PMID- 34416721 OWN - NLM STAT- MEDLINE DCOM- 20220413 LR - 20230617 IS - 1547-5646 (Electronic) IS - 1547-5646 (Linking) VI - 35 IP - 6 DP - 2021 Aug 20 TI - National adverse event profile after lumbar spine surgery for lumbar degenerative disorders and comparison of complication rates between hospitals: a CSORN registry study. PG - 698-703 LID - 10.3171/2021.2.SPINE202150 [doi] AB - OBJECTIVE: Previous works investigating rates of adverse events (AEs) in spine surgery have been retrospective, with data collection from administrative databases, and often from single centers. To date, there have been no prospective reports capturing AEs in spine surgery on a national level, with comparison among centers. METHODS: The Spine Adverse Events Severity system was used to define the incidence and severity of AEs after spine surgery by using data from the Canadian Spine Outcomes and Research Network (CSORN) prospective registry. Patient data were collected prospectively and during hospital admission for those undergoing elective spine surgery for degenerative conditions. The Spine Adverse Events Severity system defined minor and major AEs as grades 1-2 and 3-6, respectively. RESULTS: There were 3533 patients enrolled in this cohort. There were 85 (2.4%) individual patients with at least one major AE and 680 (19.2%) individual patients with at least one minor AE. There were 25 individual patients with 28 major intraoperative AEs and 260 patients with 275 minor intraoperative AEs. Postoperatively there were 61 patients with a total of 80 major AEs. Of the 487 patients with minor AEs postoperatively there were 698 total AEs. The average enrollment was 321 patients (range 47-1237 patients) per site. The rate of major AEs was consistent among sites (mean 2.9% +/- 2.4%, range 0%-9.1%). However, the rate of minor AEs varied widely among sites-from 7.9% to 42.5%, with a mean of 18.8% +/- 9.7%. The rate of minor AEs varied depending on how they were reported, with surgeon reporting associated with the lowest rates (p < 0.01). CONCLUSIONS: The rate of major AEs after lumbar spine surgery is consistent among different sites but the rate of minor AEs appears to vary substantially. The method by which AEs are reported impacts the rate of minor AEs. These data have implications for the detection and reporting of AEs and the design of strategies aimed at mitigating complications. FAU - Ayling, Oliver G S AU - Ayling OGS AD - 1Department of Surgery, Vancouver General Hospital/University of British Columbia, Vancouver, British Columbia. FAU - Charest-Morin, Raphaele AU - Charest-Morin R AD - 1Department of Surgery, Vancouver General Hospital/University of British Columbia, Vancouver, British Columbia. FAU - Eagles, Matthew E AU - Eagles ME AD - 4Department of Surgery, University of Calgary, Alberta. FAU - Ailon, Tamir AU - Ailon T AD - 1Department of Surgery, Vancouver General Hospital/University of British Columbia, Vancouver, British Columbia. FAU - Street, John T AU - Street JT AD - 1Department of Surgery, Vancouver General Hospital/University of British Columbia, Vancouver, British Columbia. FAU - Dea, Nicolas AU - Dea N AD - 1Department of Surgery, Vancouver General Hospital/University of British Columbia, Vancouver, British Columbia. FAU - McIntosh, Greg AU - McIntosh G AD - 2Canadian Spine Society, Markdale, Ontario. FAU - Christie, Sean D AU - Christie SD AD - 10Department of Surgery, Dalhousie University, Halifax, Nova Scotia; and. FAU - Abraham, Edward AU - Abraham E AD - 3Department of Surgery, Canada East Spine Centre, Saint John, New Brunswick. FAU - Jacobs, W Bradley AU - Jacobs WB AD - 4Department of Surgery, University of Calgary, Alberta. FAU - Bailey, Christopher S AU - Bailey CS AD - 7Department of Surgery, University of Western Ontario, London, Ontario. FAU - Johnson, Michael G AU - Johnson MG AD - 5Departments of Orthopedics and Neurosurgery, University of Manitoba, Winnipeg, Manitoba. FAU - Attabib, Najmedden AU - Attabib N AD - 10Department of Surgery, Dalhousie University, Halifax, Nova Scotia; and. FAU - Jarzem, Peter AU - Jarzem P AD - 11Department of Surgery, McGill University, Montreal, Quebec, Canada. FAU - Weber, Michael AU - Weber M AD - 11Department of Surgery, McGill University, Montreal, Quebec, Canada. FAU - Paquet, Jerome AU - Paquet J AD - 6Department of Surgery, Laval University, Quebec City, Quebec. FAU - Finkelstein, Joel AU - Finkelstein J AD - 9Department of Surgery, University of Toronto, Ontario. FAU - Stratton, Alexandra AU - Stratton A AD - 8Department of Surgery, University of Ottawa, Ontario. FAU - Hall, Hamilton AU - Hall H AD - 9Department of Surgery, University of Toronto, Ontario. FAU - Manson, Neil AU - Manson N AD - 3Department of Surgery, Canada East Spine Centre, Saint John, New Brunswick. FAU - Rampersaud, Y Raja AU - Rampersaud YR AD - 9Department of Surgery, University of Toronto, Ontario. FAU - Thomas, Kenneth AU - Thomas K AD - 4Department of Surgery, University of Calgary, Alberta. FAU - Fisher, Charles G AU - Fisher CG AD - 1Department of Surgery, Vancouver General Hospital/University of British Columbia, Vancouver, British Columbia. LA - eng PT - Journal Article DEP - 20210820 PL - United States TA - J Neurosurg Spine JT - Journal of neurosurgery. Spine JID - 101223545 SB - IM MH - Canada/epidemiology MH - *Hospitals MH - Humans MH - Lumbar Vertebrae/surgery MH - *Postoperative Complications/epidemiology MH - Registries MH - Retrospective Studies OTO - NOTNLM OT - CSORN OT - Canadian Spine Outcomes and Research Network OT - adverse events OT - complication OT - degenerative OT - lumbar spine OT - surgery EDAT- 2021/08/21 06:00 MHDA- 2022/04/14 06:00 CRDT- 2021/08/20 20:30 PHST- 2020/12/18 00:00 [received] PHST- 2021/02/04 00:00 [accepted] PHST- 2021/08/21 06:00 [pubmed] PHST- 2022/04/14 06:00 [medline] PHST- 2021/08/20 20:30 [entrez] AID - 10.3171/2021.2.SPINE202150 [doi] PST - epublish SO - J Neurosurg Spine. 2021 Aug 20;35(6):698-703. doi: 10.3171/2021.2.SPINE202150.