PMID- 34394223
OWN - NLM
STAT- MEDLINE
DCOM- 20211021
LR  - 20220425
IS  - 1729-0503 (Electronic)
IS  - 1680-6905 (Print)
IS  - 1680-6905 (Linking)
VI  - 20
IP  - 4
DP  - 2020 Dec
TI  - Prevalence of Helicobacter pylori infection among children with primary nephrotic 
      syndrome: a cross-sectional study.
PG  - 1624-1631
LID - 10.4314/ahs.v20i4.15 [doi]
AB  - BACKGROUND: Limited data are available about the prevalence of helicobacter 
      pylori (H.pylori) infection among primary NS children. OBJECTIVES: To assess the 
      frequency and risk factors of H.pylori infection among children with primary NS. 
      METHODS: A cross-sectional study was carried out in Mansoura University 
      Children's Hospital, Egypt during the period from 2017 to 2019 including 100 NS 
      children (NS group) and 100 healthy controls. NS group included 88 steroid 
      sensitive (SSNS) and 12 steroid resistant (SRNS) cases. All patients were 
      assessed for H.pylori infection using H.pylori stool antigen (HpSA) test. 
      Statistical analysis was done using chi-square, fisher exact and Mann-Whitney 
      tests. RESULTS: With regard to HpSA test results, no significant differences were 
      detected between control and NS groups (p = 0.193) and between SSNS and SRNS 
      groups (p = 0.286). Concerning total biopsied cases and MCD (proven plus 
      presumed) cases, no significant differences were found between those with 
      positive and negative HpSA test (p = 0.648 and 0.126, respectively). The high 
      dose of steroid therapy was associated with a higher risk of H.pylori infection 
      among NS group (Odds ratio = 3.8; 95% confidence interval = 1.3-11.3). 
      CONCLUSION: The current study negates the increased risk of H.pylori infection in 
      children with primary NS.
CI  - (c) 2020 Mahmoud A et al.
FAU - Mahmoud, Ahmed
AU  - Mahmoud A
AD  - Mansoura University, Faculty of Medicine, Department of Pediatrics.
FAU - Bakr, Ashraf
AU  - Bakr A
AD  - Mansoura University, Faculty of Medicine, Department of Pediatrics.
FAU - Elsaid, Afaf
AU  - Elsaid A
AD  - Mansoura University Children's Hospital, Biochemistry Section.
FAU - Wahba, Yahya
AU  - Wahba Y
AD  - Mansoura University, Faculty of Medicine, Department of Pediatrics.
LA  - eng
PT  - Journal Article
PL  - Uganda
TA  - Afr Health Sci
JT  - African health sciences
JID - 101149451
RN  - 0 (Antigens, Bacterial)
SB  - IM
MH  - Adolescent
MH  - Antigens, Bacterial/*analysis
MH  - Child
MH  - Child, Preschool
MH  - Cross-Sectional Studies
MH  - Egypt/epidemiology
MH  - Feces/chemistry/*microbiology
MH  - Female
MH  - Helicobacter Infections/diagnosis/*epidemiology
MH  - Helicobacter pylori/*isolation & purification
MH  - Humans
MH  - Male
MH  - Nephrotic Syndrome/*complications/epidemiology
MH  - Prevalence
PMC - PMC8351824
OTO - NOTNLM
OT  - Children
OT  - H.pylori
OT  - primary nephrotic syndrome
EDAT- 2021/08/17 06:00
MHDA- 2022/04/26 06:00
PMCR- 2020/12/01
CRDT- 2021/08/16 05:49
PHST- 2021/08/16 05:49 [entrez]
PHST- 2021/08/17 06:00 [pubmed]
PHST- 2022/04/26 06:00 [medline]
PHST- 2020/12/01 00:00 [pmc-release]
AID - jAFHS.v20.i4.pg1624 [pii]
AID - 10.4314/ahs.v20i4.15 [doi]
PST - ppublish
SO  - Afr Health Sci. 2020 Dec;20(4):1624-1631. doi: 10.4314/ahs.v20i4.15.