PMID- 34453579
OWN - NLM
STAT- MEDLINE
DCOM- 20220418
LR  - 20220531
IS  - 1437-160X (Electronic)
IS  - 0172-8172 (Linking)
VI  - 42
IP  - 4
DP  - 2022 Apr
TI  - Impact of obesity on quality of life, psychological status, and disease activity 
      in psoriatic arthritis: a multi‑center study.
PG  - 659-668
LID - 10.1007/s00296-021-04971-8 [doi]
AB  - This article aims to evaluate the possible effect of obesity on quality of life, 
      psychological status, and other clinical variables in Psoriatic arthritis (PsA). 
      PsA patients have been recruited by the Turkish League Against Rheumatism-Network 
      from various centers in Turkey in this cross-sectional study. Patients with a 
      body mass index (BMI) >/= of 30 kg/m(2) were considered obese. Differences among 
      patients with regard to obesity status were assessed with health-related quality 
      of life measures (PsA Quality of Life Questionnaire [PsAQoL]), psychological 
      status (Hospital Anxiety and Depression Scale [HADS]), and disease activity 
      parameters (the Disease Activity index for PSoriatic Arthritis [DAPSA], Disease 
      Activity Score 28-C-reactive protein [DAS28-CRP], Bath Ankylosing Spondylitis 
      Disease Activity Index [BASDAI], Psoriasis Area and Severity Index [PASI]), 
      physical functions (Ankylosing Spondylitis Functional Index [BASFI], Health 
      Assessment Questionnaire [HAQ], and Health Assessment Questionnaire for the 
      spondyloarthropathies [HAQ-S]). Pain was assessed using visual analog scale of 
      pain (VAS-P), and fatigue was evaluated using visual analog scale of fatigue 
      (VAS-F) and Functional Assessment of Chronic Illness Therapy (FACIT). A total of 
      1033 patients with PsA, 650 (62.9%) non-obese and 383 (37.1%) obese were included 
      in the study. The PsAQoL, HADS-Anxiety, HADS-Depression, DAPSA, DAS28-CRP, 
      BASDAI, BASFI, HAQ and HAQ-S scores of the obese group were higher than the 
      non-obese group (p < 0.05). VAS-P and PASI scores were similar between group of 
      patients with and without obesity. Obese patients had higher median scores of 
      VAS-F and FACIT than non-obese patients (p < 0.05). Linear regression analysis 
      showed that BMI affects the quality of life, depression, and disease activity. 
      Consequently, obesity has significant associations with higher disease activity, 
      lower QoL, risk of anxiety, depression, and fatigue. Therefore, obesity should 
      also be taken into account in the management of PsA patients.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Gok, Kevser
AU  - Gok K
AUID- ORCID: 0000-0001-8639-751X
AD  - Rheumatology Clinic, Ankara City Hospital, Ankara, Turkey. 
      kevserorhangok@gmail.com.
FAU - Nas, Kemal
AU  - Nas K
AD  - Division of Rheumatology and Immunology, Department of Physical Medicine and 
      Rehabilitation, Sakarya University School of Medicine, Sakarya, Turkey.
FAU - Tekeoglu, Ibrahim
AU  - Tekeoglu I
AUID- ORCID: 0000-0003-3395-7178
AD  - Division of Rheumatology and Immunology, Department of Physical Medicine and 
      Rehabilitation, Sakarya University School of Medicine, Sakarya, Turkey.
FAU - Sunar, Ismihan
AU  - Sunar I
AUID- ORCID: 0000-0002-4435-5677
AD  - Rheumatology Clinic, Aydin State Hospital, Aydin, Turkey.
FAU - Keskin, Yasar
AU  - Keskin Y
AUID- ORCID: 0000-0003-4457-5917
AD  - Department of Physical Medicine and Rehabilitation, Bezmialem Vakif University, 
      Istanbul, Turkey.
FAU - Kilic, Erkan
AU  - Kilic E
AUID- ORCID: 0000-0003-4355-4356
AD  - Rheumatology Clinic, Kanuni Training and Research Hospital, Trabzon, Turkey.
FAU - Sargin, Betul
AU  - Sargin B
AUID- ORCID: 0000-0002-9463-8413
AD  - Division of Rheumatology, Department of Physical Medicine and Rehabilitation, 
      Adnan Menderes University School of Medicine, Aydin, Turkey.
