PMID- 34458078 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220426 IS - 2211-3355 (Print) IS - 2211-3355 (Electronic) IS - 2211-3355 (Linking) VI - 24 DP - 2021 Dec TI - Fiber-rich foods delivered to Low-Income Households: A feasibility study of children with prediabetes and spillover effect on their caregivers. PG - 101511 LID - 10.1016/j.pmedr.2021.101511 [doi] LID - 101511 AB - INTRODUCTION: The incidence of pediatric prediabetes and type 2 diabetes mellitus (T2DM) is increasing, with those from low socioeconomic status (SES) households at increased risk. Dietary fiber (e.g., whole grains) is shown to improve glucose control and there is need for innovative strategies that address barriers to consumption (e.g., limited availability). METHODS: Food Overcoming our Diabetes Risk (FoodRx) was a pre-post study (N = 47) that provided 16 weeks of home-delivered whole grains, vegetables, and beans/legumes to households of low-income children in [blinded for submission] who had obesity and prediabetes. Child liking and intake (24-hour diet recalls) was evaluated. Anthropometrics and T2DM-related laboratory measurements (e.g. glycated hemoglobin) were measured for children, and for caregivers to evaluate potential spillover effect. RESULTS: Post-intervention, children increased liking of whole grains, vegetables, and beans/legumes (P < 0.05 for all). Child whole grain intake increased from 1.7 to 2.5 oz-equivalent servings/day (P < 0.001), and the percent of total grain intake that were whole increased from 30% to 44% (P < 0.001). Children's body mass index, blood pressure, and serum triglyceride levels increased (+14.6 mg/dl, P = 0.04). Caregivers fasting glucose (-7.5 mg/dl; P = 0.03), fasting insulin (-2.5 muIU/ml, P = 0.0009) and homeostatic model assessment for insulin resistance (HOMA-IR) decreased (-0.8, P = 0.01). CONCLUSIONS: Home deliveries of fiber rich foods improved liking and intake among children at risk for T2DM. There was spillover effect on caregivers, who demonstrated improvement in T2DM-related laboratory measurements instead of the children. CI - (c) 2021 The Author(s). FAU - Tester, June M AU - Tester JM AD - UCSF Benioff Children's Hospital Oakland. Oakland, CA, USA. FAU - Leak, Tashara M AU - Leak TM AD - Division of Nutritional Sciences, Cornell University, USA. LA - eng PT - Journal Article DEP - 20210803 PL - United States TA - Prev Med Rep JT - Preventive medicine reports JID - 101643766 PMC - PMC8379487 OTO - NOTNLM OT - CSA, community-supported agriculture OT - Endocrinology OT - HOMA-IR, homeostatic model assessment for insulin resistance OT - HbA1c, Hemoglobin A1c OT - Metabolic disorders OT - Prediabetes OT - Preventive medicine OT - SES, socioeconomic status OT - T2DM, type 2 diabetes mellitus COIS- The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2021/08/31 06:00 MHDA- 2021/08/31 06:01 PMCR- 2021/08/03 CRDT- 2021/08/30 05:59 PHST- 2021/03/01 00:00 [received] PHST- 2021/06/07 00:00 [revised] PHST- 2021/07/28 00:00 [accepted] PHST- 2021/08/30 05:59 [entrez] PHST- 2021/08/31 06:00 [pubmed] PHST- 2021/08/31 06:01 [medline] PHST- 2021/08/03 00:00 [pmc-release] AID - S2211-3355(21)00201-1 [pii] AID - 101511 [pii] AID - 10.1016/j.pmedr.2021.101511 [doi] PST - epublish SO - Prev Med Rep. 2021 Aug 3;24:101511. doi: 10.1016/j.pmedr.2021.101511. eCollection 2021 Dec.