PMID- 34480185 OWN - NLM STAT- MEDLINE DCOM- 20220126 LR - 20220531 IS - 2472-5625 (Electronic) IS - 2472-5625 (Linking) VI - 6 IP - 1 DP - 2022 Jan 7 TI - Hypertrophic pachymeningitis in eosinophilic granulomatosis with polyangiitis. PG - 80-82 LID - 10.1093/mrcr/rxab009 [doi] AB - Eosinophilic granulomatosis with polyangiitis (EGPA) is one of the anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV), which is characterised by systemic small vessels vasculitis with associated eosinophilia. Hypertrophic pachymeningitis (HP) is an inflammatory disease in which the cerebral or spinal dura mater is thickened. AAV other than EGPA may sometimes develop HP; however, patients with EGPA rarely develop HP. This is the case of myeloperoxidase-ANCA-positive EGPA that presented with headache and blurred vision and was diagnosed with HP. It was successfully treated with pulsed steroid therapy and intravenous cyclophosphamide without any relapse for more than 4 years. CI - (c) Japan College of Rheumatology 2021. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. FAU - Izuka, Shinji AU - Izuka S AUID- ORCID: 0000-0002-9724-4911 AD - Division of Rheumatic Diseases, National Center for Global Health and Medicine, Tokyo, Japan. FAU - Yamashita, Hiroyuki AU - Yamashita H AUID- ORCID: 0000-0002-0022-1941 AD - Division of Rheumatic Diseases, National Center for Global Health and Medicine, Tokyo, Japan. FAU - Takahashi, Yuko AU - Takahashi Y AD - Division of Rheumatic Diseases, National Center for Global Health and Medicine, Tokyo, Japan. FAU - Kaneko, Hiroshi AU - Kaneko H AD - Division of Rheumatic Diseases, National Center for Global Health and Medicine, Tokyo, Japan. LA - eng PT - Case Reports PT - Journal Article PL - England TA - Mod Rheumatol Case Rep JT - Modern rheumatology case reports JID - 101761026 RN - 0 (Antibodies, Antineutrophil Cytoplasmic) SB - IM MH - *Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis MH - Antibodies, Antineutrophil Cytoplasmic MH - *Churg-Strauss Syndrome/complications/diagnosis/drug therapy MH - *Granulomatosis with Polyangiitis/complications/diagnosis/drug therapy MH - Humans MH - *Meningitis/diagnosis/drug therapy/etiology OTO - NOTNLM OT - ANCA-associated vasculitis OT - Hypertrophic pachymeningitis OT - eosinophilic granulomatosis with polyangiitis OT - myeloperoxidase-ANCA OT - vasculitis EDAT- 2021/09/05 06:00 MHDA- 2022/01/27 06:00 CRDT- 2021/09/04 06:09 PHST- 2021/04/08 00:00 [received] PHST- 2021/05/29 00:00 [revised] PHST- 2021/06/11 00:00 [accepted] PHST- 2021/09/05 06:00 [pubmed] PHST- 2022/01/27 06:00 [medline] PHST- 2021/09/04 06:09 [entrez] AID - 6363920 [pii] AID - 10.1093/mrcr/rxab009 [doi] PST - ppublish SO - Mod Rheumatol Case Rep. 2022 Jan 7;6(1):80-82. doi: 10.1093/mrcr/rxab009.