PMID- 3434228
OWN - NLM
STAT- MEDLINE
DCOM- 19880304
LR  - 20190812
IS  - 0001-6322 (Print)
IS  - 0001-6322 (Linking)
VI  - 75
IP  - 2
DP  - 1987
TI  - Axonal pathology of the skin in infantile neuroaxonal dystrophy.
PG  - 212-5
AB  - Ultrastructural studies on the skin of two patients affected by infantile 
      neuroaxonal dystrophy (INAD) were performed to evaluate its diagnostic value and 
      to discuss the etiology of INAD. While the majority of terminal axons around 
      intradermal glands were dystophic consisting of tubulomembranous and 
      tubulovesicular profiles sometimes accompanied by synaptic vesicles, there were 
      only few dystophic axons inside intradermal nerve bundles. These observations 
      suggest that the primary lesion of INAD is located in terminal and presynaptic 
      axons. Therefore, terminal axons have to be investigated when a diagnostic skin 
      biopsy is performed in INAD.
FAU - Kimura, S
AU  - Kimura S
AD  - Department of Pediatrics, Yokohama City University School of Medicine, Japan.
FAU - Sasaki, Y
AU  - Sasaki Y
FAU - Warlo, I
AU  - Warlo I
FAU - Goebel, H H
AU  - Goebel HH
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Germany
TA  - Acta Neuropathol
JT  - Acta neuropathologica
JID - 0412041
SB  - IM
MH  - Axons/*ultrastructure
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - Infant
MH  - Male
MH  - Nervous System Diseases/*pathology
MH  - Skin/*innervation
MH  - Sweat Glands/innervation
EDAT- 1987/01/01 00:00
MHDA- 1987/01/01 00:01
CRDT- 1987/01/01 00:00
PHST- 1987/01/01 00:00 [pubmed]
PHST- 1987/01/01 00:01 [medline]
PHST- 1987/01/01 00:00 [entrez]
AID - 10.1007/BF00687084 [doi]
PST - ppublish
SO  - Acta Neuropathol. 1987;75(2):212-5. doi: 10.1007/BF00687084.