PMID- 34461998 OWN - NLM STAT- MEDLINE DCOM- 20220126 LR - 20220126 IS - 2047-2994 (Electronic) IS - 2047-2994 (Linking) VI - 10 IP - 1 DP - 2021 Aug 30 TI - Non-prescriptionxx antibiotic use for people aged 15 years or older for cough in China: a community-based survey. PG - 129 LID - 10.1186/s13756-021-00998-5 [doi] LID - 129 AB - BACKGROUND: Non-prescription antibiotic use at community is a main driver of antimicrobial resistance. Cough is a common condition and prevalent in all townships, including China. This study aims to investigate the non-prescription antibiotic use for cough in China and explore to which extent antibiotic use knowledge was correctly instructed in communities. METHODS: A probability-proportionate-to-size sampling method was adopted to survey from all 14 townships in Yiwu city, China. All participants were investigated by face-to-face interview on Portable Android Devices. The continuous variables were presented by mean and standard deviation or medium and inter-quartile range (IQR). The categorical variables were presented using percentage or constituent ratio. Chi-square test for univariate analysis and logistic regression for multivariate analysis were conducted to assess the odds ratios and 95% confidence intervals, respectively. RESULTS: A total of 3034 respondents across all the 14 townships and the 50 natural villages/streets completed all key items of the questionnaire. Of 2400 (79.10%) respondents stated that they experienced cough in the past 12 months with the medium age of 36.5 (IQR: 26-49) and 12.21% (293/2400) respondents had the non-prescription antibiotic use behavior. Among those 293 respondents, the proportion of non-prescription antibiotic use for cough peaked at around 16% among people aged 30-39 years old. The major sources of antibiotics were pharmacy (77.70%) and/or family storage (43.92%). CONCLUSIONS: Non-prescription antibiotics use for cough is prevalent in the community, especially among people in their thirties. Strengthened drug purchase regulation and well-trained professional pharmacists would be promising alternatives to ameliorate AMR. Moreover, penetrating antibiotics knowledge to common citizens and is an urgent task to alleviate antimicrobial resistance. Therefore, proactive policies and regulations should be made to improve current situations. CI - (c) 2021. The Author(s). FAU - Luo, Yan AU - Luo Y AD - Institute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China. AD - Chinese People's Liberation Army General Hospital, Beijing, China. FAU - Tang, Xuewen AU - Tang X AD - Institute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China. FAU - Ding, Linling AU - Ding L AD - Institute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China. FAU - Shao, Zhujun AU - Shao Z AD - State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. FAU - Yu, Jianxing AU - Yu J AD - State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. FAU - Chen, Yangqing AU - Chen Y AD - School of Public Health, Xiamen University, Xiamen, China. FAU - Zhou, Yang AU - Zhou Y AD - Institute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China. FAU - He, Hanqing AU - He H AUID- ORCID: 0000-0003-0863-5177 AD - Institute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China. hanqinghe@cdc.zj.cn. FAU - Chen, Zhiping AU - Chen Z AD - Institute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China. zhpchen@cdc.zj.cn. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20210830 PL - England TA - Antimicrob Resist Infect Control JT - Antimicrobial resistance and infection control JID - 101585411 RN - 0 (Anti-Bacterial Agents) RN - 0 (Nonprescription Drugs) SB - IM MH - Adolescent MH - Adult MH - Aged MH - Anti-Bacterial Agents/*therapeutic use MH - China MH - Cough/*drug therapy MH - *Drug Misuse/statistics & numerical data MH - Female MH - Humans MH - Logistic Models MH - Male MH - Middle Aged MH - Nonprescription Drugs MH - Odds Ratio MH - Prescriptions MH - Surveys and Questionnaires MH - Young Adult PMC - PMC8404186 OTO - NOTNLM OT - Antibiotic use OT - Community-based OT - Cough OT - Non-prescription COIS- All authors declare that they have no conflicts of interest. EDAT- 2021/09/01 06:00 MHDA- 2022/01/27 06:00 PMCR- 2021/08/30 CRDT- 2021/08/31 05:43 PHST- 2021/05/21 00:00 [received] PHST- 2021/08/21 00:00 [accepted] PHST- 2021/08/31 05:43 [entrez] PHST- 2021/09/01 06:00 [pubmed] PHST- 2022/01/27 06:00 [medline] PHST- 2021/08/30 00:00 [pmc-release] AID - 10.1186/s13756-021-00998-5 [pii] AID - 998 [pii] AID - 10.1186/s13756-021-00998-5 [doi] PST - epublish SO - Antimicrob Resist Infect Control. 2021 Aug 30;10(1):129. doi: 10.1186/s13756-021-00998-5.