PMID- 34441768 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210831 IS - 2077-0383 (Print) IS - 2077-0383 (Electronic) IS - 2077-0383 (Linking) VI - 10 IP - 16 DP - 2021 Aug 6 TI - Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective Study. LID - 10.3390/jcm10163472 [doi] LID - 3472 AB - BACKGROUND: The aim of the study is to investigate whether the circadian IOP rhythm can be influenced by combined cataract surgery with high frequency deep sclerotomy (HFDS) and whether intraocular pressure (IOP) can be significantly reduced by HFDS. METHODS: In our study 10 patients were included, in whom 24 h IOP monitoring was installed before and after HFDS/cataract surgery using a Triggerfish. HFDS is a minimally invasive glaucoma surgery (MIGS). RESULTS: After performed HFDS combined with cataract surgery, the IOP was reduced from 27.7 +/- 2.11 mmHg to 14.4 +/- 2.59 mmHg, which is highly significant (p < 0.001). The contact lens sensor (CLS) cosinor analysis pre- and postoperatively showed that the circadian rhythm is not influenced by the surgery, i.e., the circadian IOP rhythm did not show significant differences before and after surgery. CONCLUSIONS: HFDS combined with cataract surgery is a potent surgical method that can significantly reduce the IOP. However, the circadian rhythm cannot be changed by the surgery. The acrophase remained during the night in all patients. FAU - Pajic, Bojan AU - Pajic B AUID- ORCID: 0000-0003-1987-6232 AD - Eye Clinic Orasis, Swiss Eye Research Foundation, 5734 Reinach AG, Switzerland. AD - Department of Physics, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovica 4, 21000 Novi Sad, Serbia. AD - Department of Clinical Neurosciences, Division of Ophthalmology, Geneva University Hospitals, 1205 Geneva, Switzerland. AD - Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland. AD - Faculty of Medicine of the Military Medical Academy, University of Defense, 11000 Belgrade, Serbia. FAU - Resan, Mirko AU - Resan M AD - Faculty of Medicine of the Military Medical Academy, University of Defense, 11000 Belgrade, Serbia. FAU - Pajic-Eggspuehler, Brigitte AU - Pajic-Eggspuehler B AD - Eye Clinic Orasis, Swiss Eye Research Foundation, 5734 Reinach AG, Switzerland. FAU - Massa, Horace AU - Massa H AUID- ORCID: 0000-0001-5025-3856 AD - Department of Clinical Neurosciences, Division of Ophthalmology, Geneva University Hospitals, 1205 Geneva, Switzerland. FAU - Cvejic, Zeljka AU - Cvejic Z AUID- ORCID: 0000-0002-8218-4899 AD - Department of Physics, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovica 4, 21000 Novi Sad, Serbia. LA - eng PT - Journal Article DEP - 20210806 PL - Switzerland TA - J Clin Med JT - Journal of clinical medicine JID - 101606588 PMC - PMC8396965 OTO - NOTNLM OT - IOP pattern OT - Triggerfish OT - high frequency deep sclerotomy (HFDS) OT - minimal invasive glaucoma surgery (MIGS) COIS- The authors declare no conflict of interest. EDAT- 2021/08/28 06:00 MHDA- 2021/08/28 06:01 PMCR- 2021/08/06 CRDT- 2021/08/27 01:10 PHST- 2021/07/11 00:00 [received] PHST- 2021/07/30 00:00 [revised] PHST- 2021/08/04 00:00 [accepted] PHST- 2021/08/27 01:10 [entrez] PHST- 2021/08/28 06:00 [pubmed] PHST- 2021/08/28 06:01 [medline] PHST- 2021/08/06 00:00 [pmc-release] AID - jcm10163472 [pii] AID - jcm-10-03472 [pii] AID - 10.3390/jcm10163472 [doi] PST - epublish SO - J Clin Med. 2021 Aug 6;10(16):3472. doi: 10.3390/jcm10163472.