PMID- 34472754 OWN - NLM STAT- MEDLINE DCOM- 20210903 LR - 20210903 IS - 1000-0607 (Print) IS - 1000-0607 (Linking) VI - 46 IP - 8 DP - 2021 Aug 25 TI - [Effect of transcutaneous electric acupoints stimulation on vascular endothelial function and inflammatory factors after percutaneous coronary intervention]. PG - 684-9 LID - 10.13702/j.1000-0607.200784 [doi] AB - OBJECTIVE: To observe the effect of transcutaneous electric acupoints stimulation (TEAS) on vascular endothelial function and inflammatory factors after percutaneous coronary intervention (PCI) in patients. METHODS: A total of 94 patients with coronary heart disease and undergoing PCI were randomized into a TEAS group and a sham-TEAS group, 47 cases in each one. In the TEAS group, TEAS started at unilateral Neiguan (PC6) and Ximen (PC4) 30 min before PCI till the end of PCI. In the sham-TEAS group, the procedure and persistent time were same as the TEAS group, but no electric stimulation was performed. Before treatment and at 8 h and 24 h after PCI, the levels of serum endothelin-1 (ET-1), von Willebrand factor (vWF), nitric oxide (NO), blood flow dependent diastolic function (FMD), interleukin-6 (IL-6), inteleukin-10 (IL-10), matrix metalloproteinase-9 (MMP-9) and high-sensitivity C-reactive protein (hs-CRP) were detected in the patients successively. RESULTS: Compared with the levels before PCI, the levels of ET-1 and vWF were all increased at 8 h and 24 h after PCI in the two groups (P<0.05) and the levels in the TEAS group were remarkably lower than those in the sham-TEAS group (P<0.05). Compared with the levels before PCI, the levels of NO and FMD at 8 h and 24 h after PCI were all reduced in the two groups (P<0.05) and the levels in the TEAS group were higher obviously than those in the sham-TEAS group (P<0.05). Compared with the levels before PCI, the levels of hs-CRP, MMP-9, IL-6 and IL-10 were all increased at 8 h and 24 h after PCI in the two groups (P<0.05); Compared with the sham-TEAS group, the levels of hs-CRP, MMP-9 and IL-6 were reduced and the level of IL-10 was increased at 8 h and 24 h after PCI in the TEAS group (P<0.05). CONCLUSION: TEAS effectively improves the vascular endothelial function and reduces serum inflammatory factors after PCI. FAU - Zhao, Fang-Chao AU - Zhao FC AD - Cardiothoracic Surgery Department of Tangshan Municipal People's Hospital Affiliated to North China University of Science and Technology, Tangshan 063000, Hebei Province, China. FAU - Gao, Yan-Lin AU - Gao YL AD - Graduate School of Hebei Medical University, Shijiazhuang 050000. FAU - Cai, Hua-Shan AU - Cai HS AD - Graduate School of Hebei Medical University, Shijiazhuang 050000. FAU - Song, Shi-Wei AU - Song SW AD - Cardiothoracic Surgery Department of Tangshan Municipal People's Hospital Affiliated to North China University of Science and Technology, Tangshan 063000, Hebei Province, China. FAU - Liu, Xiao-Hui AU - Liu XH AD - Cardiothoracic Surgery Department of Tangshan Municipal People's Hospital Affiliated to North China University of Science and Technology, Tangshan 063000, Hebei Province, China. FAU - Liu, Jian-Ming AU - Liu JM AD - Cardiothoracic Surgery Department of Tangshan Municipal People's Hospital Affiliated to North China University of Science and Technology, Tangshan 063000, Hebei Province, China. LA - chi PT - Journal Article PT - Randomized Controlled Trial PL - China TA - Zhen Ci Yan Jiu JT - Zhen ci yan jiu = Acupuncture research JID - 8507710 RN - 9007-41-4 (C-Reactive Protein) SB - IM MH - Acupuncture Points MH - C-Reactive Protein MH - *Coronary Disease/therapy MH - Humans MH - *Percutaneous Coronary Intervention/adverse effects MH - *Transcutaneous Electric Nerve Stimulation OTO - NOTNLM OT - Coronary heart disease OT - Inflammatory factors OT - Percutaneous coronary intervention OT - Transcutaneous acupoint electrical stimulation OT - Vascular endothelial function EDAT- 2021/09/03 06:00 MHDA- 2021/09/04 06:00 CRDT- 2021/09/02 09:02 PHST- 2021/09/02 09:02 [entrez] PHST- 2021/09/03 06:00 [pubmed] PHST- 2021/09/04 06:00 [medline] AID - 10.13702/j.1000-0607.200784 [doi] PST - ppublish SO - Zhen Ci Yan Jiu. 2021 Aug 25;46(8):684-9. doi: 10.13702/j.1000-0607.200784.