PMID- 34349358 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210806 IS - 0968-7637 (Print) IS - 0968-7637 (Linking) VI - 28 IP - 3 DP - 2021 TI - People of color in North America report improvements in racial trauma and mental health symptoms following psychedelic experiences. PG - 215-226 LID - 10.1080/09687637.2020.1854688 [doi] AB - This study examined how psychedelics reduced symptoms of racial trauma among black, indigenous, and people of color (BIPOC) subsequent to an experience of racism. A cross-sectional internet-based survey included questions about experiences with racism, mental health symptoms, and acute and enduring psychedelic effects. Changes in mental health were assessed by retrospective report of symptoms in the 30 days before and 30 days after an experience with psilocybin, Lysergic acid diethylamide (LSD), or 3,4-Methylenedioxymethamphetamine (MDMA). We recruited 313 diverse BIPOC in the US and Canada. Results revealed a significant (p < .001) and moderate (d = -.45) reduction in traumatic stress symptoms from before-to-after the psychedelic experience. Similarly, participants reported decreases in depression (p < .001; d = -.52), anxiety (p < .001; d = -.53), and stress (p < .001; d = -.32). There was also a significant relationship (R(c) = 0.52, p < .001) between the dimension of acute psychedelic effects (mystical-type, insight, and challenging experiences) and decreases in a cluster of subsequent psychopathology (traumatic stress, depression, anxiety, and stress), while controlling for the frequency of prior discrimination and the time since the psychedelic experience. BIPOC have been underrepresented in psychedelic studies. Psychedelics may decrease the negative impact of racial trauma. Future studies should examine the efficacy of psychedelic-assisted therapy for individuals with a history of race-based trauma. FAU - Williams, Monnica T AU - Williams MT AUID- ORCID: 0000-0003-0095-3277 AD - School of Psychology, University of Ottawa, Ottawa, Canada. AD - Department of Psychological Sciences, University of Connecticut, Storrs, CT, USA. FAU - Davis, Alan K AU - Davis AK AD - College of Social Work, The Ohio State University, Columbus, OH, USA. AD - Center for Psychedelic and Consciousness Research, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA. FAU - Xin, Yitong AU - Xin Y AD - College of Social Work, The Ohio State University, Columbus, OH, USA. FAU - Sepeda, Nathan D AU - Sepeda ND AD - Center for Psychedelic and Consciousness Research, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA. FAU - Grigas, Pamela Colomicronn AU - Grigas PC AD - Department of Psychological Sciences, University of Connecticut, Storrs, CT, USA. FAU - Sinnott, Sinead AU - Sinnott S AD - Department of Psychological Sciences, University of Connecticut, Storrs, CT, USA. FAU - Haeny, Angela M AU - Haeny AM AD - Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA. LA - eng GR - R25 DA035163/DA/NIDA NIH HHS/United States GR - T32 DA019426/DA/NIDA NIH HHS/United States GR - UL1 TR001863/TR/NCATS NIH HHS/United States PT - Journal Article DEP - 20201210 PL - England TA - Drugs (Abingdon Engl) JT - Drugs (Abingdon, England) JID - 9515845 PMC - PMC8330400 MID - NIHMS1664570 OTO - NOTNLM OT - Psychedelics OT - ethnic minorities OT - hallucinogens OT - people of color OT - racial trauma OT - substance use EDAT- 2021/08/06 06:00 MHDA- 2021/08/06 06:01 PMCR- 2021/08/03 CRDT- 2021/08/05 06:21 PHST- 2021/08/05 06:21 [entrez] PHST- 2021/08/06 06:00 [pubmed] PHST- 2021/08/06 06:01 [medline] PHST- 2021/08/03 00:00 [pmc-release] AID - 10.1080/09687637.2020.1854688 [doi] PST - ppublish SO - Drugs (Abingdon Engl). 2021;28(3):215-226. doi: 10.1080/09687637.2020.1854688. Epub 2020 Dec 10.