PMID- 34420136
OWN - NLM
STAT- MEDLINE
DCOM- 20220221
LR  - 20220221
IS  - 1559-0720 (Electronic)
IS  - 0163-4984 (Linking)
VI  - 200
IP  - 4
DP  - 2022 Apr
TI  - Health Risk Assessment of Occupational Exposure to Hexavalent Chromium in Iranian 
      Workplaces: a Meta-analysis Study.
PG  - 1551-1560
LID - 10.1007/s12011-021-02789-w [doi]
AB  - Occupational exposure to hexavalent chromium (Cr(+6)) has reported in different 
      industries. The Cr(6+) has the carcinogenic and non-carcinogenic effects. The aim 
      of this study was to provide a meta-analysis and health risk assessment of 
      occupational exposure to Cr(6+) in Iranian workplaces. Databases including 
      Scopus, Web of Sciences (WOS), and Scientific Information Database (SID), as a 
      national database, were searched from 2000 to February 2021. The related studies 
      to occupational exposure to Cr(6+) were selected by Preferred Reporting Items for 
      Systematic Reviews and Meta-Analyses (PRISMA) protocol. Lung cancer and 
      non-cancer risk (nasal mucosal irritation, atrophy, and perforation) of Cr(6+) 
      were estimated by Environmental Protection Agency (EPA) method, based on the 
      Monte Carlo simulation (MCS). Also, the results of spirometry and biomonitoring 
      of previous studies were reviewed. We found 14 articles based on inclusion 
      criteria. Pooled concentration of Cr(6+) was estimated 0.037 +/- 0.002 mg/m(3) 
      which was higher than the recommended exposure limit by the ACGIH 
      (0.002 mg/m(3)). The mean lung cancer risk was estimated to be 5.49E-2, which was 
      considerable risk. In the Cr(6+)-exposed workers, all parameters of pulmonary 
      function had decreased. The level of Cr(6+) in urinary and blood samples was 
      higher than threshold limit. Results indicated that exposure to Cr(6+) and its 
      health risk were more than recommended exposure limit. The results of present 
      study could be helpful for health policy maker to control exposure to Cr(6+) in 
      workplaces.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Nasirzadeh, Nafiseh
AU  - Nasirzadeh N
AUID- ORCID: 0000-0003-0378-9927
AD  - Department of Occupational Health Engineering, School of Public Health, Tehran 
      University of Medical Science, Tehran, Iran.
FAU - Mohammadian, Yousef
AU  - Mohammadian Y
AUID- ORCID: 0000-0002-5545-3619
AD  - Department of Occupational Health Engineering, Faculty of Health, Tabriz 
      University of Medical Science, 5165665931, Tabriz, Iran. 
      Mohammadiany@tbzmed.ac.ir.
FAU - Dehgan, Golnoush
AU  - Dehgan G
AD  - Department of Occupational Health Engineering, Faculty of Health, Tabriz 
      University of Medical Science, 5165665931, Tabriz, Iran.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
DEP - 20210822
PL  - United States
TA  - Biol Trace Elem Res
JT  - Biological trace element research
JID - 7911509
RN  - 0R0008Q3JB (Chromium)
RN  - 18540-29-9 (chromium hexavalent ion)
SB  - IM
MH  - Chromium/analysis/toxicity
MH  - Humans
MH  - Iran/epidemiology
MH  - *Occupational Exposure/analysis
MH  - Risk Assessment
MH  - *Workplace
OTO - NOTNLM
OT  - Biomonitoring
OT  - Chromium
OT  - Lung cancer risk
OT  - Non-cancer risk
OT  - Occupational exposure
OT  - Systematic review
EDAT- 2021/08/23 06:00
MHDA- 2022/02/22 06:00
CRDT- 2021/08/22 21:08
PHST- 2021/04/06 00:00 [received]
PHST- 2021/06/09 00:00 [accepted]
PHST- 2021/08/23 06:00 [pubmed]
PHST- 2022/02/22 06:00 [medline]
PHST- 2021/08/22 21:08 [entrez]
AID - 10.1007/s12011-021-02789-w [pii]
AID - 10.1007/s12011-021-02789-w [doi]
PST - ppublish
SO  - Biol Trace Elem Res. 2022 Apr;200(4):1551-1560. doi: 10.1007/s12011-021-02789-w. 
      Epub 2021 Aug 22.