PMID- 34453013 OWN - NLM STAT- MEDLINE DCOM- 20220217 LR - 20220225 IS - 1543-2742 (Electronic) IS - 1526-484X (Linking) VI - 31 IP - 6 DP - 2021 Nov 1 TI - Carbohydrate and Protein Co-Ingestion Postexercise Does Not Improve Next-Day Performance in Trained Cyclists. PG - 466-474 LID - ijsnem.2021-0069 [pii] LID - 10.1123/ijsnem.2021-0069 [doi] AB - Supplementing postexercise carbohydrate (CHO) intake with protein has been suggested to enhance recovery from endurance exercise. The aim of this study was to investigate whether adding protein to the recovery drink can improve 24-hr recovery when CHO intake is suboptimal. In a double-blind crossover design, 12 trained men performed three 2-day trials consisting of constant-load exercise to reduce glycogen on Day 1, followed by ingestion of a CHO drink (1.2 g.kg-1.2 hr-1) either without or with added whey protein concentrate (CHO + PRO) or whey protein hydrolysate (CHO + PROH) (0.3 g.kg-1.2 hr-1). Arterialized blood glucose and insulin responses were analyzed for 2 hr postingestion. Time-trial performance was measured the next day after another bout of glycogen-reducing exercise. The 30-min time-trial performance did not differ between the three trials (M +/- SD, 401 +/- 75, 411 +/- 80, 404 +/- 58 kJ in CHO, CHO + PRO, and CHO + PROH, respectively, p = .83). No significant differences were found in glucose disposal (area under the curve [AUC]) between the postexercise conditions (364 +/- 107, 341 +/- 76, and 330 +/- 147, mmol.L-1.2 hr-1, respectively). Insulin AUC was lower in CHO (18.1 +/- 7.7 nmol.L-1.2 hr-1) compared with CHO + PRO and CHO + PROH (24.6 +/- 12.4 vs. 24.5 +/- 10.6, p = .036 and .015). No difference in insulin AUC was found between CHO + PRO and CHO + PROH. Despite a higher acute insulin response, adding protein to a CHO-based recovery drink after a prolonged, high-intensity exercise bout did not change next-day exercise capacity when overall 24-hr macronutrient and caloric intake was controlled. FAU - Kontro, Hilkka AU - Kontro H AUID- ORCID: 0000-0001-6999-3096 AD - Food for Health Ireland. AD - University of Limerick. AD - University of Calgary. FAU - Kozior, Marta AU - Kozior M AUID- ORCID: 0000-0003-0945-7560 AD - Food for Health Ireland. AD - University of Limerick. FAU - Whelehan, Grainne AU - Whelehan G AUID- ORCID: 0000-0003-1391-4349 AD - Food for Health Ireland. AD - University of Limerick. FAU - Amigo-Benavent, Miryam AU - Amigo-Benavent M AUID- ORCID: 0000-0002-5376-9708 AD - Food for Health Ireland. AD - University of Limerick. FAU - Norton, Catherine AU - Norton C AUID- ORCID: 0000-0001-8973-6759 AD - Food for Health Ireland. AD - University of Limerick. FAU - Carson, Brian P AU - Carson BP AUID- ORCID: 0000-0001-8350-1481 AD - Food for Health Ireland. AD - University of Limerick. FAU - Jakeman, Phil AU - Jakeman P AUID- ORCID: 0000-0002-1199-080X AD - Food for Health Ireland. AD - University of Limerick. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20210827 PL - United States TA - Int J Sport Nutr Exerc Metab JT - International journal of sport nutrition and exercise metabolism JID - 100939812 RN - 0 (Blood Glucose) RN - 0 (Dietary Carbohydrates) RN - 0 (Insulin) RN - 9005-79-2 (Glycogen) SB - IM MH - Blood Glucose MH - *Dietary Carbohydrates MH - Double-Blind Method MH - Eating MH - Exercise MH - Glycogen MH - Humans MH - Insulin MH - Male MH - *Muscle, Skeletal MH - Physical Endurance OTO - NOTNLM OT - endurance OT - glycogen OT - recovery EDAT- 2021/08/29 06:00 MHDA- 2022/02/19 06:00 CRDT- 2021/08/28 05:32 PHST- 2021/03/11 00:00 [received] PHST- 2021/06/24 00:00 [revised] PHST- 2021/06/28 00:00 [accepted] PHST- 2021/08/29 06:00 [pubmed] PHST- 2022/02/19 06:00 [medline] PHST- 2021/08/28 05:32 [entrez] AID - ijsnem.2021-0069 [pii] AID - 10.1123/ijsnem.2021-0069 [doi] PST - ppublish SO - Int J Sport Nutr Exerc Metab. 2021 Nov 1;31(6):466-474. doi: 10.1123/ijsnem.2021-0069. Epub 2021 Aug 27.