PMID- 34493435
OWN - NLM
STAT- MEDLINE
DCOM- 20220107
LR  - 20220107
IS  - 1532-8422 (Electronic)
IS  - 1053-0770 (Linking)
VI  - 35
IP  - 12
DP  - 2021 Dec
TI  - Preoperative and ICU Scoring Models for Predicting the In-Hospital Mortality of 
      Patients With Ruptured Abdominal Aortic Aneurysms.
PG  - 3700-3707
LID - S1053-0770(21)00687-X [pii]
LID - 10.1053/j.jvca.2021.08.015 [doi]
AB  - OBJECTIVES: This study's objective was to compare several preoperative and 
      intensive care unit (ICU) prognostic scoring systems for predicting the 
      in-hospital mortality of ruptured abdominal aortic aneurysms (RAAAs). DESIGN: 
      Retrospective cohort study. SETTING: Single tertiary university center. 
      PARTICIPANTS: The study comprised 157 patients. INTERVENTIONS: None. MEASUREMENTS 
      AND MAIN RESULTS: A total of 157 patients (82% male) presented with RAAA at 
      Charite University Hospital from January 2011 to December 2020. The mean age was 
      74 years (standard deviation ten years). In-hospital mortality was 29% (n = 45), 
      of whom nine patients (6%) died en route to the operating room, 13 (8%) on the 
      operating table, and 23 (15%) in the ICU. A total of 135 patients (86%) were 
      admitted to the ICU. All six models demonstrated good discriminating performance 
      between survivors and nonsurvivors. Overall, the area under the curve (AUC) for 
      RAAA preoperative scores was greater than those for ICU scores. The largest AUC 
      was achieved with the Vascular Study Group of New England (VSGNE) RAAA risk score 
      (AUC = 0.87 for all patients, AUC = 0.84 for patients admitted to the ICU), 
      followed by Hardman Index (AUC = 0.83 for all patients, AUC = 0.81 for patients 
      admitted to the ICU), and Glasgow Aneurysm Score (AUC = 0.74 for all patients, 
      AUC = 0.83 for patients admitted to the ICU). The largest AUC for ICU scores 
      (only patients admitted to the ICU) was achieved with Simplified Acute Physiology 
      Score II (0.75), followed by Sepsis-related Organ Failure Assessment (0.73), and 
      Acute Physiology and Chronic Health Evaluation II (0.71). CONCLUSIONS: 
      Preoperative and ICU scores can predict the mortality of patients presenting with 
      RAAA. In addition, the discriminatory ability of preoperative scores between 
      survivors and nonsurvivors was larger than that for ICU scores.
CI  - Copyright (c) 2021 Elsevier Inc. All rights reserved.
FAU - Omran, Safwan
AU  - Omran S
AD  - Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat 
      Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, 
      Department of Vascular Surgery, Berlin, Germany. Electronic address: 
      safwan.omran@charite.de.
FAU - Groger, Steffen
AU  - Groger S
AD  - Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat 
      Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, 
      Department of Vascular Surgery, Berlin, Germany.
FAU - Schawe, Larissa
AU  - Schawe L
AD  - Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat 
      Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, 
      Department of Vascular Surgery, Berlin, Germany.
FAU - Berger, Christian
AU  - Berger C
AD  - Charite - Universitatsmedizin Berlin, Corporate Member of Freie Universitat and 
      Humboldt Universitat zu Berlin, Department of Anesthesiology and Intensive Care 
      Medicine, Charite Campus Benjamin Franklin, Berlin, Germany.
FAU - Konietschke, Frank
AU  - Konietschke F
AD  - Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat 
      Berlin, Humboldt-Universitat zu Berlin, Institute of Medical Biometrics and 
      Clinical Epidemiology and Berlin Institute of Health (BIH), Berlin, Germany.
FAU - Treskatsch, Sascha
AU  - Treskatsch S
AD  - Charite - Universitatsmedizin Berlin, Corporate Member of Freie Universitat and 
      Humboldt Universitat zu Berlin, Department of Anesthesiology and Intensive Care 
      Medicine, Charite Campus Benjamin Franklin, Berlin, Germany.
FAU - Greiner, Andreas
AU  - Greiner A
AD  - Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat 
      Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, 
      Department of Vascular Surgery, Berlin, Germany.
FAU - Angermair, Stefan
AU  - Angermair S
AD  - Charite - Universitatsmedizin Berlin, Corporate Member of Freie Universitat and 
      Humboldt Universitat zu Berlin, Department of Anesthesiology and Intensive Care 
      Medicine, Charite Campus Benjamin Franklin, Berlin, Germany.
LA  - eng
PT  - Journal Article
DEP - 20210814
PL  - United States
TA  - J Cardiothorac Vasc Anesth
JT  - Journal of cardiothoracic and vascular anesthesia
JID - 9110208
SB  - IM
CIN - J Cardiothorac Vasc Anesth. 2021 Dec;35(12):3708-3710. PMID: 34627710
MH  - Aged
MH  - *Aortic Aneurysm, Abdominal/surgery
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Intensive Care Units
MH  - Male
MH  - Prognosis
MH  - ROC Curve
MH  - Retrospective Studies
OTO - NOTNLM
OT  - APACHE II
OT  - SAPS II
OT  - SOFA
OT  - VSGNE
OT  - abdominal aortic aneurysm
OT  - aortic rupture
EDAT- 2021/09/09 06:00
MHDA- 2022/01/08 06:00
CRDT- 2021/09/08 05:50
PHST- 2021/05/25 00:00 [received]
PHST- 2021/08/06 00:00 [revised]
PHST- 2021/08/09 00:00 [accepted]
PHST- 2021/09/09 06:00 [pubmed]
PHST- 2022/01/08 06:00 [medline]
PHST- 2021/09/08 05:50 [entrez]
AID - S1053-0770(21)00687-X [pii]
AID - 10.1053/j.jvca.2021.08.015 [doi]
PST - ppublish
SO  - J Cardiothorac Vasc Anesth. 2021 Dec;35(12):3700-3707. doi: 
      10.1053/j.jvca.2021.08.015. Epub 2021 Aug 14.