PMID- 34422433
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210824
IS  - 2090-8865 (Print)
IS  - 2090-8873 (Electronic)
IS  - 2090-8873 (Linking)
VI  - 2021
DP  - 2021
TI  - Rapid Determination of 21 Chinese Domestically Registered Pesticides in Ginseng 
      Using Cleanup Based on Zirconium-Oxide-Modified Silica and Ultrahigh-Performance 
      Liquid Chromatography-Tandem Mass Spectrometry.
PG  - 5516563
LID - 10.1155/2021/5516563 [doi]
LID - 5516563
AB  - In this study, an analytical method was developed for the rapid determination of 
      21 pesticides used in ginseng cultivation. All pesticides covered by this method 
      have been registered by 2020 in China for use on ginseng. The extracts were 
      cleaned up using zirconium-oxide-modified silica (Z-Sep) and primary secondary 
      amine (PSA). The combination of Z-Sep and PSA provided good recovery for all 
      analytes and the cleanest matrix background out of a number of PSA-based sorbent 
      combinations, as indicated by high-performance liquid chromatography (HPLC) and 
      gas chromatography (GC). Instrumental analysis was completed in 5 min using the 
      ultrahigh-performance liquid chromatography-tandem mass spectrometry 
      (UHPLC-MS/MS). The linearity (r > 0.99) for all analytes was satisfactory over 
      the calibration range of 0.002-0.1 mug mL(-1). Intraday recoveries (n = 5) at 
      ginseng-spiked levels of 0.02, 0.05, 0.1, and 1 mg kg(-1) ranged between 72% and 
      119%, with the corresponding relative standard deviations (RSDs), were less than 
      19%, while the interday recoveries (n = 15) ranged between 77% and 103%, and RSDs 
      were less than 22%. Limits of quantitation (LOQs) ranged between 0.02 and 
      0.05 mg kg(-1) for all 21 pesticides. This is a seminal study using Z-Sep for the 
      efficient cleanup of ginseng samples, and it could present a practical method for 
      future monitoring of pesticide residues in ginseng produced in China.
CI  - Copyright (c) 2021 Zhongbei Zhang et al.
FAU - Zhang, Zhongbei
AU  - Zhang Z
AUID- ORCID: 0000-0003-4164-7639
AD  - College of Plant Protection, Jilin Agricultural University, Changchun 130118, 
      Jilin, China.
FAU - Lu, Zhou
AU  - Lu Z
AUID- ORCID: 0000-0003-4248-2581
AD  - College of Plant Protection, Jilin Agricultural University, Changchun 130118, 
      Jilin, China.
AD  - Laboratory of Quality & Safety Risk Assessment for Ginseng and Antler Products, 
      Jilin Agricultural University, Changchun 130118, Jilin, China.
FAU - Fang, Nan
AU  - Fang N
AUID- ORCID: 0000-0002-6998-9852
AD  - College of Plant Protection, Jilin Agricultural University, Changchun 130118, 
      Jilin, China.
FAU - Hou, Zhiguang
AU  - Hou Z
AUID- ORCID: 0000-0003-4350-2871
AD  - College of Plant Protection, Jilin Agricultural University, Changchun 130118, 
      Jilin, China.
FAU - Ren, Weiming
AU  - Ren W
AUID- ORCID: 0000-0001-7824-6404
AD  - College of Plant Protection, Jilin Agricultural University, Changchun 130118, 
      Jilin, China.
FAU - Li, Yueru
AU  - Li Y
AUID- ORCID: 0000-0001-5579-2373
AD  - Laboratory of Quality & Safety Risk Assessment for Ginseng and Antler Products, 
      Jilin Agricultural University, Changchun 130118, Jilin, China.
FAU - Lu, Zhongbin
AU  - Lu Z
AUID- ORCID: 0000-0003-3796-0956
AD  - College of Plant Protection, Jilin Agricultural University, Changchun 130118, 
      Jilin, China.
LA  - eng
PT  - Journal Article
DEP - 20210813
PL  - Egypt
TA  - J Anal Methods Chem
JT  - Journal of analytical methods in chemistry
JID - 101575377
PMC - PMC8378960
COIS- The authors declare that they have no known competing financial interests or 
      personal relationships that could have appeared to influence the work reported in 
      this paper.
EDAT- 2021/08/24 06:00
MHDA- 2021/08/24 06:01
PMCR- 2021/08/13
CRDT- 2021/08/23 06:33
PHST- 2021/02/20 00:00 [received]
PHST- 2021/06/24 00:00 [revised]
PHST- 2021/07/23 00:00 [accepted]
PHST- 2021/08/23 06:33 [entrez]
PHST- 2021/08/24 06:00 [pubmed]
PHST- 2021/08/24 06:01 [medline]
PHST- 2021/08/13 00:00 [pmc-release]
AID - 10.1155/2021/5516563 [doi]
PST - epublish
SO  - J Anal Methods Chem. 2021 Aug 13;2021:5516563. doi: 10.1155/2021/5516563. 
      eCollection 2021.