FAU - Acer Kasman, Sevtap
AU  - Acer Kasman S
AUID- ORCID: 0000-0002-4805-0555
AD  - Division of Rheumatology, Department of Physical Medicine and Rehabilitation, 
      Marmara University School of Medicine, Istanbul, Turkey.
FAU - Alkan, Hakan
AU  - Alkan H
AUID- ORCID: 0000-0001-8461-9131
AD  - Department of Physical Medicine and Rehabilitation, Pamukkale University School 
      of Medicine, Denizli, Turkey.
FAU - Sahin, Nilay
AU  - Sahin N
AUID- ORCID: 0000-0001-6062-6935
AD  - Department of Physical Medicine and Rehabilitation, Balikesir University School 
      of Medicine, Balikesir, Turkey.
FAU - Cengiz, Gizem
AU  - Cengiz G
AUID- ORCID: 0000-0002-8143-3048
AD  - Division of Rheumatology, Department of Physical Medicine and Rehabilitation, 
      Erciyes University School of Medicine, Kayseri, Turkey.
FAU - Cuzdan, Nihan
AU  - Cuzdan N
AUID- ORCID: 0000-0001-7238-657X
AD  - Rheumatology Clinic, Balikesir Ataturk City Hospital, Balikesir, Turkey.
FAU - Albayrak Gezer, Ilknur
AU  - Albayrak Gezer I
AUID- ORCID: 0000-0002-8980-1837
AD  - Department of Physical Medicine and Rehabilitation, Selcuk University School of 
      Medicine, Konya, Turkey.
FAU - Keskin, Dilek
AU  - Keskin D
AUID- ORCID: 0000-0001-5300-6391
AD  - Department of Physical Medicine and Rehabilitation, Kirikkale University School 
      of Medicine, Kirikkale, Turkey.
FAU - Mulkoglu, Cevriye
AU  - Mulkoglu C
AUID- ORCID: 0000-0001-9113-3885
AD  - Department of Physical Medicine and Rehabilitation, Ankara Training and Research 
      Hospital, Ankara, Turkey.
FAU - Resorlu, Hatice
AU  - Resorlu H
AUID- ORCID: 0000-0001-9889-1064
AD  - Department of Physical Medicine and Rehabilitation, Canakkale Onsekiz Mart 
      University School of Medicine, Canakkale, Turkey.
FAU - Bal, Ajda
AU  - Bal A
AUID- ORCID: 0000-0002-3910-2851
AD  - Department of Physical Medicine and Rehabilitation, University of Health Sciences 
      Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
FAU - Duruoz, Mehmet Tuncay
AU  - Duruoz MT
AUID- ORCID: 0000-0003-3584-2788
AD  - Division of Rheumatology, Department of Physical Medicine and Rehabilitation, 
      Marmara University School of Medicine, Istanbul, Turkey.
FAU - Kucukakkas, Okan
AU  - Kucukakkas O
AUID- ORCID: 0000-0001-6971-4229
AD  - Department of Physical Medicine and Rehabilitation, Bezmialem Vakif University, 
      Istanbul, Turkey.
FAU - Yurdakul, Ozan Volkan
AU  - Yurdakul OV
AUID- ORCID: 0000-0003-4567-8133
AD  - Department of Physical Medicine and Rehabilitation, Bezmialem Vakif University, 
      Istanbul, Turkey.
FAU - Alkan Melikoglu, Meltem
AU  - Alkan Melikoglu M
AUID- ORCID: 0000-0001-7519-9470
AD  - Division of Rheumatology, Department of Physical Medicine and Rehabilitation, 
      Ataturk University School of Medicine, Erzurum, Turkey.
FAU - Aydin, Yildiray
AU  - Aydin Y
AUID- ORCID: 0000-0003-4299-5627
AD  - Department of Physical Medicine and Rehabilitation, Tekirdag Kapakli State 
      Hospital, Tekirdag, Turkey.
FAU - Ayhan, Fikriye Figen
AU  - Ayhan FF
AUID- ORCID: 0000-0001-6906-991X
AD  - Department of Physical Medicine and Rehabilitation, Atilim University Medical 
      School, Ankara, Turkey.
FAU - Bodur, Hatice
AU  - Bodur H
AUID- ORCID: 0000-0003-3008-7007
AD  - Department of Physical Medicine and Rehabilitation, Yildirim Beyazit University 
      School of Medicine, Ankara, Turkey.
