PMID- 34390250
OWN - NLM
STAT- MEDLINE
DCOM- 20211125
LR  - 20211125
IS  - 1600-0404 (Electronic)
IS  - 0001-6314 (Linking)
VI  - 144
IP  - 6
DP  - 2021 Dec
TI  - Functional neuroimaging in nonepileptiform electroencephalographic patterns in 
      status epilepticus.
PG  - 687-694
LID - 10.1111/ane.13515 [doi]
AB  - BACKGROUND: The diagnosis of nonconvulsive status epilepticus (NCSE) in patients 
      with nonepileptiform EEG patterns remains a challenge. OBJECTIVE: To evaluate the 
      usefulness of single photon emission computerized tomography (SPECT) and its 
      quantification (QtSPECT) in the diagnosis of NCSE. METHODS: We retrospectively 
      reviewed patients admitted with clinical suspicion of NCSE who underwent an 
      HMPAO-SPECT simultaneously with scalp EEG showing nonepileptiform patterns, in a 
      5-year period. After a complete diagnostic workup, treatment, and clinical 
      evolution, disregarding the SPECT results, patients were classified into 
      confirmed NCSE (n = 11) and non-NCSE (n = 8). Then, we compared the EEG and SPECT 
      results in both groups. RESULTS: Lateralized rhythmic delta activity (LRDA) was 
      predominant in the NCSE group (45.4%, p = .045), while lateralized irregular 
      slowing was observed equally in both groups. Patients with NCSE showed 
      significant hyperperfusion compared with non-NCSE patients (p = .026). QtSPECT 
      correctly classified 91% of patients in NCSE and 75% patients with non-NCSE 
      (p = .006). CONCLUSIONS: Regional cerebral blood flow measured with SPECT could 
      be useful in the diagnosis of NCSE in cases of an EEG pattern with lateralized 
      slow activity and high clinical suspicion.
CI  - (c) 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Munoz-Vendrell, Albert
AU  - Munoz-Vendrell A
AUID- ORCID: 0000-0001-8221-865X
AD  - Neurology Service, Epilepsy Unit, Hospital Universitari de Bellvitge-IDIBELL, 
      Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.
FAU - Sala-Padro, Jacint
AU  - Sala-Padro J
AD  - Neurology Service, Epilepsy Unit, Hospital Universitari de Bellvitge-IDIBELL, 
      Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.
FAU - Jaraba, Sonia
AU  - Jaraba S
AD  - Neurology Service, Epilepsy Unit, Hospital Universitari de Bellvitge-IDIBELL, 
      Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.
AD  - Neurology Department, Hospital de Viladecans, Viladecans, Barcelona, Spain.
FAU - Reynes-Llompart, Gabriel
AU  - Reynes-Llompart G
AD  - Medical Physics Department, Institut Catala d'Oncologia, L'Hospitalet de 
      Llobregat, Barcelona, Spain.
AD  - Image Diagnostic Institute (IDI), Nuclear Medicine Department, SPECT Unit, 
      Hospital Universitari de Bellvitge, Image Diagnostic Institute, L'Hospitalet de 
      Llobregat, Barcelona, Spain.
FAU - Veciana, Misericordia
AU  - Veciana M
AD  - Neurology Service, Neurophysiology Department, Hospital Universitari de 
      Bellvitge-IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, 
      Barcelona, Spain.
FAU - Mora, Jaume
AU  - Mora J
AD  - Image Diagnostic Institute (IDI), Nuclear Medicine Department, SPECT Unit, 
      Hospital Universitari de Bellvitge, Image Diagnostic Institute, L'Hospitalet de 
      Llobregat, Barcelona, Spain.
FAU - Falip, Merce
AU  - Falip M
AD  - Neurology Service, Epilepsy Unit, Hospital Universitari de Bellvitge-IDIBELL, 
      Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.
LA  - eng
PT  - Journal Article
DEP - 20210814
PL  - Denmark
TA  - Acta Neurol Scand
JT  - Acta neurologica Scandinavica
JID - 0370336
SB  - IM
MH  - Electroencephalography
MH  - Functional Neuroimaging
MH  - Humans
MH  - Retrospective Studies
MH  - *Status Epilepticus/diagnostic imaging
MH  - Tomography, Emission-Computed, Single-Photon
OTO - NOTNLM
OT  - SPECT
OT  - ictal-interictal continuum
OT  - lateralized rhythmic delta activity
OT  - nonconvulsive status epilepticus
OT  - quantified SPECT
EDAT- 2021/08/15 06:00
MHDA- 2021/11/26 06:00
CRDT- 2021/08/14 08:34
PHST- 2021/07/22 00:00 [revised]
PHST- 2021/04/20 00:00 [received]
PHST- 2021/07/29 00:00 [accepted]
PHST- 2021/08/15 06:00 [pubmed]
PHST- 2021/11/26 06:00 [medline]
PHST- 2021/08/14 08:34 [entrez]
AID - 10.1111/ane.13515 [doi]
PST - ppublish
SO  - Acta Neurol Scand. 2021 Dec;144(6):687-694. doi: 10.1111/ane.13515. Epub 2021 Aug 
      14.