PMID- 34405588
OWN - NLM
STAT- MEDLINE
DCOM- 20211123
LR  - 20211123
IS  - 2054-1058 (Electronic)
IS  - 2054-1058 (Linking)
VI  - 8
IP  - 6
DP  - 2021 Nov
TI  - Impact of adverse events on patient outcomes in a Japanese intensive care unit: a 
      retrospective observational study.
PG  - 3271-3280
LID - 10.1002/nop2.1040 [doi]
AB  - AIM: We investigated adverse events (AEs) in a Japanese intensive care unit (ICU) 
      and evaluated the impact of cause-specific AEs on mortality and length of stay. 
      DESIGN: A retrospective observational study in the ICU of an academic hospital. 
      METHODS: We reviewed medical records with the Global Trigger Tool. RESULTS: Of 
      the 246 patients, 126 (51%) experienced one or more AEs with an incidence of 201 
      per 1000 patient-days and 115 per 100 admissions. A total of 294 AEs were 
      detected with 119 (42%) adverse drug events, 67 (24%) procedural complications, 
      63 (22%) surgical complications, 26 (9%) nosocomial infections, 5 (2%) 
      therapeutic errors and 4 (1%) diagnostic errors. Adverse event (AE) presence was 
      associated with length of ICU stay (beta = 2.85, 95% confidence interval [CI]: 
      1.09-4.61). Adverse drug events, procedural complications and nosocomial 
      infections were strongly associated with length of ICU stay (beta = 2.38, 95% CI: 
      0.77-3.98; beta = 3.75, 95% CI: 2.03-5.48; beta = 6.52, 95% CI: 4.07-8.97 
      respectively).
CI  - (c) 2021 The Authors. Nursing Open published by John Wiley & Sons Ltd.
FAU - Aikawa, Gen
AU  - Aikawa G
AUID- ORCID: 0000-0002-7404-5442
AD  - Department of Emergency and Critical Care Medicine, Faculty of Medicine, 
      University of Tsukuba, Tsukuba, Japan.
AD  - Intensive Care Unit, University of Tsukuba Hospital, Tsukuba, Japan.
FAU - Ouchi, Akira
AU  - Ouchi A
AUID- ORCID: 0000-0003-4740-0098
AD  - Department of Adult Health Nursing, College of Nursing, Ibaraki Christian 
      University, Hitachi, Japan.
FAU - Sakuramoto, Hideaki
AU  - Sakuramoto H
AUID- ORCID: 0000-0002-2370-2588
AD  - Department of Adult Health Nursing, College of Nursing, Ibaraki Christian 
      University, Hitachi, Japan.
FAU - Ono, Chiemi
AU  - Ono C
AD  - Intensive Care Unit, University of Tsukuba Hospital, Tsukuba, Japan.
FAU - Hatozaki, Chie
AU  - Hatozaki C
AD  - Intensive Care Unit, University of Tsukuba Hospital, Tsukuba, Japan.
FAU - Okamoto, Mayu
AU  - Okamoto M
AD  - Intensive Care Unit, University of Tsukuba Hospital, Tsukuba, Japan.
FAU - Hoshino, Tetsuya
AU  - Hoshino T
AD  - Department of Emergency and Critical Care Medicine, Faculty of Medicine, 
      University of Tsukuba, Tsukuba, Japan.
FAU - Shimojo, Nobutake
AU  - Shimojo N
AD  - Department of Emergency and Critical Care Medicine, Faculty of Medicine, 
      University of Tsukuba, Tsukuba, Japan.
FAU - Inoue, Yoshiaki
AU  - Inoue Y
AD  - Department of Emergency and Critical Care Medicine, Faculty of Medicine, 
      University of Tsukuba, Tsukuba, Japan.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20210817
PL  - United States
TA  - Nurs Open
JT  - Nursing open
JID - 101675107
SB  - IM
MH  - Hospitalization
MH  - Humans
MH  - *Intensive Care Units
MH  - Japan/epidemiology
MH  - *Medical Errors
MH  - Retrospective Studies
PMC - PMC8510737
OTO - NOTNLM
OT  - adverse event
OT  - global trigger tool
OT  - intensive care
OT  - patient safety
COIS- The authors declare that they have no conflicts of interest.
EDAT- 2021/08/19 06:00
MHDA- 2021/11/24 06:00
PMCR- 2021/08/17
CRDT- 2021/08/18 06:55
PHST- 2021/06/10 00:00 [revised]
PHST- 2021/03/14 00:00 [received]
PHST- 2021/08/04 00:00 [accepted]
PHST- 2021/08/19 06:00 [pubmed]
PHST- 2021/11/24 06:00 [medline]
PHST- 2021/08/18 06:55 [entrez]
PHST- 2021/08/17 00:00 [pmc-release]
AID - NOP21040 [pii]
AID - 10.1002/nop2.1040 [doi]
PST - ppublish
SO  - Nurs Open. 2021 Nov;8(6):3271-3280. doi: 10.1002/nop2.1040. Epub 2021 Aug 17.