PMID- 34373144
OWN - NLM
STAT- MEDLINE
DCOM- 20211101
LR  - 20211101
IS  - 1878-7533 (Electronic)
IS  - 1550-7289 (Linking)
VI  - 17
IP  - 11
DP  - 2021 Nov
TI  - Impact of a severe complication two years after laparoscopic Roux-en-Y gastric 
      bypass: a cohort study from the Scandinavian Obesity Surgery Registry.
PG  - 1874-1882
LID - S1550-7289(21)00336-1 [pii]
LID - 10.1016/j.soard.2021.06.023 [doi]
AB  - BACKGROUND: Although severe complications (SCs) after laparoscopic Roux-en-Y 
      gastric bypass (LRYGB) are rare, they can be devastating for the affected 
      patient. OBJECTIVE: To access the impact of SCs (Clavien-Dindo >/=3b) 2 years after 
      LRYGB by using a nationwide Swedish cohort of 48,201 primary cases between 2007 
      and June 2016. SETTING: University hospital, Sweden. METHODS: Patients with SC 
      were matched 1:1 on age, sex, diabetic status, body mass index (BMI), and year of 
      operation to patients without an SC. Weight loss, patient-scored quality of life 
      (QoL), antidepressant use, proton pump inhibitors (PPI) and opioids, and 
      in-hospital care were gathered from 3 national registers. RESULTS: A total of 
      1411 (2.9%) patients suffered an SC and 16 (.03%) died. In total, 1403 patients 
      with SC (mean age, 42 yr; female, 75%; with diabetes, 15.7%; mean BMI, 41.9 
      kg/m(2)) could be matched. Both groups had a total body weight loss of 32% at 2 
      years. A lower physical QoL was observed in SCs throughout the study period. 
      Antidepressant, PPI and opioid use was higher among patients with SC, even 2 
      years after surgery. At this time point, a doubling of oral morphine equivalents 
      (7.3 to 17.0 mg/d) was found in patients with SC compared with prior to surgery. 
      The SC group required more in-hospital care after the initial 30 days (3.8 versus 
      .9 d in the remaining part of the first year). CONCLUSION: An SC resulted in 
      higher antidepressant, PPI and opioid use as well as higher need for in-hospital 
      care during the first 2 postoperative years. Affected patients should therefore 
      receive special attention during follow up.
CI  - Copyright (c) 2021 American Society for Bariatric Surgery. Published by Elsevier 
      Inc. All rights reserved.
FAU - Vidarsson, Bjarni
AU  - Vidarsson B
AD  - Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. Electronic 
      address: bjarni.vidarsson@surgsci.uu.se.
FAU - Lofling Skogar, Martin
AU  - Lofling Skogar M
AD  - Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
FAU - Sundbom, Magnus
AU  - Sundbom M
AD  - Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
LA  - eng
PT  - Journal Article
DEP - 20210706
PL  - United States
TA  - Surg Obes Relat Dis
JT  - Surgery for obesity and related diseases : official journal of the American 
      Society for Bariatric Surgery
JID - 101233161
SB  - IM
CIN - Surg Obes Relat Dis. 2021 Nov;17(11):1882-1883. PMID: 34481725
MH  - Adult
MH  - Body Mass Index
MH  - Cohort Studies
MH  - Female
MH  - *Gastric Bypass/adverse effects
MH  - Humans
MH  - *Laparoscopy
MH  - *Obesity, Morbid/surgery
MH  - Postoperative Complications/epidemiology/etiology
MH  - Quality of Life
MH  - Registries
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Co-morbidities
OT  - Complications
OT  - Gastric bypass
OT  - Healthcare consumption
OT  - LRYGB
OT  - Quality of life
OT  - Roux-en-Y gastric bypass
OT  - SF-36
EDAT- 2021/08/11 06:00
MHDA- 2021/11/03 06:00
CRDT- 2021/08/10 05:46
PHST- 2021/04/08 00:00 [received]
PHST- 2021/06/09 00:00 [revised]
PHST- 2021/06/26 00:00 [accepted]
PHST- 2021/08/11 06:00 [pubmed]
PHST- 2021/11/03 06:00 [medline]
PHST- 2021/08/10 05:46 [entrez]
AID - S1550-7289(21)00336-1 [pii]
AID - 10.1016/j.soard.2021.06.023 [doi]
PST - ppublish
SO  - Surg Obes Relat Dis. 2021 Nov;17(11):1874-1882. doi: 10.1016/j.soard.2021.06.023. 
      Epub 2021 Jul 6.