PMID- 34364281
OWN - NLM
STAT- MEDLINE
DCOM- 20211019
LR  - 20211019
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 799
DP  - 2021 Dec 10
TI  - Health risk assessment and development of human health ambient water quality 
      criteria for PBDEs in China.
PG  - 149353
LID - S0048-9697(21)04426-0 [pii]
LID - 10.1016/j.scitotenv.2021.149353 [doi]
AB  - Polybrominated diphenyl ethers (PBDEs) are not only a class of highly efficient 
      brominated flame retardants (BFRs) but also a class of typical persistent organic 
      pollutants (POPs) that are persistent and widely distributed in various 
      environmental media. This study examined the concentrations of PBDEs in five 
      environmental media (water, soil, air, dust, and food) and two human body media 
      (human milk and blood) in China from 2010 to 2020. In addition, this study 
      conducted multi-pathway exposure health risk assessments of populations of 
      different ages in urban, rural, key regions, and industrial factories using the 
      Monte-Carlo simulation. Finally, the human health ambient water quality criteria 
      (AWQC) of eight PBDEs were derived using Chinese exposure parameters and 
      bioaccumulation factors (BAFs). The results showed that the eastern and 
      southeastern coastal regions of China were heavily polluted by PBDEs, and the 
      variation trends of the SigmaPBDEs concentrations in the different exposure media 
      were not consistent. PBDEs did not pose a risk to urban and rural residents in 
      ordinary regions, but the hazard indexes (HIs) for residents in key regions and 
      occupational workers exceeded the safety threshold. Dust exposure was the primary 
      exposure pathway for urban and rural residents in ordinary regions, but for 
      residents in key regions and occupational workers, dietary exposure was the 
      primary exposure pathway. BDE-209 was found to be the most serious individual 
      PBDE congener in China. The following human health AWQC values of the PBDEs were 
      derived: drinking water exposure: 0.233-65.2 mug.L(-1); and drinking water and 
      aquatic products exposure: 8.51 x 10(-4)-1.10 mug.L(-1).
CI  - Copyright (c) 2021 Elsevier B.V. All rights reserved.
FAU - Wang, Jing
AU  - Wang J
AD  - State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese 
      Research Academy of Environmental Sciences, Beijing 100012, PR China; College of 
      Marine Ecology and Environment, Shanghai Ocean University, Shanghai 201306, PR 
      China.
FAU - Yan, Zhenguang
AU  - Yan Z
AD  - State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese 
      Research Academy of Environmental Sciences, Beijing 100012, PR China. Electronic 
      address: zgyan@craes.org.cn.
FAU - Zheng, Xin
AU  - Zheng X
AD  - State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese 
      Research Academy of Environmental Sciences, Beijing 100012, PR China.
FAU - Wang, Shuping
AU  - Wang S
AD  - State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese 
      Research Academy of Environmental Sciences, Beijing 100012, PR China.
FAU - Fan, Juntao
AU  - Fan J
AD  - State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese 
      Research Academy of Environmental Sciences, Beijing 100012, PR China.
FAU - Sun, Qianhang
AU  - Sun Q
AD  - State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese 
      Research Academy of Environmental Sciences, Beijing 100012, PR China.
FAU - Xu, Jiayun
AU  - Xu J
AD  - State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese 
      Research Academy of Environmental Sciences, Beijing 100012, PR China.
FAU - Men, Shuhui
AU  - Men S
AD  - State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese 
      Research Academy of Environmental Sciences, Beijing 100012, PR China.
LA  - eng
PT  - Journal Article
DEP - 20210730
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Dust)
RN  - 0 (Flame Retardants)
RN  - 0 (Halogenated Diphenyl Ethers)
SB  - IM
MH  - China
MH  - Dust/analysis
MH  - Environmental Exposure/analysis
MH  - Environmental Monitoring
MH  - *Flame Retardants/analysis
MH  - *Halogenated Diphenyl Ethers/analysis
MH  - Humans
MH  - Risk Assessment
MH  - Water Quality
OTO - NOTNLM
OT  - AWQC
OT  - Human health
OT  - Multi-pathway exposure
OT  - PBDEs
OT  - Risk assessment
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2021/08/08 06:00
MHDA- 2021/10/21 06:00
CRDT- 2021/08/07 20:29
PHST- 2021/05/25 00:00 [received]
PHST- 2021/07/17 00:00 [revised]
PHST- 2021/07/26 00:00 [accepted]
PHST- 2021/08/08 06:00 [pubmed]
PHST- 2021/10/21 06:00 [medline]
PHST- 2021/08/07 20:29 [entrez]
AID - S0048-9697(21)04426-0 [pii]
AID - 10.1016/j.scitotenv.2021.149353 [doi]
PST - ppublish
SO  - Sci Total Environ. 2021 Dec 10;799:149353. doi: 10.1016/j.scitotenv.2021.149353. 
      Epub 2021 Jul 30.