PMID- 34408947
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210820
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 13
IP  - 7
DP  - 2021 Jul
TI  - The Pattern of Valvular Heart Diseases in India During Pregnancy and Its 
      Outcomes.
PG  - e16394
LID - 10.7759/cureus.16394 [doi]
LID - e16394
AB  - INTRODUCTION: The incidence of rheumatic heart disease is very high in India. The 
      data on the pattern of valvular heart diseases during pregnancy and its outcomes 
      is very scarce. Again, the data in the Indian scenario, the differences in 
      outcomes between different grades of valvular heart diseases and its impact on 
      pregnancy outcomes is very less. We planned to study the different patterns of 
      valvular heart diseases during pregnancy and their outcomes with respect to 
      cardiac complication and perinatal outcomes. MATERIALS AND METHODS: It was a 
      hospital-based prospective observational study. We recruited 71 patients after 
      taking written informed consent. All patients were with term gestation and 
      valvular heart diseases. We did 2D echocardiography to analyze the valve lesion 
      and assess the valve lesion with its maternal and perinatal outcomes. RESULTS: 
      The mean age of participants in the study was 27 + 5.2 years. A total of 54 
      patients (76.1%) were less than 30 years and 17 (23.9%) were more than 30 years 
      of age. Six patients (8.5%) presented with New York Heart Association (NYHA) 
      class I, 39 patients (54.9%) presented with NYHA class II, 25 patients (35.2%) 
      presented with NYHA class III and one patient (1.4%) presented with NYHA class 
      IV. The most common etiology of valvular heart diseases was found to be rheumatic 
      in 62 patients (87.3%). The most common valve involved was the mitral valve 
      (69%). New-onset atrial fibrillation (AF) was reported in 26.8% patients and 
      pulmonary edema developed in 15.5% patients. Live birth was observed in 66 
      patients (93%) compared to stillbirth reported in five patients (7%). CONCLUSION: 
      No significant difference in maternal and perinatal outcomes between moderate and 
      severe grades of different valvular heart diseases.
CI  - Copyright (c) 2021, Kumari et al.
FAU - Kumari, Anupama
AU  - Kumari A
AD  - Obstetrics and Gynaecology, Patna Medical College, Patna, IND.
FAU - Kumar, Kamlesh
AU  - Kumar K
AD  - Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research, 
      Puducherry, IND.
FAU - Kumar Sinha, Abhay
AU  - Kumar Sinha A
AD  - Internal Medicine, Patna Medical College, Patna, IND.
LA  - eng
PT  - Journal Article
DEP - 20210714
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC8363483
OTO - NOTNLM
OT  - aortic stenosis
OT  - india
OT  - maternal outcomes
OT  - mitral stenosis
OT  - perinatal outcomes
OT  - pregnancy
OT  - rheumatic
OT  - valvular heart disease
COIS- The authors have declared that no competing interests exist.
EDAT- 2021/08/20 06:00
MHDA- 2021/08/20 06:01
PMCR- 2021/07/14
CRDT- 2021/08/19 06:43
PHST- 2021/07/14 00:00 [accepted]
PHST- 2021/08/19 06:43 [entrez]
PHST- 2021/08/20 06:00 [pubmed]
PHST- 2021/08/20 06:01 [medline]
PHST- 2021/07/14 00:00 [pmc-release]
AID - 10.7759/cureus.16394 [doi]
PST - epublish
SO  - Cureus. 2021 Jul 14;13(7):e16394. doi: 10.7759/cureus.16394. eCollection 2021 
      Jul.