PMID- 34439591
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210830
IS  - 2076-3425 (Print)
IS  - 2076-3425 (Electronic)
IS  - 2076-3425 (Linking)
VI  - 11
IP  - 8
DP  - 2021 Jul 23
TI  - Impact of a Carbohydrate Mouth Rinse on Corticomotor Excitability after Mental 
      Fatigue in Healthy College-Aged Subjects.
LID - 10.3390/brainsci11080972 [doi]
LID - 972
AB  - Mental Fatigue (MF) has been associated with reduced physical performance but the 
      mechanisms underlying this result are unclear. A reduction in excitability of the 
      corticomotor system is a way mental fatigue could negatively impact physical 
      performance. Carbohydrate (CHO) mouth rinse (MR) has been shown to increase 
      corticomotor excitability. PURPOSE: The purpose of this study was to determine if 
      CHO MR impacts corticomotor excitability after MF. METHODS: Fifteen subjects 
      (nine females, six males; age = 23 +/- 1 years; height = 171 +/- 2 cm; body mass = 69 
      +/- 3 kg; BMI = 23.8 +/- 0.7) completed two sessions under different MR conditions 
      (Placebo (PLAC), 6.4% glucose (CHO)) separated by at least 48 h and applied in a 
      double-blinded randomized fashion. Motor-evoked potential (MEP) of the left first 
      dorsal interosseous (FDI) was determined by transcranial magnetic stimulation 
      (TMS) before and after MF. Perceived MF was recorded before and after the MF task 
      using a 100 mm visual analog scale (VAS). RESULTS: MF was greater following PLAC 
      (+30.4 +/- 4.0 mm) than CHO (+19.4 +/- 3.9 mm) (p = 0.005). MEP was reduced more 
      following PLAC (-16.6 +/- 4.4%) than CHO (-3.7 +/- 4.7%) (p < 0.001). CONCLUSIONS: 
      CHO MR was successful at attenuating the reduction in corticomotor excitability 
      after MF. Carbohydrate mouth rinse may be a valuable tool at combating the 
      negative consequences of mental fatigue.
FAU - Bailey, Stephen P
AU  - Bailey SP
AD  - Department of Physical Therapy Education, Elon University, Elon, NC 27244, USA.
FAU - Harris, G Keith
AU  - Harris GK
AUID- ORCID: 0000-0002-3424-1836
AD  - Department of Food, Bioprocessing, and Nutrition Sciences, NC State University, 
      Raleigh, NC 27695, USA.
FAU - Lewis, Kaitlin
AU  - Lewis K
AD  - Department of Physical Therapy Education, Elon University, Elon, NC 27244, USA.
FAU - Llewellyn, Tracy A
AU  - Llewellyn TA
AD  - Department of Physical Therapy Education, Elon University, Elon, NC 27244, USA.
FAU - Watkins, Ruth
AU  - Watkins R
AD  - Department of Food, Bioprocessing, and Nutrition Sciences, NC State University, 
      Raleigh, NC 27695, USA.
FAU - Weaver, Mark A
AU  - Weaver MA
AD  - Department of Mathematics & Statistics, Elon University, Elon, NC 27244, USA.
FAU - Roelands, Bart
AU  - Roelands B
AUID- ORCID: 0000-0002-2808-044X
AD  - Human Physiology and Sports Physiotherapy Research Group, Vrije Universiteit 
      Brussel, 1050 Brussels, Belgium.
AD  - Sport and Exercise Science, School of Psychology and Life Sciences, Canterbury 
      Christ Church University, Canterbury Campus, Canterbury, Kent CT1 1QU, UK.
FAU - Van Cutsem, Jeroen
AU  - Van Cutsem J
AD  - Human Physiology and Sports Physiotherapy Research Group, Vrije Universiteit 
      Brussel, 1050 Brussels, Belgium.
AD  - VIPER Research Unit, Royal Military Academy, 1000 Brussels, Belgium.
FAU - Folger, Stephen F
AU  - Folger SF
AD  - Department of Physical Therapy Education, Elon University, Elon, NC 27244, USA.
LA  - eng
PT  - Journal Article
DEP - 20210723
PL  - Switzerland
TA  - Brain Sci
JT  - Brain sciences
JID - 101598646
PMC - PMC8391817
OTO - NOTNLM
OT  - TMS
OT  - carbohydrate
OT  - mental fatigue
COIS- The authors declare no conflict of interest.
EDAT- 2021/08/28 06:00
MHDA- 2021/08/28 06:01
PMCR- 2021/07/23
CRDT- 2021/08/27 01:04
PHST- 2021/06/11 00:00 [received]
PHST- 2021/07/15 00:00 [revised]
PHST- 2021/07/20 00:00 [accepted]
PHST- 2021/08/27 01:04 [entrez]
PHST- 2021/08/28 06:00 [pubmed]
PHST- 2021/08/28 06:01 [medline]
PHST- 2021/07/23 00:00 [pmc-release]
AID - brainsci11080972 [pii]
AID - brainsci-11-00972 [pii]
AID - 10.3390/brainsci11080972 [doi]
PST - epublish
SO  - Brain Sci. 2021 Jul 23;11(8):972. doi: 10.3390/brainsci11080972.