PMID- 34406298
OWN - NLM
STAT- MEDLINE
DCOM- 20210820
LR  - 20220531
IS  - 1806-9282 (Electronic)
IS  - 0104-4230 (Linking)
VI  - 67Suppl 1
IP  - Suppl 1
DP  - 2021
TI  - Evaluation of cardiac parameters between survivors and nonsurvivors of COVID-19 
      patients.
PG  - 80-85
LID - S0104-42302021000200080 [pii]
LID - 10.1590/1806-9282.67.Suppl1.20200848 [doi]
AB  - OBJECTIVE: The present study compares the cardiac parameters of the survivor and 
      nonsurvivor patients with COVID-19 infection. METHODS: This study was conducted 
      in 379 patients diagnosed with COVID-19 disease. Information of 21 nonsurvivor 
      and 358 survivor patients with COVID-19 was obtained from the hospital 
      information management system and analyzed retrospectively. Relationship between 
      cardiac parameters in patients categorized into the mortal and immortal groups 
      was investigated. RESULTS: Of the total 379 patients involved in this study, 155 
      (40.9%) were females and 224 (59.1%) were males. No statistically significant 
      difference in mortality was found between females and males (p=0.249). The total 
      median age was 70, the median age in the nonsurvivor group was 74 (35-89), and it 
      was 69.5 (18-96) in the survivor group (p=0.249). The median values of 
      high-sensitivity troponin (hs-Tn), creatine kinase MB form, and especially 
      myoglobin in the survivor and nonsurvivor groups were 25/64.9 (p=0.028), 18/23 
      (p=0.02), and 105.5/322.4 (p<0.001), and the difference was statistically 
      significant. Comparing mortality, while there was 1 (0.7%) nonsurvivor out of 134 
      patients in the service unit, there were 20 (8.2%) nonsurvivors out of 245 
      patients in the intensive care unit. This difference was statistically 
      significant (p=0.003). The cutoff value of myoglobin, which may pose a risk of 
      mortality, was found to be 191.4 microg/L, while it was 45.7 ng/l for hs-Tn and 60.1 
      U/L for creatine kinase MB. CONCLUSIONS: Advanced age and increased levels of 
      high-sensitivity troponin, creatine kinase MB, and myoglobin were found to be 
      associated with mortality.
FAU - Ozdin, Mehmet
AU  - Ozdin M
AUID- ORCID: 0000-0003-3077-7171
AD  - Sakarya University Education and Research Hospital, Medical Biochemistry 
      Laboratory - Sakarya, Turkey.
FAU - Yazar, Hayrullah
AU  - Yazar H
AUID- ORCID: 0000-0001-9447-6322
AD  - Sakarya University Education and Research Hospital, Medical Biochemistry 
      Laboratory - Sakarya, Turkey.
AD  - Sakarya University, Faculty of Medicine, Department of Medical Biochemistry - 
      Sakarya, Turkey.
FAU - Yaylaci, Selcuk
AU  - Yaylaci S
AUID- ORCID: 0000-0002-6768-7973
AD  - Sakarya University, Faculty of Medicine, Department of Internal Medicine - 
      Sakarya, Turkey.
FAU - Koroglu, Mehmet
AU  - Koroglu M
AUID- ORCID: 0000-0002-5918-4479
AD  - Sakarya University, Faculty of Medicine, Department of Medical Microbiology - 
      Sakarya, Turkey.
FAU - Genc, Ahmed Cihad
AU  - Genc AC
AUID- ORCID: 0000-0002-7725-707X
AD  - Sakarya University, Faculty of Medicine, Department of Internal Medicine - 
      Sakarya, Turkey.
FAU - Kocayigit, Ibrahim
AU  - Kocayigit I
AUID- ORCID: 0000-0001-8295-9837
AD  - Sakarya University, Faculty of Medicine, Department of Cardiology - Sakarya, 
      Turkey.
FAU - Genc, Ahmed Bilal
AU  - Genc AB
AUID- ORCID: 0000-0002-1607-6355
AD  - Sakarya University, Faculty of Medicine, Department of Internal Medicine - 
      Sakarya, Turkey.
FAU - Yildirim, Ilhan
AU  - Yildirim I
AUID- ORCID: 0000-0003-0600-7249
AD  - Sakarya University, Faculty of Medicine, Department of Internal Medicine - 
      Sakarya, Turkey.
FAU - Kocayigit, Havva
AU  - Kocayigit H
AUID- ORCID: 0000-0002-8719-7031
AD  - Sakarya University, Faculty of Medicine, Department of Anesthesiology and 
      Reanimation - Sakarya, Turkey.
FAU - Karabay, Oguz
AU  - Karabay O
AUID- ORCID: 0000-0003-1514-1685
AD  - Sakarya University, Faculty of Medicine, Department of Infectious Disease and 
      Clinical Microbiology - Sakarya, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20210813
PL  - Brazil
TA  - Rev Assoc Med Bras (1992)
JT  - Revista da Associacao Medica Brasileira (1992)
JID - 9308586
RN  - 0 (Biomarkers)
RN  - EC 2.7.3.2 (Creatine Kinase)
SB  - IM
EIN - Rev Assoc Med Bras (1992). 2021 Jul;67(7):1075. PMID: 34817529
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Biomarkers
MH  - *COVID-19
MH  - Creatine Kinase
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - SARS-CoV-2
MH  - Survivors
EDAT- 2021/08/19 06:00
MHDA- 2021/08/21 06:00
CRDT- 2021/08/18 12:24
PHST- 2020/11/26 00:00 [received]
PHST- 2020/11/29 00:00 [accepted]
PHST- 2021/08/18 12:24 [entrez]
PHST- 2021/08/19 06:00 [pubmed]
PHST- 2021/08/21 06:00 [medline]
AID - S0104-42302021000200080 [pii]
AID - 10.1590/1806-9282.67.Suppl1.20200848 [doi]
PST - epublish
SO  - Rev Assoc Med Bras (1992). 2021 Aug 13;67Suppl 1(Suppl 1):80-85. doi: 
      10.1590/1806-9282.67.Suppl1.20200848. eCollection 2021.