PMID- 34410189
OWN - NLM
STAT- MEDLINE
DCOM- 20211124
LR  - 20211124
IS  - 2325-8179 (Electronic)
IS  - 2325-8160 (Linking)
VI  - 52
IP  - 8
DP  - 2021 Aug
TI  - Retinopathy of Prematurity Screening Examination and Changes in Vital Signs.
PG  - 458-463
LID - 10.3928/23258160-20210727-10 [doi]
AB  - BACKGROUND AND OBJECTIVE: Dilation and examination during retinopathy of 
      prematurity (ROP) screening can cause systemic complications and even 
      life-threatening adverse events (AEs). The main objective of this study is to 
      assess the prevalence and significance of AEs and changes in vital signs during 
      ROP screenings, and to correlate birth weight, gestational age, and length of 
      exam as possible predictors of these changes. PATIENTS AND METHODS: This is a 
      prospective, observational study that includes 1,360 screening exams from 680 
      premature infants in two neonatal intensive care units. Systolic blood pressure, 
      diastolic blood pressure, heart rate, respiratory rate, and oxygen saturation 
      were monitored from the time that dilating drops were administered until 4 hours 
      after the examination was completed. Any clinical deterioration or complication 
      was documented. RESULTS: Of 1,360 infant screening exams, 153 (11%) screening 
      exams resulted in at least one change in vital sign that alerted the monitor. 
      There was one serious AE requiring bag valve mask resuscitation 30 minutes after 
      dilating drops were placed. Gestational age, birth weight, and length of ROP exam 
      were not significant predictors of AEs. There were statistically significant 
      changes when comparing pre- and post-vital signs following dilation and 
      funduscopy exam. CONCLUSIONS: Although ROP screening exams are essential for 
      at-risk neonates, mydriatic drops and retinal exams can result in changes to 
      vital signs and AEs. It is important to closely monitor neonates during these 
      examinations. [Ophthalmic Surg Lasers Imaging Retina. 2021;52:458-463.].
FAU - Lahoti, Sejal
AU  - Lahoti S
FAU - Jones, Richard
AU  - Jones R
FAU - Beck, Kinley D
AU  - Beck KD
FAU - Padidam, Sneha
AU  - Padidam S
FAU - Apple, Daniel
AU  - Apple D
FAU - Lin, Xihui
AU  - Lin X
FAU - Quiram, Polly
AU  - Quiram P
FAU - Young, Ryan C
AU  - Young RC
FAU - Desireddi, Jennifer
AU  - Desireddi J
FAU - Harper, C Armitage 3rd
AU  - Harper CA 3rd
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20210801
PL  - United States
TA  - Ophthalmic Surg Lasers Imaging Retina
JT  - Ophthalmic surgery, lasers & imaging retina
JID - 101599215
SB  - IM
MH  - Gestational Age
MH  - Humans
MH  - Infant
MH  - Infant, Low Birth Weight
MH  - Infant, Newborn
MH  - Infant, Premature
MH  - Neonatal Screening
MH  - Prospective Studies
MH  - *Retinopathy of Prematurity/diagnosis/epidemiology
MH  - Risk Factors
MH  - Vital Signs
EDAT- 2021/08/20 06:00
MHDA- 2021/11/25 06:00
CRDT- 2021/08/19 12:14
PHST- 2021/08/19 12:14 [entrez]
PHST- 2021/08/20 06:00 [pubmed]
PHST- 2021/11/25 06:00 [medline]
AID - 10.3928/23258160-20210727-10 [doi]
PST - ppublish
SO  - Ophthalmic Surg Lasers Imaging Retina. 2021 Aug;52(8):458-463. doi: 
      10.3928/23258160-20210727-10. Epub 2021 Aug 1.