PMID- 34371467
OWN - NLM
STAT- MEDLINE
DCOM- 20210916
LR  - 20220531
IS  - 1751-732X (Electronic)
IS  - 1751-7311 (Linking)
VI  - 15
IP  - 9
DP  - 2021 Sep
TI  - Effect of chromium methionine supplementation on lactation performance, hepatic 
      respiratory rate and anti-oxidative capacity in early-lactating dairy cows.
PG  - 100326
LID - S1751-7311(21)00169-5 [pii]
LID - 10.1016/j.animal.2021.100326 [doi]
AB  - Chromium may regulate dairy cow metabolism; a chelated formation of chromium 
      methionine (Cr-Met) is available to the feed industry. The objective of this 
      study was to investigate the effect of Cr-Met supplementation on lactation 
      performance, hepatic respiratory rate and anti-oxidative capacity in 
      early-lactating Holstein dairy cows. 64 multiparous cows were assigned to 16 
      blocks based on parity and milk yield and then the four cows in a block were 
      randomly allocated to four treatment groups with 0, 4, 8 or 16 g/d of Cr-Met per 
      cow supplemented to a basal diet. Cows were moved from an open dry lot to a 
      naturally ventilated tie stall barn 2 weeks before treatment to adapt to this 
      facility, fed and milked at 0630, 1400, and 1930 h every day. The experiment 
      lasted for 12 weeks. Milk yield and composition were recorded weekly. Dry matter 
      intake was measured every 2 weeks for a total of six times throughout the trial. 
      The plasma variables were measured in weeks 4, 8 and 12 of the experiment. 
      Supplementation of Cr-Met did not affect DM intake of cows. As the 
      supplementation of Cr-Met increased, yields of milk, fat, energy corrected milk 
      (P < 0.01) and lactose (P = 0.01) increased in a linear manner. In terms of 
      plasma variables, insulin concentration decreased in a linear manner with Cr-Met 
      supplementation. As for variables relating to hepatic respiration rate, 
      concentrations of pyruvate and NAD in the plasma were increased in quadratic 
      manners, and lactic dehydrogenase activity was linearly increased as Cr-Met 
      feeding levels increased. Moreover, plasma glutathione peroxidase and superoxide 
      dismutase activity were increased in a linear manner. In conclusion, our study 
      suggested that Cr-Met supplementation improved lactation performance of 
      early-lactating dairy cows through enhancing antioxidant capacity and hepatic 
      cellular respiration.
CI  - Copyright (c) 2021 The Author(s). Published by Elsevier B.V. All rights reserved.
FAU - Wu, Z Z
AU  - Wu ZZ
AD  - Institute of Dairy Science, MoE Key Laboratory of Molecular Animal Nutrition, 
      College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China.
FAU - Peng, W C
AU  - Peng WC
AD  - Institute of Dairy Science, MoE Key Laboratory of Molecular Animal Nutrition, 
      College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China.
FAU - Liu, J X
AU  - Liu JX
AD  - Institute of Dairy Science, MoE Key Laboratory of Molecular Animal Nutrition, 
      College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China.
FAU - Xu, G Z
AU  - Xu GZ
AD  - Zinpro Corporation, Eden Prairie, MN 55344, United States.
FAU - Wang, D M
AU  - Wang DM
AD  - Institute of Dairy Science, MoE Key Laboratory of Molecular Animal Nutrition, 
      College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China. 
      Electronic address: wdm@zju.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial, Veterinary
DEP - 20210807
PL  - England
TA  - Animal
JT  - Animal : an international journal of animal bioscience
JID - 101303270
RN  - 0R0008Q3JB (Chromium)
RN  - AE28F7PNPL (Methionine)
SB  - IM
MH  - Animals
MH  - Cattle
MH  - Chromium
MH  - Diet/veterinary
MH  - Dietary Supplements
MH  - Female
MH  - *Lactation
MH  - *Methionine
MH  - Milk
MH  - Pregnancy
MH  - Respiratory Rate
OTO - NOTNLM
OT  - Chromium chelate
OT  - Early lactation
OT  - Holstein cows
OT  - Metabolism
OT  - Production performance
EDAT- 2021/08/10 06:00
MHDA- 2021/09/18 06:00
CRDT- 2021/08/09 20:28
PHST- 2020/09/06 00:00 [received]
PHST- 2021/06/25 00:00 [revised]
PHST- 2021/06/28 00:00 [accepted]
PHST- 2021/08/10 06:00 [pubmed]
PHST- 2021/09/18 06:00 [medline]
PHST- 2021/08/09 20:28 [entrez]
AID - S1751-7311(21)00169-5 [pii]
AID - 10.1016/j.animal.2021.100326 [doi]
PST - ppublish
SO  - Animal. 2021 Sep;15(9):100326. doi: 10.1016/j.animal.2021.100326. Epub 2021 Aug 
      7.