PMID- 34402030
OWN - NLM
STAT- MEDLINE
DCOM- 20220726
LR  - 20220726
IS  - 1863-4362 (Electronic)
IS  - 0021-1265 (Linking)
VI  - 191
IP  - 4
DP  - 2022 Aug
TI  - The impact of diabetes mellitus on medical complication and mortality rates among 
      inpatients with bullous pemphigoid.
PG  - 1669-1675
LID - 10.1007/s11845-021-02726-9 [doi]
AB  - BACKGROUND: There is currently limited population-based data on the effect of 
      type 2 diabetes mellitus (T2DM) on bullous pemphigoid (BP) inpatients. AIMS: To 
      evaluate the relative comorbidities, medical complications, and mortality rates 
      between BP inpatients with and without T2DM. METHODS: All inpatients with a 
      primary BP diagnosis in the National Inpatient Sample from 2003 to 2012 were 
      queried. BP inpatients with or without T2DM were compared to identify disparities 
      in relative comorbidities and medical complications. Comorbidities were 
      established using the Agency for Healthcare Research and Quality standardized 
      values. Medical complications were classified using ICD-9 codes. RESULTS: Of the 
      1978 BP patients identified, 660 (33.4%) had a concurrent diagnosis of T2DM. 
      These patients had significantly higher rates of concurrent comorbidities, 
      including chronic renal failure, congestive heart failure, iron deficiency 
      anemia, hypertension, obesity, and peripheral vascular disease. On bivariate 
      analysis, T2DM patients also had significantly higher rates of medical 
      complications including acute kidney injury (14.5% vs. 10.1%, p = 0.004) and 
      venous thromboembolism (1.8% vs. 0.5%, p = 0.012). On multivariable-adjusted 
      analysis, the odds of venous thromboembolism (OR = 3.01, p = 0.027) remained 
      increased. Inpatient mortality did not differ between the groups. CONCLUSIONS: 
      Our findings suggest that BP inpatients with T2DM have a greater medical 
      comorbidity and complication burden. However, inpatient mortality was not 
      increased.
CI  - (c) 2021. Royal Academy of Medicine in Ireland.
FAU - Patel, Shreya
AU  - Patel S
AD  - Department of Dermatology, Rutgers New Jersey Medical School, Newark, NJ, USA.
FAU - Ahsanuddin, Salma
AU  - Ahsanuddin S
AD  - Department of Dermatology, Rutgers New Jersey Medical School, Newark, NJ, USA.
FAU - Cadwell, Joshua B
AU  - Cadwell JB
AD  - Department of Dermatology, Rutgers New Jersey Medical School, Newark, NJ, USA.
FAU - Lambert, W Clark
AU  - Lambert WC
AUID- ORCID: 0000-0001-5456-9735
AD  - Department of Dermatology, Rutgers New Jersey Medical School, Newark, NJ, USA. 
      wclambert3129@gmail.com.
AD  - Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey 
      Medical School, Newark, NJ, USA. wclambert3129@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20210816
PL  - Ireland
TA  - Ir J Med Sci
JT  - Irish journal of medical science
JID - 7806864
SB  - IM
MH  - Comorbidity
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Humans
MH  - Inpatients
MH  - *Pemphigoid, Bullous/complications/epidemiology
MH  - Retrospective Studies
MH  - Risk Factors
MH  - *Venous Thromboembolism
OTO - NOTNLM
OT  - Bullous pemphigoid
OT  - Complications
OT  - Diabetes
OT  - Inpatient
OT  - Mortality
OT  - National Inpatient Sample
EDAT- 2021/08/18 06:00
MHDA- 2022/07/27 06:00
CRDT- 2021/08/17 07:41
PHST- 2020/12/12 00:00 [received]
PHST- 2021/07/28 00:00 [accepted]
PHST- 2021/08/18 06:00 [pubmed]
PHST- 2022/07/27 06:00 [medline]
PHST- 2021/08/17 07:41 [entrez]
AID - 10.1007/s11845-021-02726-9 [pii]
AID - 10.1007/s11845-021-02726-9 [doi]
PST - ppublish
SO  - Ir J Med Sci. 2022 Aug;191(4):1669-1675. doi: 10.1007/s11845-021-02726-9. Epub 
      2021 Aug 16.