PMID- 34345651
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220425
IS  - 2352-9067 (Print)
IS  - 2352-9067 (Electronic)
IS  - 2352-9067 (Linking)
VI  - 35
DP  - 2021 Aug
TI  - The potential impact of acute coronary syndromes on automatic sensing system in 
      Subcutaneous-ICDs.
PG  - 100841
LID - 10.1016/j.ijcha.2021.100841 [doi]
LID - 100841
AB  - BACKGROUND: The Subcutaneous-ICD (S-ICD) is emerging as a suitable option for 
      most ICD candidates, however some open issues regarding the sensing algorithm 
      still remain. OBJECTIVES: We aimed to examine the performance of the S-ICD 
      sensing algorithm in patients hospitalized for ST elevation myocardial infarction 
      (STEMI), non ST elevation acute coronary syndrome (NSTE-ACS) or chronic coronary 
      syndrome (CCS), before and after revascularization. METHODS: We performed a S-ICD 
      automated screening on 75 patients, 21 hospitalized for STEMI, 23 for NSTE-ACS 
      and 31 for CCS, before and after percutaneous revascularization, regardless their 
      eligibility to ICD implantation. RESULTS: Patients did not differ in clinical, 
      electrocardiographic and echocardiographic parameters. Rates of screening pass 
      were significantly lower in STEMI patients compared to NSTE-ACS and CCS (5% vs 
      56.7% vs 81% respectively, p < .0001). The viability of the primary vector was 
      lower in STEMI patients compared to NSTE-ACS and CCS (33% vs 56% vs 71%, p .027 
      respectively). After revascularization, there were no more significant 
      differences between groups. Pairing subjects at baseline and after 
      revascularization, STEMI subjects percentages of screening success were 
      respectively 5% and 81% (p < .001) and the rates of primary vector viability were 
      33% and 81% (p .002). STEMI was the only independent predictor of screening 
      failure at multivariate logistic regression analysis (odds ratio 10.68 confidence 
      interval 2.77-41.38, p = .001). CONCLUSION: The performance of the S-ICD and 
      possible malfunction detections in the context of an acute ischemic event deserve 
      further evaluation. Adequate patient selection and the development of dynamic 
      device programming are warranted.
CI  - (c) 2021 The Authors.
FAU - Narducci, M L
AU  - Narducci ML
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Scacciavillani, R
AU  - Scacciavillani R
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Pinnacchio, G
AU  - Pinnacchio G
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Bencardino, G
AU  - Bencardino G
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Perna, F
AU  - Perna F
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Comerci, G
AU  - Comerci G
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Campisi, M
AU  - Campisi M
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Ceccarelli, I
AU  - Ceccarelli I
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Pavone, C
AU  - Pavone C
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Spera, F
AU  - Spera F
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Bisignani, A
AU  - Bisignani A
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
FAU - Crea, F
AU  - Crea F
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
AD  - Cardiology Institute, Catholic University of Sacred Heart, Rome, Italy.
FAU - Pelargonio, G
AU  - Pelargonio G
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario 
      Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Roma, Italy.
AD  - Cardiology Institute, Catholic University of Sacred Heart, Rome, Italy.
LA  - eng
PT  - Journal Article
DEP - 20210720
PL  - Ireland
TA  - Int J Cardiol Heart Vasc
JT  - International journal of cardiology. Heart & vasculature
JID - 101649525
PMC - PMC8319739
OTO - NOTNLM
OT  - Acute coronary syndrome
OT  - Automated sensing system
OT  - CCS
OT  - S-ICD
OT  - STEMI
COIS- The authors report no relationships that could be construed as a conflict of 
      interest.
EDAT- 2021/08/05 06:00
MHDA- 2021/08/05 06:01
PMCR- 2021/07/20
CRDT- 2021/08/04 07:09
PHST- 2021/06/13 00:00 [received]
PHST- 2021/07/02 00:00 [revised]
PHST- 2021/07/05 00:00 [accepted]
PHST- 2021/08/04 07:09 [entrez]
PHST- 2021/08/05 06:00 [pubmed]
PHST- 2021/08/05 06:01 [medline]
PHST- 2021/07/20 00:00 [pmc-release]
AID - S2352-9067(21)00129-9 [pii]
AID - 100841 [pii]
AID - 10.1016/j.ijcha.2021.100841 [doi]
PST - epublish
SO  - Int J Cardiol Heart Vasc. 2021 Jul 20;35:100841. doi: 
      10.1016/j.ijcha.2021.100841. eCollection 2021 Aug.