PMID- 34401593 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240403 IS - 2405-8440 (Print) IS - 2405-8440 (Electronic) IS - 2405-8440 (Linking) VI - 7 IP - 8 DP - 2021 Aug TI - Cardiovascular risk assessment among type-2 diabetic subjects in selected areas of Bangladesh: concordance among without cholesterol-based WHO/ISH, Globorisk, and Framingham risk prediction tools. PG - e07728 LID - 10.1016/j.heliyon.2021.e07728 [doi] LID - e07728 AB - INTRODUCTION: Cardiovascular disease (CVD) risk is higher among the subjects with type-2 diabetes mellitus (T2DM) in low- and middle-income countries, like Bangladesh. However, there is no relevant available online published data for this country. We aimed at assessing the 10-year CVD risk among T2DM subjects in selected areas of Bangladesh using the without cholesterol-based joint World Health Organization/International Society of Hypertension (WHO/ISH), Globorisk, and Framingham Risk Score (FRS) risk prediction tools, and also evaluating the concordance among these tools. METHODS AND MATERIALS: In this paper, we extracted a total of 327 subjects (40-60 years aged) from an observational study with 356 subjects, excluding those with diagnosed CVDs. The subjects were selected conveniently from purposively selected respective diabetic hospitals of Pirojpur and Dinajpur districts. We used the required respective variables of WHO/ISH, Globorisk, and FRS tools to predict CVD risks. The risks were categorized as low (<10%), moderate (10-<20%), high (20-<30%) and very high (>/=30%). RESULTS: Subjects at moderate CVD risk were much higher identified by Globorisk (37.0%) and FRS (38.8%) compared to WHO/ISH (15.3%), and the same scenarios have also been observed for high (13.5%, 19.3% and 2.4%, respectively) and very high (5.5%, 17.4% and 1.8%, respectively) risks. There was fair level of concordance between WHO/ISH and Globorisk (PABAK-OS k = 0.37; 95% CI 0.33-0.42; P < 0.001), and Globorisk and FRS (PABAK-OS k = 0.34; 95% CI 0.30-0.39; P < 0.001). And, between WHO/ISH and FRS, it was none to slight level (PABAK-OS k = 0.09, 95% CI 0.04-0.14; P = 0.001). CONCLUSIONS: A significant proportion of the selected study subjects is at moderate to very high risk of developing CVDs predicted especially by Globorisk and FRS compared to WHO/ISH, indicating low concordance. With and without cholesterol-based studies can answer the problem more clearly. CI - (c) 2021 The Author(s). FAU - Mondal, Rajib AU - Mondal R AD - Department of Public Health, Hamdard University Bangladesh (HUB), Gazaria, Munshiganj, Bangladesh. AD - Department of Public Health and Research, Center for Noncommunicable Diseases Prevention Control Rehabilitation & Research (CeNoR), Dhaka, Bangladesh. FAU - Ritu, Rani Baroi AU - Ritu RB AD - Department of Public Health and Research, Center for Noncommunicable Diseases Prevention Control Rehabilitation & Research (CeNoR), Dhaka, Bangladesh. FAU - Banik, Palash Chandra AU - Banik PC AD - Department of Noncommunicable Diseases, Bangladesh University of Health Sciences (BUHS), Dhaka, Bangladesh. LA - eng PT - Journal Article DEP - 20210805 PL - England TA - Heliyon JT - Heliyon JID - 101672560 PMC - PMC8358158 OTO - NOTNLM OT - Bangladesh OT - Cardiovascular risk OT - Concordance OT - Diabetic subjects OT - Without cholesterol-based tools COIS- The authors declare no conflict of interest. EDAT- 2021/08/18 06:00 MHDA- 2021/08/18 06:01 PMCR- 2021/08/05 CRDT- 2021/08/17 07:33 PHST- 2021/01/02 00:00 [received] PHST- 2021/07/22 00:00 [revised] PHST- 2021/08/03 00:00 [accepted] PHST- 2021/08/17 07:33 [entrez] PHST- 2021/08/18 06:00 [pubmed] PHST- 2021/08/18 06:01 [medline] PHST- 2021/08/05 00:00 [pmc-release] AID - S2405-8440(21)01831-4 [pii] AID - e07728 [pii] AID - 10.1016/j.heliyon.2021.e07728 [doi] PST - epublish SO - Heliyon. 2021 Aug 5;7(8):e07728. doi: 10.1016/j.heliyon.2021.e07728. eCollection 2021 Aug.