PMID- 34472358
OWN - NLM
STAT- MEDLINE
DCOM- 20211011
LR  - 20211011
IS  - 1552-695X (Electronic)
IS  - 1534-7354 (Print)
IS  - 1534-7354 (Linking)
VI  - 20
DP  - 2021 Jan-Dec
TI  - Relationship Between Physical Function and Health Utility in Patients Undergoing 
      Surgical Treatment for Malignant Pleural Mesothelioma.
PG  - 15347354211043508
LID - 10.1177/15347354211043508 [doi]
LID - 15347354211043508
AB  - PURPOSE: Health utility, which is a measure of patient-reported outcome (PRO), 
      has recently been used in health-related quality of life for patients with 
      various cancers. However, the relationship between health utility and the 
      physical function and of patients undergoing pleurectomy/decortication (P/D) as 
      surgical treatment for malignant pleural mesothelioma (MPM) has not been reported 
      in the perioperative and convalescent phases. This study aimed to evaluate the 
      perioperative and postoperative health utility of patients undergoing P/D for MPM 
      at one year postoperatively and to examine the relationship with physical 
      function. METHODS: We included patients underwent P/D. Grip strength, knee 
      extension strength, 6-minute walk distance (6MWD), forced vital capacity (FVC), 
      and forced expiratory volume in one second (FEV1) were measured to assess 
      physical function, and the Short-Form Six-Dimension (SF-6D) was completed to 
      assess health utility. These assessments were performed preoperatively, 
      postoperatively, and one year postoperatively. Statistical analysis was performed 
      using one-way analysis of variance for comparison of pre and postoperative and 
      one year mean values. RESULTS: There were 24 subjects (23 males, 65.5+/-8.3 year). 
      SF-6D, 6MWD, FVC, and FEV1 values one year operatively improved significantly 
      compared with postoperative. Additionally, SF-6D was correlated with 6MWD. 
      CONCLUSION: Health utility were also correlated with exercise capacity.
FAU - Tanaka, Takashi
AU  - Tanaka T
AUID- ORCID: 0000-0001-9521-4973
AD  - Hyogo College of Medicine Hospital, Nishinomiya, Hyogo, Japan.
FAU - Morishita, Shinichiro
AU  - Morishita S
AD  - Fukushima Medical University, Sakaemachi, Fukushima, Japan.
AD  - Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
FAU - Hashimoto, Masaki
AU  - Hashimoto M
AD  - Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
FAU - Nakamichi, Toru
AU  - Nakamichi T
AD  - Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
FAU - Uchiyama, Yuki
AU  - Uchiyama Y
AD  - Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
FAU - Hasegawa, Seiki
AU  - Hasegawa S
AD  - Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
FAU - Domen, Kazuhisa
AU  - Domen K
AD  - Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Integr Cancer Ther
JT  - Integrative cancer therapies
JID - 101128834
SB  - IM
MH  - Humans
MH  - *Lung Neoplasms/surgery
MH  - Male
MH  - *Mesothelioma/surgery
MH  - *Mesothelioma, Malignant
MH  - *Pleural Neoplasms/surgery
MH  - Pneumonectomy
MH  - Quality of Life
MH  - Treatment Outcome
PMC - PMC8419542
OTO - NOTNLM
OT  - convalescent phase
OT  - health utility
OT  - malignant pleural mesothelioma
OT  - patient-reported outcome
OT  - physical function
OT  - pleurectomy/decortication
OT  - quality of life
OT  - rehabilitation
COIS- Declaration of Conflicting Interests: The author(s) declared no potential 
      conflicts of interest with respect to the research, authorship, and/or 
      publication of this article.
EDAT- 2021/09/03 06:00
MHDA- 2021/10/12 06:00
PMCR- 2021/09/02
CRDT- 2021/09/02 08:41
PHST- 2021/09/02 08:41 [entrez]
PHST- 2021/09/03 06:00 [pubmed]
PHST- 2021/10/12 06:00 [medline]
PHST- 2021/09/02 00:00 [pmc-release]
AID - 10.1177_15347354211043508 [pii]
AID - 10.1177/15347354211043508 [doi]
PST - ppublish
SO  - Integr Cancer Ther. 2021 Jan-Dec;20:15347354211043508. doi: 
      10.1177/15347354211043508.