PMID- 34441952
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210831
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 10
IP  - 16
DP  - 2021 Aug 18
TI  - Early Gender Differences in Pain and Functional Recovery Following Thoracolumbar 
      Spinal Arthrodesis.
LID - 10.3390/jcm10163654 [doi]
LID - 3654
AB  - BACKGROUND: To analyze gender differences regarding the recovery experience 
      (pain, function, complications) after spinal arthrodesis surgery. METHODS: 
      Pre-operative and post-operative gender-based differences in patient-reported 
      outcomes for open posterior spinal arthrodesis at 6 weeks, 3 months, 6 months, 
      and 1 year were studied, including age, comorbidities, body mass index (BMI), 
      diagnosis, number of vertebrae fused, type of surgery, primary vs. revision 
      surgery, and complications. Statistical analysis included the use of Student's 
      t-test, Chi square, linear regression, Mann-Whitney U test, and Spearman's rho. 
      RESULTS: Primary or revision posterior arthrodesis was performed on 1931 
      consecutive adults (1219 females, 712 males) for deformity and degenerative 
      pathologies. At surgery, females were older than males (61.7 years vs. 59.7 
      years, p < 0.01), had slightly more comorbidities (1.75 vs. 1.5, p < 0.01), and 
      were more likely to undergo deformity correction (38% vs. 22%, p < 0.01). Females 
      described more pre-op pain (female VAS = 6.54 vs. male VAS = 6.41, p < 0.01) and 
      lower pre-op function (female ODI = 49.73 vs. male ODI = 46.52, p < 0.01). By 3 
      months post-op, there was no significant gender difference in VAS or ODI scores. 
      Similar pain and function scores between males and females continued through 6 
      months and 12 months. CONCLUSION: Although females have more pain and dysfunction 
      before undergoing spinal surgery, the differences in these values do not reach 
      the Minimum Clinically Important Difference (MCID). Post-operatively, there is no 
      difference in pain and function scores among males and females at 3, 6, and 12 
      months.
FAU - Gulbrandsen, Matthew T
AU  - Gulbrandsen MT
AD  - Department of Orthopedic Surgery, Loma Linda University, Loma Linda, CA 92354, 
      USA.
FAU - Lara, Nina
AU  - Lara N
AD  - Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ 85054, USA.
FAU - Beauchamp, James A
AU  - Beauchamp JA
AD  - Department of Biomedical Engineering, Northwestern University, Evanston, IL 
      60208, USA.
FAU - Chung, Andrew
AU  - Chung A
AUID- ORCID: 0000-0003-3942-9595
AD  - Sonoran Spine Center, Tempe, AZ 85281, USA.
FAU - Chang, Michael
AU  - Chang M
AD  - Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ 85054, USA.
AD  - Sonoran Spine Center, Tempe, AZ 85281, USA.
FAU - Crandall, Dennis
AU  - Crandall D
AD  - Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ 85054, USA.
AD  - Sonoran Spine Center, Tempe, AZ 85281, USA.
LA  - eng
PT  - Journal Article
DEP - 20210818
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC8397048
OTO - NOTNLM
OT  - deformity
OT  - gender differences
OT  - spinal fusion
OT  - spine
OT  - spine arthrodesis
COIS- The authors declare no conflict of interest.
EDAT- 2021/08/28 06:00
MHDA- 2021/08/28 06:01
PMCR- 2021/08/18
CRDT- 2021/08/27 01:11
PHST- 2021/07/14 00:00 [received]
PHST- 2021/08/13 00:00 [accepted]
PHST- 2021/08/27 01:11 [entrez]
PHST- 2021/08/28 06:00 [pubmed]
PHST- 2021/08/28 06:01 [medline]
PHST- 2021/08/18 00:00 [pmc-release]
AID - jcm10163654 [pii]
AID - jcm-10-03654 [pii]
AID - 10.3390/jcm10163654 [doi]
PST - epublish
SO  - J Clin Med. 2021 Aug 18;10(16):3654. doi: 10.3390/jcm10163654.