FAU - Calis, Mustafa
AU  - Calis M
AUID- ORCID: 0000-0002-1184-0772
AD  - Division of Rheumatology, Department of Physical Medicine and Rehabilitation, 
      Erciyes University School of Medicine, Kayseri, Turkey.
FAU - Capkin, Erhan
AU  - Capkin E
AUID- ORCID: 0000-0003-2728-5934
AD  - Department of Physical Medicine and Rehabilitation, Karadeniz Technical 
      University School of Medicine, Trabzon, Turkey.
FAU - Devrimsel, Gul
AU  - Devrimsel G
AUID- ORCID: 0000-0001-9775-6426
AD  - Department of Physical Medicine and Rehabilitation, Recep Tayyip Erdogan 
      University School of Medicine, Rize, Turkey.
FAU - Ecesoy, Hilal
AU  - Ecesoy H
AUID- ORCID: 0000-0001-9274-168X
AD  - Division of Rheumatology, Department of Physical Medicine and Rehabilitation, 
      Necmettin Erbakan University Meram School of Medicine, Konya, Turkey.
FAU - Hizmetli, Sami
AU  - Hizmetli S
AUID- ORCID: 0000-0002-0418-0155
AD  - Division of Rheumatology, Department of Physical Medicine and Rehabilitation, 
      Cumhuriyet University School of Medicine, Sivas, Turkey.
FAU - Kamanli, Ayhan
AU  - Kamanli A
AUID- ORCID: 0000-0001-5299-7250
AD  - Division of Rheumatology and Immunology, Department of Physical Medicine and 
      Rehabilitation, Sakarya University School of Medicine, Sakarya, Turkey.
FAU - Kutluk, Oznur
AU  - Kutluk O
AUID- ORCID: 0000-0003-1037-7381
AD  - Rheumatology Clinic, Antalya Training and Research Hospital, Antalya, Turkey.
FAU - Sen, Nesrin
AU  - Sen N
AUID- ORCID: 0000-0003-0966-0075
AD  - Rheumatology Clinic, Kartal Dr. Lutfi Kirdar Training and Research Hospital, 
      Istanbul, Turkey.
FAU - Sendur, Omer Faruk
AU  - Sendur OF
AUID- ORCID: 0000-0002-0718-9438
AD  - Department of Physical Medicine and Rehabilitation and Algology, Medicana 
      International Hospital, Izmir, Turkey.
FAU - Tolu, Sena
AU  - Tolu S
AUID- ORCID: 0000-0002-1111-3110
AD  - Department of Physical Medicine and Rehabilitation, Medipol University School of 
      Medicine, Istanbul, Turkey.
FAU - Toprak, Murat
AU  - Toprak M
AUID- ORCID: 0000-0002-6490-4645
AD  - Department of Physical Medicine and Rehabilitation, Yuzuncu Yil University School 
      of Medicine, Van, Turkey.
FAU - Tuncer, Tiraje
AU  - Tuncer T
AUID- ORCID: 0000-0001-8654-0603
AD  - Division of Rheumatology, Department of Physical Medicine and Rehabilitation, 
      Akdeniz University School of Medicine, Antalya, Turkey.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20210828
PL  - Germany
TA  - Rheumatol Int
JT  - Rheumatology international
JID - 8206885
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - *Arthritis, Psoriatic/complications/diagnosis
MH  - C-Reactive Protein/analysis
MH  - Cross-Sectional Studies
MH  - Fatigue
MH  - Humans
MH  - Obesity/complications
MH  - Pain
MH  - *Psoriasis
MH  - Quality of Life/psychology
MH  - Severity of Illness Index
MH  - *Spondylitis, Ankylosing/psychology
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Anxiety
OT  - Depression
OT  - Disease activity
OT  - Obesity
OT  - Psoriatic arthritis
OT  - Quality of life
EDAT- 2021/08/29 06:00
MHDA- 2022/04/19 06:00
CRDT- 2021/08/28 12:08
PHST- 2021/05/02 00:00 [received]
PHST- 2021/08/10 00:00 [accepted]
PHST- 2021/08/29 06:00 [pubmed]
PHST- 2022/04/19 06:00 [medline]
PHST- 2021/08/28 12:08 [entrez]
AID - 10.1007/s00296-021-04971-8 [pii]
AID - 10.1007/s00296-021-04971-8 [doi]
PST - ppublish
SO  - Rheumatol Int. 2022 Apr;42(4):659-668. doi: 10.1007/s00296-021-04971-8. Epub 2021 
      Aug 28.