PMID- 34351024
OWN - NLM
STAT- MEDLINE
DCOM- 20220404
LR  - 20220405
IS  - 1365-2303 (Electronic)
IS  - 0956-5507 (Linking)
VI  - 33
IP  - 1
DP  - 2022 Jan
TI  - Follicular dendritic cell sarcoma of the cervical lymph node diagnosed on fine 
      needle aspiration cytology.
PG  - 119-122
LID - 10.1111/cyt.13047 [doi]
AB  - Follicular dendritic cell sarcomas (FDCS) are rare tumours of lymph nodes and 
      extranodal tissues which are grouped with the histiocytic and dendritic cell 
      neoplasms. The diagnosis is usually made after thorough clinical and pathological 
      examination with immunohistochemical analysis. Difficulties persist in diagnosing 
      FDCS on cytological preparations. We report herein a case of a 57-year-old female 
      who presented with a right neck mass of 5 months duration. Computed Tomography 
      (CT) imaging of the neck reported a necrotic right level IIb lymph node and 
      asymmetric fullness of the right palatine tonsil. Fine needle aspiration (FNA) 
      biopsy revealed numerous spindle, oval and stellate neoplastic cells, arranged 
      singly and in syncytia with moderate nuclear pleomorphism, vesicular chromatin 
      pattern, and prominent nucleoli, sprinkled with small lymphocytes. The tumour 
      cells were strongly diffusely positive for CD21, CD23, and D2-40 immunostaining 
      on cell bock sections, but were negative for CD1a and CD34, supporting the 
      diagnosis of FDCS. Follow-up surgical pathology on the resection showed 
      histopathological features and an immunohistochemical profile consistent with 
      FDCS.
CI  - (c) 2021 John Wiley & Sons Ltd.
FAU - Xia, Rong
AU  - Xia R
AUID- ORCID: 0000-0001-8573-2152
AD  - Department of Pathology, New York University Langone Health, New York, NY, USA.
FAU - Shafizadeh, Negin
AU  - Shafizadeh N
AD  - Department of Pathology, New York University Langone Health, New York, NY, USA.
FAU - Brandler, Tamar
AU  - Brandler T
AD  - Department of Pathology, New York University Langone Health, New York, NY, USA.
FAU - Liu, Cheng
AU  - Liu C
AD  - Department of Pathology, New York University Langone Health, New York, NY, USA.
FAU - Oweity, Thaira
AU  - Oweity T
AD  - Department of Pathology, New York University Langone Health, New York, NY, USA.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20210830
PL  - England
TA  - Cytopathology
JT  - Cytopathology : official journal of the British Society for Clinical Cytology
JID - 9010345
SB  - IM
MH  - Biopsy, Fine-Needle/methods
MH  - *Dendritic Cell Sarcoma, Follicular/diagnosis/pathology
MH  - Female
MH  - Humans
MH  - Lymph Nodes/pathology
MH  - Middle Aged
MH  - Neck/pathology
MH  - *Sarcoma/pathology
OTO - NOTNLM
OT  - CD21
OT  - CD23
OT  - fine needle aspiration cytology
OT  - follicular dendritic cell sarcoma
OT  - neck swelling
EDAT- 2021/08/06 06:00
MHDA- 2022/04/05 06:00
CRDT- 2021/08/05 08:53
PHST- 2021/07/07 00:00 [revised]
PHST- 2021/04/11 00:00 [received]
PHST- 2021/08/02 00:00 [accepted]
PHST- 2021/08/06 06:00 [pubmed]
PHST- 2022/04/05 06:00 [medline]
PHST- 2021/08/05 08:53 [entrez]
AID - 10.1111/cyt.13047 [doi]
PST - ppublish
SO  - Cytopathology. 2022 Jan;33(1):119-122. doi: 10.1111/cyt.13047. Epub 2021 Aug 30.