PMID- 34383200
OWN - NLM
STAT- MEDLINE
DCOM- 20220629
LR  - 20220817
IS  - 1573-2568 (Electronic)
IS  - 0163-2116 (Linking)
VI  - 67
IP  - 7
DP  - 2022 Jul
TI  - Adverse Events Associated with Routine Colonoscopy in Patients with End-Stage 
      Renal Disease.
PG  - 3158-3165
LID - 10.1007/s10620-021-07137-5 [doi]
AB  - BACKGROUND AND AIM: Although colonoscopy has been widely performed in patients 
      with end-stage renal disease (ESRD), studies on the safety of routine 
      colonoscopy, including bowel preparation and sedation, in these patients are 
      limited. This study aimed to investigate the safety of colonoscopy in patients 
      with ESRD who underwent peritoneal dialysis (PD) or hemodialysis (HD). METHODS: 
      We retrospectively reviewed 538 patients with ESRD who underwent colonoscopy 
      between 2010 and 2020. We compared the incidence of adverse events (AEs) between 
      the ESRD group and a propensity score-matched control group of healthy adults. 
      Cardiovascular/pulmonary and procedure-related AEs were analyzed. We also 
      compared the rates of AEs between patients who underwent PD or HD. RESULTS: The 
      overall rate of AEs was 5.7% in patients with ESRD, which was significantly 
      higher than that in healthy adults (0.6%, P < 0.001). All AEs were 
      cardiovascular/pulmonary in nature, but no perforation or bleeding occurred. Most 
      AEs were not severe and resolved with medical treatment. The incidence of AEs was 
      higher in the HD group than in the PD group, but the difference was not 
      significant (6.1% vs. 3.5%, respectively, P = 0.451). In the HD group, patients 
      with AEs were significantly older than those without AEs (P = 0.009). 
      CONCLUSIONS: The rate of colonoscopy-related AEs in patients with ESRD on 
      dialysis was higher than that in healthy adults, but most AEs were not severe. 
      Routine colonoscopy may be safely performed in patients with ESRD regardless of 
      the method of dialysis, but more carefully in older patients on HD.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Goong, Hyeon Jeong
AU  - Goong HJ
AD  - Department of Internal Medicine, Digestive Disease Center and Research Institute, 
      Soonchunhyang University School of Medicine, Soonchunhyang University Bucheon 
      Hospital, 170 Jomaru-ro, Wonmi-gu, Bucheon, 420-767, Republic of Korea.
FAU - Ko, Bong Min
AU  - Ko BM
AUID- ORCID: 0000-0002-0635-4454
AD  - Department of Internal Medicine, Digestive Disease Center and Research Institute, 
      Soonchunhyang University School of Medicine, Soonchunhyang University Bucheon 
      Hospital, 170 Jomaru-ro, Wonmi-gu, Bucheon, 420-767, Republic of Korea. 
      kopa9445@schmc.ac.kr.
FAU - Lee, Moon Sung
AU  - Lee MS
AD  - Department of Internal Medicine, Digestive Disease Center and Research Institute, 
      Soonchunhyang University School of Medicine, Soonchunhyang University Bucheon 
      Hospital, 170 Jomaru-ro, Wonmi-gu, Bucheon, 420-767, Republic of Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210812
PL  - United States
TA  - Dig Dis Sci
JT  - Digestive diseases and sciences
JID - 7902782
SB  - IM
MH  - Adult
MH  - Aged
MH  - Colonoscopy/adverse effects
MH  - Humans
MH  - *Kidney Failure, Chronic/complications/diagnosis/therapy
MH  - *Peritoneal Dialysis/adverse effects
MH  - Renal Dialysis/adverse effects
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Colonoscopy
OT  - End-stage renal disease
OT  - Hemodialysis
OT  - Peritoneal dialysis
EDAT- 2021/08/13 06:00
MHDA- 2022/06/30 06:00
CRDT- 2021/08/12 12:32
PHST- 2021/03/26 00:00 [received]
PHST- 2021/06/24 00:00 [accepted]
PHST- 2021/08/13 06:00 [pubmed]
PHST- 2022/06/30 06:00 [medline]
PHST- 2021/08/12 12:32 [entrez]
AID - 10.1007/s10620-021-07137-5 [pii]
AID - 10.1007/s10620-021-07137-5 [doi]
PST - ppublish
SO  - Dig Dis Sci. 2022 Jul;67(7):3158-3165. doi: 10.1007/s10620-021-07137-5. Epub 2021 
      Aug 12.