PMID- 34343162
OWN - NLM
STAT- MEDLINE
DCOM- 20211223
LR  - 20230714
IS  - 1940-5480 (Electronic)
IS  - 1067-151X (Linking)
VI  - 30
IP  - 1
DP  - 2022 Jan 1
TI  - Impact of Prolonged Duration of Symptoms on Mental Health in Anterior Cervical 
      Disectomy and Fusion Patients.
PG  - e74-e82
LID - 10.5435/JAAOS-D-21-00050 [doi]
AB  - INTRODUCTION: Prolonged duration of symptoms is associated with worse pain and 
      disability in patients undergoing anterior cervical discectomy and fusion (ACDF). 
      Our study aims to determine the effect of symptom duration on severity of 
      depression among ACDF patients. METHODS: We retrospectively reviewed a 
      prospective surgical database from 2006 to 2019 for primary, single, or 
      multilevel ACDF. Patients missing the duration of symptom information or 
      patient-reported outcome measures (PROMs) were excluded. PROMs included Patient 
      Health Questionnaire-9, 12-Item Short Form Mental Component Score, and 12-Item 
      Veterans RAND Mental Component Score and were collected at preoperative, 6-week, 
      12-week, 6-month, 1-year, and 2-year timepoints. The minimum clinically important 
      difference (MCID) was calculated using the established values. Patients were 
      categorized based on preoperative duration of symptoms as follows: <6 months, >/=6 
      months and <1 year, 1 to 2 years, and >2 years. Univariate analysis was done to 
      determine differences in demographics and perioperative characteristics. 
      Intergroup differences in PROMs and MCID achievement were evaluated using linear 
      regression and logistic regression, respectively. RESULTS: Two hundred thirty-one 
      ACDF patients included had a mean age of 49.6 years and most were male (61.0%) 
      and nonobese (<30 kg/m2; 55.0%). The groups differed by their American Society of 
      Anesthesiologists classification (P = 0.029), workers' compensation status (P = 
      0.022), and diagnosis of herniated nucleus pulposus (P = 0.010). Postoperative 
      mental health outcomes did not significantly differ between duration groups 
      except for Veterans Rand-12 Mental Component Score at 12 weeks (P = 0.044). MCID 
      achievement rates did not significantly differ. CONCLUSION: Patients undergoing 
      ACDF largely did not demonstrate differences in mental health scores or 
      achievement of MCID based on the duration of symptoms.
CI  - Copyright (c) 2021 by the American Academy of Orthopaedic Surgeons.
FAU - Lynch, Conor P
AU  - Lynch CP
AUID- ORCID: 0000-0002-9554-2878
AD  - From the Department of Orthopaedic Surgery, Rush University Medical Center, 
      Chicago, IL.
FAU - Cha, Elliot D K
AU  - Cha EDK
AUID- ORCID: 0000-0001-8118-008
FAU - Mohan, Shruthi
AU  - Mohan S
FAU - Geoghegan, Cara E
AU  - Geoghegan CE
FAU - Jadczak, Caroline N
AU  - Jadczak CN
FAU - Singh, Kern
AU  - Singh K
AUID- ORCID: 0000-0002-6118-7273
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Am Acad Orthop Surg
JT  - The Journal of the American Academy of Orthopaedic Surgeons
JID - 9417468
SB  - IM
MH  - Cervical Vertebrae/surgery
MH  - Humans
MH  - Male
MH  - *Mental Health
MH  - Middle Aged
MH  - Prospective Studies
MH  - Retrospective Studies
MH  - *Spinal Fusion
MH  - Treatment Outcome
EDAT- 2021/08/04 06:00
MHDA- 2021/12/24 06:00
CRDT- 2021/08/03 17:21
PHST- 2021/01/12 00:00 [received]
PHST- 2021/07/04 00:00 [accepted]
PHST- 2021/08/04 06:00 [pubmed]
PHST- 2021/12/24 06:00 [medline]
PHST- 2021/08/03 17:21 [entrez]
AID - 00124635-202201010-00016 [pii]
AID - 10.5435/JAAOS-D-21-00050 [doi]
PST - ppublish
SO  - J Am Acad Orthop Surg. 2022 Jan 1;30(1):e74-e82. doi: 10.5435/JAAOS-D-21-00050.