PMID- 34443858
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210831
IS  - 2079-4991 (Print)
IS  - 2079-4991 (Electronic)
IS  - 2079-4991 (Linking)
VI  - 11
IP  - 8
DP  - 2021 Aug 9
TI  - Improvement of PMMA Dental Matrix Performance by Addition of Titanium Dioxide 
      Nanoparticles and Clay Nanotubes.
LID - 10.3390/nano11082027 [doi]
LID - 2027
AB  - Over the last decades, several materials have been proposed for the fabrication 
      of dental and mandibular prosthetic implants. Today, the 
      poly(methyl-methacrylate) (PMMA) resin is the most spread material, due to its 
      ease of processing, low cost, aesthetic properties, low weight, biocompatibility, 
      and biostability in the oral cavity. However, the porous surface (which favors 
      the adhesion of microorganisms) and the weak mechanical properties (which lead to 
      wear or fracture) are the major concerns. The inclusion of engineered 
      nanomaterials in the acrylic matrix could improve the performances of PMMA. In 
      this study, we added two different kind of nanomaterials, namely titanium dioxide 
      nanoparticles (TiO(2)NPs) and halloysite clay nanotubes (HNTs) at two 
      concentrations (1% and 3% w/w) in PMMA. Then, we assessed the effect of 
      nanomaterials inclusion by the evaluation of specific physical parameters: 
      Young's modulus, roughness, and wettability. In addition, we investigated the 
      potential beneficial effects regarding the Candida albicans (C. albicans) 
      colonization reduction, the most common yeast responsible of several infections 
      in oral cavity. Our experimental results showed an improvement of PMMA 
      performance, following the addition of TiO(2)NPs and HNTs, in a dose dependent 
      manner. In particular, the presence of TiO(2)NPs in the methacrylate matrix 
      induced a greater increase in PMMA stiffness respect to HNTs addition. On the 
      other hand, HNTs reduced the rate of C. albicans colonization more significantly 
      than TiO(2)NPs. The results obtained are of great interest for the improvement of 
      PMMA physico-chemical properties, in view of its possible application in clinical 
      dentistry.
FAU - Cascione, Mariafrancesca
AU  - Cascione M
AUID- ORCID: 0000-0001-9849-5301
AD  - Department of Mathematics and Physics "Ennio De Giorgi", University of Salento, 
      73100 Lecce, Italy.
FAU - De Matteis, Valeria
AU  - De Matteis V
AUID- ORCID: 0000-0003-2204-8817
AD  - Department of Mathematics and Physics "Ennio De Giorgi", University of Salento, 
      73100 Lecce, Italy.
FAU - Pellegrino, Paolo
AU  - Pellegrino P
AUID- ORCID: 0000-0001-6018-3548
AD  - Department of Mathematics and Physics "Ennio De Giorgi", University of Salento, 
      73100 Lecce, Italy.
FAU - Albanese, Giovanni
AU  - Albanese G
AD  - U.O.C. of Plastic Surgery and Burns Center, Department of Oral Hygiene Clinic, 
      Hospital "A. Perrino", 72100 Brindisi, Italy.
AD  - Dental School, Interdisciplinary Department of Medicine, University of Bari "Aldo 
      Moro", 70124 Bari, Italy.
FAU - De Giorgi, Maria Luisa
AU  - De Giorgi ML
AUID- ORCID: 0000-0002-3774-6477
AD  - Department of Mathematics and Physics "Ennio De Giorgi", University of Salento, 
      73100 Lecce, Italy.
FAU - Paladini, Fabio
AU  - Paladini F
AD  - Department of Mathematics and Physics "Ennio De Giorgi", University of Salento, 
      73100 Lecce, Italy.
FAU - Corsalini, Massimo
AU  - Corsalini M
AUID- ORCID: 0000-0002-0521-1363
AD  - Dental School, Interdisciplinary Department of Medicine, University of Bari "Aldo 
      Moro", 70124 Bari, Italy.
FAU - Rinaldi, Rosaria
AU  - Rinaldi R
AUID- ORCID: 0000-0003-2798-9341
AD  - Department of Mathematics and Physics "Ennio De Giorgi", University of Salento, 
      73100 Lecce, Italy.
LA  - eng
PT  - Journal Article
DEP - 20210809
PL  - Switzerland
TA  - Nanomaterials (Basel)
JT  - Nanomaterials (Basel, Switzerland)
JID - 101610216
PMC - PMC8402145
OTO - NOTNLM
OT  - Candida albicans
OT  - HNTs
OT  - TiO2NPs
OT  - mechanical analysis
OT  - oral prostheses
OT  - poly(methyl methacrylate)
OT  - wettability
COIS- The authors declare no conflict of interest.
EDAT- 2021/08/28 06:00
MHDA- 2021/08/28 06:01
PMCR- 2021/08/09
CRDT- 2021/08/27 01:17
PHST- 2021/05/25 00:00 [received]
PHST- 2021/07/30 00:00 [revised]
PHST- 2021/08/04 00:00 [accepted]
PHST- 2021/08/27 01:17 [entrez]
PHST- 2021/08/28 06:00 [pubmed]
PHST- 2021/08/28 06:01 [medline]
PHST- 2021/08/09 00:00 [pmc-release]
AID - nano11082027 [pii]
AID - nanomaterials-11-02027 [pii]
AID - 10.3390/nano11082027 [doi]
PST - epublish
SO  - Nanomaterials (Basel). 2021 Aug 9;11(8):2027. doi: 10.3390/nano11082027.