PMID- 34498593
OWN - NLM
STAT- MEDLINE
DCOM- 20211015
LR  - 20240403
IS  - 2149-2271 (Electronic)
IS  - 2149-2263 (Print)
IS  - 2149-2263 (Linking)
VI  - 25
IP  - 9
DP  - 2021 Sep
TI  - Post percutaneous coronary intervention hemoglobin levels predict in-hospital 
      mortality in patients with STEMI treated with primary percutaneous coronary 
      intervention.
PG  - 623-629
LID - 10.5152/AnatolJCardiol.2021.07282 [doi]
AB  - OBJECTIVE: In this study, we aimed to determine whether admission hemoglobin 
      versus post-percutaneous coronary intervention (PCI) hemoglobin level at 24 hours 
      is a predictor of in-hospital mortality for patients with ST elevation myocardial 
      infarction (STEMI) without evidence of clinical hemorrhage who underwent primary 
      PCI. METHODS: In this study, we included 1,444 consecutive patients with STEMI 
      who underwent primary PCI at a tertiary heart hospital. The primary outcome of 
      the study was the in-hospital all-cause mortality. We used the penalized maximum 
      likelihood estimation (PMLE) logistic regression method to examine the 
      relationship between primary outcome and candidate predictors. RESULTS: In total, 
      172 (11.9%) patients died during the in-hospital course. According to a PMLE 
      logistic regression analysis, age, KILLIP class >/=2, pre-PCI thrombolysis in 
      myocardial infarction (TIMI) flow <3, systolic blood pressure, creatinine, 
      glycoprotein IIb/IIIa inhibitor use, and post-PCI hemoglobin levels at 24 hours 
      were predictors of in-hospital mortality. The relative importance of post-PCI 
      hemoglobin at 24 hours (contributing 6% of the explainable outcome in the model) 
      was significantly higher than admission hemoglobin (contributing only 0.1% of the 
      explainable outcome in the model). CONCLUSION: This study demonstrated that 
      post-PCI hemoglobin levels were independently associated with in-hospital 
      survival in patients with STEMI without evidence of bleeding following primary 
      PCI. In addition, post-PCI hemoglobin was a better predictor of in-hospital 
      mortality than admission hemoglobin for patients with STEMI who underwent primary 
      PCI.
FAU - Zeren, Gonul
AU  - Zeren G
AD  - Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital; Istanbul-Turkey.
FAU - Avci, Ilhan Ilker
AU  - Avci II
AD  - Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital; Istanbul-Turkey.
FAU - Simsek, Baris
AU  - Simsek B
AD  - Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital; Istanbul-Turkey.
FAU - Sungur, Azmi
AU  - Sungur A
AD  - Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital; Istanbul-Turkey.
FAU - Cinar, Tufan
AU  - Cinar T
AD  - Department of Cardiology, Sultan Abdulhamid Han Training and Research Hospital; 
      Istanbul-Turkey.
FAU - Tanik, Veysel Ozan
AU  - Tanik VO
AD  - Department of Cardiology, Ankara Diskapi Yildirim Beyazit Training and Research 
      Hospital; Istanbul-Turkey.
FAU - Genc, Duygu
AU  - Genc D
AD  - Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital; Istanbul-Turkey.
FAU - Cinier, Goksel
AU  - Cinier G
AD  - Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital; Istanbul-Turkey.
FAU - Karabay, Can Yucel
AU  - Karabay CY
AD  - Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital; Istanbul-Turkey.
LA  - eng
PT  - Journal Article
PL  - Turkey
TA  - Anatol J Cardiol
JT  - Anatolian journal of cardiology
JID - 101652981
SB  - IM
MH  - Hospital Mortality
MH  - Humans
MH  - *Myocardial Infarction/therapy
MH  - *Percutaneous Coronary Intervention
MH  - *ST Elevation Myocardial Infarction/surgery
MH  - Treatment Outcome
PMC - PMC8443206
COIS- Conflict of interest: None declared.
EDAT- 2021/09/10 06:00
MHDA- 2021/10/16 06:00
PMCR- 2021/08/17
CRDT- 2021/09/09 08:42
PHST- 2021/09/09 08:42 [entrez]
PHST- 2021/09/10 06:00 [pubmed]
PHST- 2021/10/16 06:00 [medline]
PHST- 2021/08/17 00:00 [pmc-release]
AID - ajc-25-9-623 [pii]
AID - 10.5152/AnatolJCardiol.2021.07282 [doi]
PST - ppublish
SO  - Anatol J Cardiol. 2021 Sep;25(9):623-629. doi: 10.5152/AnatolJCardiol.2021.07282.