PMID- 34405789
OWN - NLM
STAT- MEDLINE
DCOM- 20211001
LR  - 20211001
IS  - 1469-7629 (Electronic)
IS  - 0022-0299 (Linking)
VI  - 88
IP  - 3
DP  - 2021 Aug
TI  - Comparison of metabolic, oxidative and inflammatory status of Simmental x 
      Holstein crossbred with parental breeds during the peripartal and early lactation 
      periods.
PG  - 253-260
LID - 10.1017/S0022029921000650 [doi]
AB  - The aim of the research reported in this paper was to evaluate plasma 
      concentrations of energy, oxidative and inflammatory biomarkers of Simmental 
      (sire) x Holstein (dam) crossbred cows, in comparison with the two parental 
      breeds during the peripartal and early lactation periods and to estimate the 
      effects of heterosis for these traits. Thirty-three animals, managed under the 
      same conditions, 8 Simmental (SI), 9 Holstein (HO) and 16 crossbred (CR) cows 
      were enrolled in this study. Glucose, non-esterified fatty acids (NEFA), 
      beta-hydroxybutyrate (BHB), total bilirubin, aspartate aminotransferase (AST), 
      alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatine kinase (CK), 
      total protein, albumin, creatinine and urea were determined in blood sampled at 
      six different time points (30 +/- 3 and 15 +/- 3 d before the expected calving date, 
      at calving and 15, 30 and 60 d after calving). Furthermore, derived reactive 
      oxygen metabolites (d-ROMs), biological antioxidant potential (BAP), 
      interleukin-6 (IL-6), haptoglobin (Hp) and serum amyloid A protein (SAA) were 
      determined to evaluate inflammatory and oxidative status. Results showed that the 
      CR group had significantly lower average values of glucose and NEFA when compared 
      to HO group; signifcantly lower values of urea than SI group and significantly 
      higher values of creatinine than HO. Furthermore, CR cows showed the lowest 
      average value of d-ROMs with respect to SI and HO parental breeds. Finally, the 
      average value of haptoglobin was significantly lower in CR and HO groups, when 
      compared to SI group. As for the heterosis we found the highest (positive) 
      percentage for CK (98%) and BAP (47%) and the lowest (negative) percentage for 
      OSi (-75%) and d-ROMs (-39%). A negative percentage was also found for the 
      glucose (-11%) and NEFA (-20%) toward the Simmental parental breed. Our results 
      suggest a different response among the three genetic groups during the peripartal 
      and early lactation periods. In particular, CR and SI cows seem more adaptable 
      regarding energy metabolism and oxidative status. Heterosis led to a positive 
      effect on those parameters in Simmental (sire) x Holstein (dam) crossbred cows F1 
      population (50% Simmental and 50% Holstein).
FAU - De Matteis, Giovanna
AU  - De Matteis G
AD  - Council for Agricultural Research and Economics, CREA Research Centre for Animal 
      Production and Aquaculture, Via Salaria 31, 00015Monterotondo, RM, Italy.
FAU - Scata, Maria Carmela
AU  - Scata MC
AD  - Council for Agricultural Research and Economics, CREA Research Centre for Animal 
      Production and Aquaculture, Via Salaria 31, 00015Monterotondo, RM, Italy.
FAU - Catillo, Gennaro
AU  - Catillo G
AD  - Council for Agricultural Research and Economics, CREA Research Centre for Animal 
      Production and Aquaculture, Via Salaria 31, 00015Monterotondo, RM, Italy.
FAU - Grandoni, Francesco
AU  - Grandoni F
AD  - Council for Agricultural Research and Economics, CREA Research Centre for Animal 
      Production and Aquaculture, Via Salaria 31, 00015Monterotondo, RM, Italy.
FAU - Rossi, Emanuela
AU  - Rossi E
AD  - Council for Agricultural Research and Economics, CREA Research Centre for Animal 
      Production and Aquaculture, Via Salaria 31, 00015Monterotondo, RM, Italy.
FAU - Meo Zilio, David
AU  - Meo Zilio D
AD  - Council for Agricultural Research and Economics, CREA Research Centre for Animal 
      Production and Aquaculture, Via Salaria 31, 00015Monterotondo, RM, Italy.
FAU - Crisa, Alessandra
AU  - Crisa A
AD  - Council for Agricultural Research and Economics, CREA Research Centre for Animal 
      Production and Aquaculture, Via Salaria 31, 00015Monterotondo, RM, Italy.
FAU - Lopreiato, Vincenzo
AU  - Lopreiato V
AD  - Department of Animal Sciences, Food and Nutrition, Faculty of Agriculture, Food 
      and Environmental Science, Universita Cattolica del Sacro Cuore, 29122Piacenza, 
      Italy.
FAU - Trevisi, Erminio
AU  - Trevisi E
AD  - Department of Animal Sciences, Food and Nutrition, Faculty of Agriculture, Food 
      and Environmental Science, Universita Cattolica del Sacro Cuore, 29122Piacenza, 
      Italy.
FAU - Barile, Vittoria Lucia
AU  - Barile VL
AD  - Council for Agricultural Research and Economics, CREA Research Centre for Animal 
      Production and Aquaculture, Via Salaria 31, 00015Monterotondo, RM, Italy.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20210818
PL  - England
TA  - J Dairy Res
JT  - The Journal of dairy research
JID - 2985125R
RN  - 0 (Biomarkers)
SB  - IM
MH  - Animals
MH  - Biomarkers/blood
MH  - Cattle/*genetics
MH  - Cattle Diseases/blood
MH  - Energy Metabolism/*genetics/physiology
MH  - Female
MH  - Hybrid Vigor/physiology
MH  - *Hybridization, Genetic
MH  - Inflammation/blood/veterinary
MH  - Lactation/blood/*genetics
MH  - Oxidative Stress/*genetics/physiology
MH  - Peripartum Period/blood/*genetics
MH  - Species Specificity
OTO - NOTNLM
OT  - Crossbred
OT  - inflammatory response
OT  - metabolic profile
OT  - oxidative stress
OT  - peripartum
EDAT- 2021/08/19 06:00
MHDA- 2021/10/02 06:00
CRDT- 2021/08/18 08:47
PHST- 2021/08/19 06:00 [pubmed]
PHST- 2021/10/02 06:00 [medline]
PHST- 2021/08/18 08:47 [entrez]
AID - S0022029921000650 [pii]
AID - 10.1017/S0022029921000650 [doi]
PST - ppublish
SO  - J Dairy Res. 2021 Aug;88(3):253-260. doi: 10.1017/S0022029921000650. Epub 2021 
      Aug 18.