PMID- 34423080
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220426
IS  - 2333-9748 (Print)
IS  - 2333-9748 (Electronic)
IS  - 2333-9748 (Linking)
VI  - 7
IP  - 3
DP  - 2021 May
TI  - Hand Nicotine and Cotinine In Children Exposed to Cigars: A Pilot Study.
PG  - 170-176
LID - 10.18001/trs.7.3.2 [doi]
AB  - OBJECTIVES: Past research has not examined secondhand and thirdhand smoke (THS) 
      exposure in children of cigar smokers. We examined hand nicotine and cotinine 
      levels in children of cigar smokers to explore the contribution of cigar smoke to 
      tobacco smoke exposure (TSE). METHODS: Participants were children (N = 24; mean 
      (SD) age = 6.5 (3.6) years) whose parents smoked cigars only or poly-used cigars 
      and/or cigarettes. Primary outcomes were hand nicotine and urinary cotinine 
      levels. RESULTS: All children had detectable hand nicotine (range: 
      7.6-312.5ng/wipe) and cotinine (range: 0.3-100.3ng/ml). Positive correlations 
      were found between hand nicotine and cotinine (r = 0.693, p = .001), hand 
      nicotine and parents who also smoked cigarettes (r = 0.407, p = .048), and hand 
      nicotine and number of smokers around the child (r = 0.436, p = .03). Hand 
      nicotine (r = -0.464, p = .02), but not cotinine (r = -0.266, p = .26), was 
      negatively correlated with child age. Multiple regression results indicated a 
      positive association between hand nicotine and cotinine (p = .002; semi-partial 
      r(2) = 0.415), irrespective of child age. CONCLUSIONS: The significant 
      association of hand nicotine with urinary cotinine suggests that THS pollution 
      should be assessed in evaluating children's overall TSE to cigars and other 
      tobacco products, and hand nicotine may be a proxy for overall TSE. Younger 
      children may have increased THS pollutant uptake.
FAU - Mahabee-Gittens, E Melinda
AU  - Mahabee-Gittens EM
AD  - E. Melinda Mahabee-Gittens, Professor, Division of Emergency Medicine, Cincinnati 
      Children's Hospital Medical Center, University of Cincinnati College of Medicine, 
      Cincinnati, OH, United States. Georg E. Matt, Professor, Department of 
      Psychology, San Diego State University, San Diego, CA, United States. Roman J. 
      Jandarov, Assistant Professor, Department of Environmental Health, Division of 
      Biostatistics and Bioinformatics, University of Cincinnati College of Medicine, 
      Cincinnati, OH, United States. Ashley L. Merianos, Associate Professor, School of 
      Human Services, University of Cincinnati, Cincinnati, OH, United States.
FAU - Matt, Georg E
AU  - Matt GE
AD  - E. Melinda Mahabee-Gittens, Professor, Division of Emergency Medicine, Cincinnati 
      Children's Hospital Medical Center, University of Cincinnati College of Medicine, 
      Cincinnati, OH, United States. Georg E. Matt, Professor, Department of 
      Psychology, San Diego State University, San Diego, CA, United States. Roman J. 
      Jandarov, Assistant Professor, Department of Environmental Health, Division of 
      Biostatistics and Bioinformatics, University of Cincinnati College of Medicine, 
      Cincinnati, OH, United States. Ashley L. Merianos, Associate Professor, School of 
      Human Services, University of Cincinnati, Cincinnati, OH, United States.
FAU - Jandarov, Roman J
AU  - Jandarov RJ
AD  - E. Melinda Mahabee-Gittens, Professor, Division of Emergency Medicine, Cincinnati 
      Children's Hospital Medical Center, University of Cincinnati College of Medicine, 
      Cincinnati, OH, United States. Georg E. Matt, Professor, Department of 
      Psychology, San Diego State University, San Diego, CA, United States. Roman J. 
      Jandarov, Assistant Professor, Department of Environmental Health, Division of 
      Biostatistics and Bioinformatics, University of Cincinnati College of Medicine, 
      Cincinnati, OH, United States. Ashley L. Merianos, Associate Professor, School of 
      Human Services, University of Cincinnati, Cincinnati, OH, United States.
FAU - Merianos, Ashley L
AU  - Merianos AL
AD  - E. Melinda Mahabee-Gittens, Professor, Division of Emergency Medicine, Cincinnati 
      Children's Hospital Medical Center, University of Cincinnati College of Medicine, 
      Cincinnati, OH, United States. Georg E. Matt, Professor, Department of 
      Psychology, San Diego State University, San Diego, CA, United States. Roman J. 
      Jandarov, Assistant Professor, Department of Environmental Health, Division of 
      Biostatistics and Bioinformatics, University of Cincinnati College of Medicine, 
      Cincinnati, OH, United States. Ashley L. Merianos, Associate Professor, School of 
      Human Services, University of Cincinnati, Cincinnati, OH, United States.
LA  - eng
GR  - K01 DA044313/DA/NIDA NIH HHS/United States
GR  - R01 ES027815/ES/NIEHS NIH HHS/United States
GR  - R01 ES030743/ES/NIEHS NIH HHS/United States
GR  - R21 ES032161/ES/NIEHS NIH HHS/United States
PT  - Journal Article
PL  - United States
TA  - Tob Regul Sci
JT  - Tobacco regulatory science
JID - 101655763
PMC - PMC8378668
MID - NIHMS1707708
OTO - NOTNLM
OT  - adolescent/youth
OT  - cigar/cigarillo
OT  - secondhand smoke
OT  - thirdhand smoke
OT  - tobacco exposure
OT  - toxicant
COIS- Conflict of Interest Disclosure Statement The authors have no conflicts of 
      interest to disclose.
EDAT- 2021/08/24 06:00
MHDA- 2021/08/24 06:01
PMCR- 2021/08/20
CRDT- 2021/08/23 06:39
PHST- 2021/08/23 06:39 [entrez]
PHST- 2021/08/24 06:00 [pubmed]
PHST- 2021/08/24 06:01 [medline]
PHST- 2021/08/20 00:00 [pmc-release]
AID - 10.18001/trs.7.3.2 [doi]
PST - ppublish
SO  - Tob Regul Sci. 2021 May;7(3):170-176. doi: 10.18001/trs.7.3.2.