PMID- 34448760
OWN - NLM
STAT- MEDLINE
DCOM- 20211230
LR  - 20211230
IS  - 1524-4725 (Electronic)
IS  - 1076-0512 (Linking)
VI  - 47
IP  - 9
DP  - 2021 Sep 1
TI  - Safety Profile for Microneedling: A Systematic Review.
PG  - 1249-1254
LID - 10.1097/01.DSS.0000790428.70373.f6 [doi]
AB  - BACKGROUND: Microneedling is a minimally invasive procedure that stimulates 
      collagen and elastin proliferation. It is used in the treatment of various skin 
      pathologies, that is, scarring, photodamage, and hair loss; however, its safety 
      profile has yet to be comprehensively reviewed. OBJECTIVE: This review will 
      discuss the reported side effects of microneedling in the current literature and 
      delineate factors that increase the risk of complications. MATERIALS AND METHODS: 
      A literature search in August 2019 was conducted using the PubMed database to 
      identify studies reporting adverse events (AEs) after microneedling therapy. 
      RESULTS: Eighty-five articles were included in this systematic review. The most 
      common reported AEs are transient procedural events that are expected 
      postprocedure lasting up to 7 days, such as transient erythema/edema and pain, 
      postinflammatory hyperpigmentation (PIH), dry skin/exfoliation, lymphadenopathy, 
      and irritant contact dermatitis. Persistent serious adverse effects included PIH, 
      tram-track scarring, and granulomatous reactions. Factors that increase the risk 
      of events are active infections, darker skin, and metal allergies. CONCLUSION: 
      Microneedling is a relatively safe therapy. Most reported AEs are minimal, 
      resolving quickly and spontaneously. Caution should be taken in patients with 
      active infection, darker skin types, metal allergies, and when used in 
      conjunction with products not approved for intradermal use.
CI  - Copyright (c) 2021 by the American Society for Dermatologic Surgery, Inc. Published 
      by Wolters Kluwer Health, Inc. All rights reserved.
FAU - Chu, Sherman
AU  - Chu S
AD  - Department of Dermatology, University of California-Irvine, Irvine, California.
AD  - Department of Dermatology, Case Western Reserve University, Cleveland, Ohio.
AD  - Department of Dermatology, University Hospitals Cleveland Medical Center, 
      Cleveland, Ohio.
AD  - University Hospitals Regional Hospitals, Richmond Heights, Ohio.
FAU - Foulad, Delila P
AU  - Foulad DP
AD  - Department of Dermatology, University of California-Irvine, Irvine, California.
FAU - Atanaskova Mesinkovska, Natasha
AU  - Atanaskova Mesinkovska N
AD  - Department of Dermatology, University of California-Irvine, Irvine, California.
LA  - eng
PT  - Journal Article
PT  - Systematic Review
PL  - United States
TA  - Dermatol Surg
JT  - Dermatologic surgery : official publication for American Society for Dermatologic 
      Surgery [et al.]
JID - 9504371
SB  - IM
MH  - Cosmetic Techniques/*adverse effects/*instrumentation
MH  - Humans
MH  - *Needles
MH  - Skin Diseases/*therapy
EDAT- 2021/08/28 06:00
MHDA- 2021/12/31 06:00
CRDT- 2021/08/27 12:21
PHST- 2021/08/27 12:21 [entrez]
PHST- 2021/08/28 06:00 [pubmed]
PHST- 2021/12/31 06:00 [medline]
AID - 00042728-202109000-00013 [pii]
AID - 10.1097/01.DSS.0000790428.70373.f6 [doi]
PST - ppublish
SO  - Dermatol Surg. 2021 Sep 1;47(9):1249-1254. doi: 
      10.1097/01.DSS.0000790428.70373.f6.