommend that exercise be 
      prescribed according to peak heart rate due to differences in cardiorespiratory 
      fitness between groups.
FAU - Astorino, Todd A
AU  - Astorino TA
AD  - Department of Kinesiology, CSU-San Marcos, San Marcos, CA, USA.
FAU - McMillan, David W
AU  - McMillan DW
AD  - Miller School of Medicine, University of Miami, Coral Gables, FL, USA.
LA  - eng
PT  - Journal Article
DEP - 20210802
PL  - England
TA  - J Spinal Cord Med
JT  - The journal of spinal cord medicine
JID - 9504452
RN  - 0 (Carbohydrates)
SB  - IM
MH  - Adult
MH  - Male
MH  - Humans
MH  - Female
MH  - Adolescent
MH  - Young Adult
MH  - *Spinal Cord Injuries
MH  - Oxygen Consumption/physiology
MH  - Arm
MH  - Exercise Test
MH  - Carbohydrates
PMC - PMC9662004
OTO - NOTNLM
OT  - Blood lactate concentration
OT  - Fuel utilization
OT  - Metabolic health
OT  - Respiratory exchange ratio
COIS- No potential conflict of interest was reported by the author(s).
EDAT- 2021/08/03 06:00
MHDA- 2022/11/16 06:00
PMCR- 2022/08/02
CRDT- 2021/08/02 12:18
PHST- 2021/08/03 06:00 [pubmed]
PHST- 2022/11/16 06:00 [medline]
PHST- 2021/08/02 12:18 [entrez]
PHST- 2022/08/02 00:00 [pmc-release]
AID - 1952385 [pii]
AID - 10.1080/10790268.2021.1952385 [doi]
PST - ppublish
SO  - J Spinal Cord Med. 2022 Nov;45(6):840-847. doi: 10.1080/10790268.2021.1952385. 
      Epub 2021 Aug 2.