PMID- 34340839
OWN - NLM
STAT- MEDLINE
DCOM- 20211115
LR  - 20220301
IS  - 1471-6771 (Electronic)
IS  - 0007-0912 (Linking)
VI  - 127
IP  - 4
DP  - 2021 Oct
TI  - Effect of erector spinae plane block on the postoperative quality of recovery 
      after laparoscopic cholecystectomy: a prospective double-blind study.
PG  - 629-635
LID - S0007-0912(21)00419-0 [pii]
LID - 10.1016/j.bja.2021.06.030 [doi]
AB  - BACKGROUND: Laparoscopic cholecystectomy is a common surgical procedure that 
      frequently results in substantial postoperative pain. Erector spinae plane block 
      (ESPB) has been shown to have beneficial postoperative analgesic effects when 
      used as a part of multimodal analgesia. The aim of this study was to determine 
      whether ESPB improves postoperative recovery quality in patients undergoing 
      laparoscopic cholecystectomy. Evaluation of the effects of ESPB on postoperative 
      pain, opioid consumption, and nausea and vomiting was the secondary objective. 
      METHODS: In this prospective double-blind study, 82 patients undergoing 
      laparoscopic cholecystectomy were randomised into one of two groups: a standard 
      multimodal analgesic regimen in Group N (control) or an ESPB was performed in 
      Group E. Preoperative and postoperative recovery quality was measured using the 
      40-item quality of recovery (QoR-40) questionnaire; postoperative pain was 
      evaluated using the numerical rating scale scores. RESULTS: Postoperative mean 
      (standard deviation) QoR-40 scores were higher in Group E (181 [7.3]) than in 
      Group N (167 [11.4]); P<0.01. With repeated measures, a significant effect of 
      group and time was demonstrated for the global QoR-40 score, P<0.01, indicating 
      better quality of recovery in Group E. Pain scores were significantly lower in 
      Group E than in Group N, both during resting and motion at T1-T8 times (P<0.01 at 
      each time). The total amount of tramadol consumed in the first 24 h was lower in 
      Group E [median 0 mg, inter-quartile range (IQR) (0-140)], than in Group N 
      [median 180 mg, IQR (150-240); P<0.01]. CONCLUSIONS: ESPB improved postoperative 
      quality of recovery in patients undergoing laparoscopic cholecystectomy. 
      Moreover, ESPB reduced pain scores and cumulative opioid consumption. CLINICAL 
      TRIAL REGISTRATION: NCT04112394.
CI  - Copyright (c) 2021 British Journal of Anaesthesia. Published by Elsevier Ltd. All 
      rights reserved.
FAU - Canitez, Ahmet
AU  - Canitez A
AD  - Department of Anaesthesiology and Reanimation, Abdulkadir Yuksel City Hospital, 
      Gaziantep, Turkey.
FAU - Kozanhan, Betul
AU  - Kozanhan B
AD  - Department of Anaesthesiology and Reanimation, University of Health Sciences, 
      Konya Education and Research Hospital, Konya, Turkey. Electronic address: 
      betulkozanhan@gmail.com.
FAU - Aksoy, Nergis
AU  - Aksoy N
AD  - Department of General Surgery, University of Health Sciences, Konya Education and 
      Research Hospital, Konya, Turkey.
FAU - Yildiz, Munise
AU  - Yildiz M
AD  - Department of Anaesthesiology and Reanimation, University of Health Sciences, 
      Konya Education and Research Hospital, Konya, Turkey.
FAU - Tutar, Mahmut S
AU  - Tutar MS
AD  - Department of Anaesthesiology and Reanimation, Konya Numune State Hospital, 
      Konya, Turkey.
LA  - eng
SI  - ClinicalTrials.gov/NCT04112394
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20210731
PL  - England
TA  - Br J Anaesth
JT  - British journal of anaesthesia
JID - 0372541
RN  - 0 (Analgesics, Opioid)
RN  - 39J1LGJ30J (Tramadol)
SB  - IM
CIN - Br J Anaesth. 2022 Mar;128(3):e225-e226. PMID: 34996590
MH  - Adolescent
MH  - Adult
MH  - Analgesics, Opioid/*administration & dosage
MH  - Cholecystectomy, Laparoscopic/*methods
MH  - Double-Blind Method
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nerve Block/*methods
MH  - Pain Measurement
MH  - Pain, Postoperative/*prevention & control
MH  - Prospective Studies
MH  - Surveys and Questionnaires
MH  - Tramadol/administration & dosage
MH  - Young Adult
OTO - NOTNLM
OT  - erector spinae plane block
OT  - laparoscopic cholecystectomy
OT  - multimodal analgesia
OT  - patient-reported outcome
OT  - postoperative pain
OT  - quality of recovery
OT  - surgery
COIS- Declarations of interest The authors declare that they have no conflicts of 
      interest.
EDAT- 2021/08/04 06:00
MHDA- 2021/11/16 06:00
CRDT- 2021/08/03 05:41
PHST- 2020/10/22 00:00 [received]
PHST- 2021/05/31 00:00 [revised]
PHST- 2021/06/27 00:00 [accepted]
PHST- 2021/08/04 06:00 [pubmed]
PHST- 2021/11/16 06:00 [medline]
PHST- 2021/08/03 05:41 [entrez]
AID - S0007-0912(21)00419-0 [pii]
AID - 10.1016/j.bja.2021.06.030 [doi]
PST - ppublish
SO  - Br J Anaesth. 2021 Oct;127(4):629-635. doi: 10.1016/j.bja.2021.06.030. Epub 2021 
      Jul 31.