PMID- 34468401
OWN - NLM
STAT- MEDLINE
DCOM- 20211015
LR  - 20230916
IS  - 1752-2978 (Electronic)
IS  - 1752-296X (Print)
IS  - 1752-296X (Linking)
VI  - 28
IP  - 5
DP  - 2021 Oct 1
TI  - Effect of low carbohydrate diets on insulin resistance and the metabolic 
      syndrome.
PG  - 463-468
LID - 10.1097/MED.0000000000000659 [doi]
AB  - PURPOSE OF REVIEW: This review outlines recent research in the application of low 
      carbohydrate diets (LCD) for insulin resistance (IR) and metabolic syndrome 
      (MetS). RECENT FINDINGS: Studies included in this review explore how a LCD can be 
      used in the management of patients with IR and MetS. LCDs have been shown to 
      result in Type 2 Diabetes Mellitus (T2DM) remission, improve lipid profiles and 
      dramatically reduce intrahepatic fat. SUMMARY: The field of nutritional science 
      is notoriously complex. The LCD has a simple narrative, which can easily and 
      safely be applied in clinical practice. Current guidelines recognise and 
      encourage the use of LCD as a valid option for patients with T2DM and obesity. 
      Structured, evidence-based education should be available for all clinicians to 
      increase confidence and ensure consistency and quality control. Further 
      real-world evidence into the application and scalability of a LCD are required. 
      The use of digital health solutions and improved health technology should see 
      significant advances in this field, with dietary habit being driven by 
      patient-derived health data in response to food, and not population-based food 
      guidelines. The narrative around MetS and IR needs to change from progression to 
      remission, with a LCD being a valid option for this.
CI  - Copyright (c) 2021 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Foley, Peter J
AU  - Foley PJ
AD  - Hanham Health, Bristol, UK.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Curr Opin Endocrinol Diabetes Obes
JT  - Current opinion in endocrinology, diabetes, and obesity
JID - 101308636
SB  - IM
MH  - *Diabetes Mellitus, Type 2
MH  - Diet, Carbohydrate-Restricted
MH  - Humans
MH  - *Insulin Resistance
MH  - *Metabolic Syndrome
MH  - Obesity
PMC - PMC8500369
COIS- P.F. is the Clinical Safety Officer and a Medical Advisor for Diabetes Digital 
      Media, for which he receives financial compensation. He declares no other 
      conflicts of interest.
EDAT- 2021/09/02 06:00
MHDA- 2021/10/16 06:00
PMCR- 2021/10/08
CRDT- 2021/09/01 12:26
PHST- 2021/09/01 12:26 [entrez]
PHST- 2021/09/02 06:00 [pubmed]
PHST- 2021/10/16 06:00 [medline]
PHST- 2021/10/08 00:00 [pmc-release]
AID - 01266029-202110000-00007 [pii]
AID - MED280507 [pii]
AID - 10.1097/MED.0000000000000659 [doi]
PST - ppublish
SO  - Curr Opin Endocrinol Diabetes Obes. 2021 Oct 1;28(5):463-468. doi: 
      10.1097/MED.0000000000000659.