PMID- 34377136 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220425 IS - 1642-395X (Print) IS - 2299-0046 (Electronic) IS - 1642-395X (Linking) VI - 38 IP - 3 DP - 2021 Jun TI - Depressive, anxiety, stress, and insomnia symptoms in patients with psoriasis: a cross-sectional study. PG - 510-519 LID - 10.5114/ada.2020.98726 [doi] AB - INTRODUCTION: Assessment of psychological well-being in psoriasis patients is recommended. However, studies evaluating depressive, anxiety, stress, and insomnia symptoms in Arabic patients with psoriasis are lacking. AIM: To quantify levels of psoriasis-related depressive, anxiety, stress, and insomnia symptoms in Arabic patients with psoriasis. MATERIAL AND METHODS: A cross-sectional survey on patients' demographics, disease characteristics, and psychological measures using the Patient Health Questionnaire-9, Generalized Anxiety Disorder 7-item scale, Depression Anxiety Stress Scale-21 (7-item stress subscale), and Insomnia Severity Index. The prevalence and scores of depressive, anxiety, stress, and insomnia symptoms were calculated. Multivariate linear regression models were developed to assess patients' demographics and disease characteristics affecting the psychological measures. RESULTS: The analysis included 223 patients. The patients reported mild levels of depressive, anxiety, and insomnia symptoms (median (interquartile range (IQR)) scores: 9 (6-14), 6 (4-11), and 12 (4-18), respectively) and a moderate level of stress symptoms (median (IQR) score: 10 (5-14)). The prevalence of depressive, anxiety, stress, and insomnia symptoms were 47.1%, 32.7%, 59.6%, and 57%, respectively. Multivariate linear regression analyses revealed that for each unit increase in the impact of psoriasis on daily life, there were 5.7 (95% confidence intervals (CI): 3.7-7.8), 3.8 (95% CI: 1.8-5.7), 5.3 (95% CI: 3.1-7.4), and 6.5 (95% CI: 3.7-9.4) units increase in depression, anxiety, and stress, and insomnia scores, respectively. CONCLUSIONS: The prevalence of depressive, anxiety, stress, and insomnia symptoms in Arabic patients with psoriasis was high. Clinical interventions, screening for psychiatric comorbidities, and consideration of psychotherapy should be implemented in this patient group. CI - Copyright: (c) 2021 Termedia Sp. z o. o. FAU - Soliman, Moetaza M AU - Soliman MM AD - Department of Pharmacy Practice, Faculty of Pharmacy, Mansoura University, Egypt. LA - eng PT - Journal Article DEP - 20200918 PL - Poland TA - Postepy Dermatol Alergol JT - Postepy dermatologii i alergologii JID - 101168357 PMC - PMC8330873 OTO - NOTNLM OT - anxiety OT - cross-sectional OT - depression OT - insomnia OT - psoriasis OT - stress COIS- The author declares no conflict of interest. EDAT- 2021/08/12 06:00 MHDA- 2021/08/12 06:01 PMCR- 2021/06/01 CRDT- 2021/08/11 06:36 PHST- 2020/06/25 00:00 [received] PHST- 2020/08/05 00:00 [accepted] PHST- 2021/08/11 06:36 [entrez] PHST- 2021/08/12 06:00 [pubmed] PHST- 2021/08/12 06:01 [medline] PHST- 2021/06/01 00:00 [pmc-release] AID - 98726 [pii] AID - 10.5114/ada.2020.98726 [doi] PST - ppublish SO - Postepy Dermatol Alergol. 2021 Jun;38(3):510-519. doi: 10.5114/ada.2020.98726. Epub 2020 Sep 18.