PMID- 34466328 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210903 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 13 IP - 7 DP - 2021 Jul TI - Spontaneous Bile Leak in a Patient Without Recent Abdominal Surgery or Trauma. PG - e16702 LID - 10.7759/cureus.16702 [doi] LID - e16702 AB - Bile leaks are a rare occurrence most often seen as a complication of cholecystectomy. Other less common etiologies include endoscopic retrograde cholangiopancreatography (ERCP), percutaneous transhepatic cholangiography (PTC), liver surgery, percutaneous drainage of liver abscesses, living donor hepatectomy, and non-iatrogenic abdominal trauma. In this case study, we present a 67-year-old female with morbid obesity who presented with abdominal pain and was diagnosed with a spontaneous bile leak. She had no history of recent surgery or abdominal trauma. CT revealed that the patient's gallbladder was located in the right lower quadrant, most likely due to mass effect from a large ventral hernia, and possible fluid collection extending from the gallbladder along the surface of the anterior inferior right hepatic lobe. Hepatobiliary iminodiacetic acid (HIDA) was performed due to a concern for cholecystitis. HIDA demonstrated a bile leak in the right upper abdomen of unknown etiology. Initially, there was a concern for gallbladder obstruction. Gastroenterology recommended magnetic resonance cholangiopancreatography (MRCP), however, MRCP was not possible due to the patient's body habitus. The patient had normal liver function tests, was tolerating oral intake, and her abdominal pain resolved, therefore, we became less suspicious of gallbladder obstruction. This case suggests that bile leak should be included in the differential diagnosis for abdominal pain even in patients who have not had recent abdominal surgery or procedures. This case also highlights the unique anatomical finding of a right lower quadrant gallbladder secondary to mass effect from a large ventral hernia. CI - Copyright (c) 2021, Micheli et al. FAU - Micheli, Daniel AU - Micheli D AD - Family and Community Medicine, Western Michigan University Homer Stryker School of Medicine, Kalamazoo, USA. FAU - Patel, Keshav R AU - Patel KR AD - Internal Medicine, Western Michigan University Homer Stryker School of Medicine, Kalamazoo, USA. FAU - Li, Tong AU - Li T AD - Family and Community Medicine, Western Michigan University Homer Stryker School of Medicine, Kalamazoo, USA. FAU - Kassir, Mahmoud AU - Kassir M AD - Family and Community Medicine, Western Michigan University Homer Stryker School of Medicine, Kalamazoo, USA. FAU - Eichorn, Wesley AU - Eichorn W AD - Family and Community Medicine, Western Michigan University Homer Stryker School of Medicine, Kalamazoo, USA. LA - eng PT - Case Reports DEP - 20210728 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC8397512 OTO - NOTNLM OT - abdominal pain OT - bile duct injury OT - biliary tree OT - spontaneous bile leak OT - ventral hernia COIS- The authors have declared that no competing interests exist. EDAT- 2021/09/02 06:00 MHDA- 2021/09/02 06:01 PMCR- 2021/07/28 CRDT- 2021/09/01 07:24 PHST- 2021/07/28 00:00 [accepted] PHST- 2021/09/01 07:24 [entrez] PHST- 2021/09/02 06:00 [pubmed] PHST- 2021/09/02 06:01 [medline] PHST- 2021/07/28 00:00 [pmc-release] AID - 10.7759/cureus.16702 [doi] PST - epublish SO - Cureus. 2021 Jul 28;13(7):e16702. doi: 10.7759/cureus.16702. eCollection 2021 Jul.