PMID- 34340234
OWN - NLM
STAT- MEDLINE
DCOM- 20220512
LR  - 20220716
IS  - 2235-3186 (Electronic)
IS  - 1660-8151 (Print)
IS  - 1660-8151 (Linking)
VI  - 146
IP  - 3
DP  - 2022
TI  - Mechanisms of Caloric Restriction-Mediated Stress-Resistance in Acute Kidney 
      Injury.
PG  - 234-238
LID - 10.1159/000517733 [doi]
AB  - Caloric restriction (CR)-mediated organ protection has been shown to be extremely 
      efficient in rodent models of acute kidney injury (AKI). Limited understanding of 
      the underlying mechanisms paired with a risk of malnourishment and feasibility 
      problems has hindered the translation of this immense potential to the patient 
      setting. In this mini-review, the current mechanistic concepts of CR-mediated 
      stress-resistance as potential key targets for renal protection in AKI will be 
      highlighted.
CI  - (c) 2021 The Author(s). Published by S. Karger AG, Basel.
FAU - Koehler, Felix C
AU  - Koehler FC
AD  - Department II of Internal Medicine and Center for Molecular Medicine Cologne, 
      University of Cologne, Faculty of Medicine and University Hospital Cologne, 
      Cologne, Germany.
AD  - CECAD, University of Cologne, Faculty of Medicine and University Hospital 
      Cologne, Cologne, Germany.
FAU - Spath, Martin R
AU  - Spath MR
AD  - Department II of Internal Medicine and Center for Molecular Medicine Cologne, 
      University of Cologne, Faculty of Medicine and University Hospital Cologne, 
      Cologne, Germany.
AD  - CECAD, University of Cologne, Faculty of Medicine and University Hospital 
      Cologne, Cologne, Germany.
FAU - Hoyer-Allo, K Johanna R
AU  - Hoyer-Allo KJR
AD  - Department II of Internal Medicine and Center for Molecular Medicine Cologne, 
      University of Cologne, Faculty of Medicine and University Hospital Cologne, 
      Cologne, Germany.
AD  - CECAD, University of Cologne, Faculty of Medicine and University Hospital 
      Cologne, Cologne, Germany.
FAU - Muller, Roman-Ulrich
AU  - Muller RU
AD  - Department II of Internal Medicine and Center for Molecular Medicine Cologne, 
      University of Cologne, Faculty of Medicine and University Hospital Cologne, 
      Cologne, Germany.
AD  - CECAD, University of Cologne, Faculty of Medicine and University Hospital 
      Cologne, Cologne, Germany.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210802
PL  - Switzerland
TA  - Nephron
JT  - Nephron
JID - 0331777
SB  - IM
MH  - *Acute Kidney Injury/prevention & control
MH  - *Caloric Restriction
MH  - Female
MH  - Humans
MH  - Kidney
MH  - Male
PMC - PMC9216310
OTO - NOTNLM
OT  - Acute kidney injury
OT  - Caloric restriction
OT  - Dietary preconditioning
OT  - Mechanisms
OT  - Stress-resistance
COIS- The authors have no conflicts of interest to declare.
EDAT- 2021/08/03 06:00
MHDA- 2022/05/14 06:00
PMCR- 2021/08/02
CRDT- 2021/08/02 20:33
PHST- 2021/04/15 00:00 [received]
PHST- 2021/06/07 00:00 [accepted]
PHST- 2021/08/03 06:00 [pubmed]
PHST- 2022/05/14 06:00 [medline]
PHST- 2021/08/02 20:33 [entrez]
PHST- 2021/08/02 00:00 [pmc-release]
AID - 000517733 [pii]
AID - nef-0146-0234 [pii]
AID - 10.1159/000517733 [doi]
PST - ppublish
SO  - Nephron. 2022;146(3):234-238. doi: 10.1159/000517733. Epub 2021 Aug 2.